BR112013004858A8 - derivados de 4-{[(piridin-3-il-metil) aminocarbonil]amino}benzeno-sulfona como inibidores de nampt para terapia de doenças tal como câncer - Google Patents
derivados de 4-{[(piridin-3-il-metil) aminocarbonil]amino}benzeno-sulfona como inibidores de nampt para terapia de doenças tal como câncerInfo
- Publication number
- BR112013004858A8 BR112013004858A8 BR112013004858A BR112013004858A BR112013004858A8 BR 112013004858 A8 BR112013004858 A8 BR 112013004858A8 BR 112013004858 A BR112013004858 A BR 112013004858A BR 112013004858 A BR112013004858 A BR 112013004858A BR 112013004858 A8 BR112013004858 A8 BR 112013004858A8
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- BR
- Brazil
- Prior art keywords
- aminocarbonyl
- pyridin
- cancer
- therapy
- diseases
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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US38604410P | 2010-09-24 | 2010-09-24 | |
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PCT/US2011/050320 WO2012031196A1 (en) | 2010-09-03 | 2011-09-02 | 4- { [ ( pyridin- 3 - yl -methyl) aminocarbonyl] amino} benzene - sulfone derivatives as nampt inhibitors for therapy of diseases such as cancer |
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CN (2) | CN103270023B (pt) |
AR (1) | AR082887A1 (pt) |
AU (1) | AU2011295724B2 (pt) |
BR (1) | BR112013004858A8 (pt) |
CA (1) | CA2809391A1 (pt) |
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RU (2) | RU2617424C2 (pt) |
TW (1) | TW201217359A (pt) |
WO (1) | WO2012031196A1 (pt) |
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PT2820008T (pt) | 2012-03-02 | 2017-05-05 | Genentech Inc | Amidas amido-espirocíclicas e derivados de sulfonamidas |
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US9296723B2 (en) | 2012-05-11 | 2016-03-29 | Abbvie Inc. | NAMPT inhibitors |
BR112014028042A2 (pt) * | 2012-05-11 | 2017-06-27 | Abbvie Inc | inibidores de nampt |
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2011
- 2011-09-02 CA CA2809391A patent/CA2809391A1/en not_active Abandoned
- 2011-09-02 CN CN201180053248.9A patent/CN103270023B/zh not_active Expired - Fee Related
- 2011-09-02 TW TW100131860A patent/TW201217359A/zh unknown
- 2011-09-02 KR KR1020137008447A patent/KR20130114653A/ko not_active Application Discontinuation
- 2011-09-02 RU RU2013114844A patent/RU2617424C2/ru active IP Right Revival
- 2011-09-02 MX MX2013002431A patent/MX342481B/es active IP Right Grant
- 2011-09-02 AR ARP110103220A patent/AR082887A1/es unknown
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- 2011-09-02 RU RU2016116533A patent/RU2016116533A/ru unknown
- 2011-09-02 WO PCT/US2011/050320 patent/WO2012031196A1/en active Application Filing
- 2011-09-02 EP EP11758024.1A patent/EP2611777B1/en not_active Not-in-force
- 2011-09-02 BR BR112013004858A patent/BR112013004858A8/pt not_active Application Discontinuation
- 2011-09-02 JP JP2013527339A patent/JP6038792B2/ja not_active Expired - Fee Related
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CN103270023A (zh) | 2013-08-28 |
MX2013002431A (es) | 2013-06-03 |
JP6038792B2 (ja) | 2016-12-07 |
TW201217359A (en) | 2012-05-01 |
AU2011295724A1 (en) | 2013-05-02 |
KR20130114653A (ko) | 2013-10-17 |
RU2016116533A (ru) | 2018-11-30 |
RU2013114844A (ru) | 2014-10-10 |
RU2617424C2 (ru) | 2017-04-25 |
EP2611777B1 (en) | 2016-05-11 |
JP2017019825A (ja) | 2017-01-26 |
US20190270721A1 (en) | 2019-09-05 |
WO2012031196A9 (en) | 2013-06-13 |
JP2013536868A (ja) | 2013-09-26 |
RU2016116533A3 (pt) | 2018-11-30 |
MX342481B (es) | 2016-09-30 |
US11279687B2 (en) | 2022-03-22 |
AU2011295724A8 (en) | 2013-06-20 |
US20180291000A1 (en) | 2018-10-11 |
CA2809391A1 (en) | 2012-03-08 |
BR112013004858A2 (pt) | 2016-06-07 |
US10647695B2 (en) | 2020-05-12 |
CN103270023B (zh) | 2016-11-02 |
CN106986856A (zh) | 2017-07-28 |
AR082887A1 (es) | 2013-01-16 |
WO2012031196A1 (en) | 2012-03-08 |
EP2611777A1 (en) | 2013-07-10 |
AU2011295724B2 (en) | 2016-05-12 |
US10329275B2 (en) | 2019-06-25 |
US20130273034A1 (en) | 2013-10-17 |
US20200283403A1 (en) | 2020-09-10 |
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