RS52743B - (2s,3r)-n-(2-((3-piridinil)metil)-1-azabiciklo[2.2.2]okt-3-il)benzofuran-2-karboksamid, novi oblici soli i postupci za njihovu upotrebu - Google Patents

(2s,3r)-n-(2-((3-piridinil)metil)-1-azabiciklo[2.2.2]okt-3-il)benzofuran-2-karboksamid, novi oblici soli i postupci za njihovu upotrebu

Info

Publication number
RS52743B
RS52743B RS20130115A RSP20130115A RS52743B RS 52743 B RS52743 B RS 52743B RS 20130115 A RS20130115 A RS 20130115A RS P20130115 A RSP20130115 A RS P20130115A RS 52743 B RS52743 B RS 52743B
Authority
RS
Serbia
Prior art keywords
methyl
azabicyclo
oct
pyridinyl
benzofuran
Prior art date
Application number
RS20130115A
Other languages
English (en)
Serbian (sr)
Inventor
Lan Miao
John Genus
Merouane Bencherif
Lisa Benson
Gary Maurice Dull
Nikolai Fedorov
Gregory J. Gatto
Kristen G. Jordan
Jacob Mathew
Anatoly A. Mazurov
Julio A. Munoz
Inigo Pfeiffer
Sondra Pfeiffer
Teresa Y. Phillips
Original Assignee
Targacept Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39945177&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS52743(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Targacept Inc. filed Critical Targacept Inc.
Publication of RS52743B publication Critical patent/RS52743B/sr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20130115A 2007-08-02 2008-08-01 (2s,3r)-n-(2-((3-piridinil)metil)-1-azabiciklo[2.2.2]okt-3-il)benzofuran-2-karboksamid, novi oblici soli i postupci za njihovu upotrebu RS52743B (sr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95361407P 2007-08-02 2007-08-02
US95361007P 2007-08-02 2007-08-02
US95361307P 2007-08-02 2007-08-02
US97165407P 2007-09-12 2007-09-12
PCT/US2008/071872 WO2009018505A1 (en) 2007-08-02 2008-08-01 (2s,3r)-n-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms, and methods of use thereof

Publications (1)

Publication Number Publication Date
RS52743B true RS52743B (sr) 2013-08-30

Family

ID=39945177

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20130115A RS52743B (sr) 2007-08-02 2008-08-01 (2s,3r)-n-(2-((3-piridinil)metil)-1-azabiciklo[2.2.2]okt-3-il)benzofuran-2-karboksamid, novi oblici soli i postupci za njihovu upotrebu

Country Status (35)

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US (6) US7981906B2 (enExample)
EP (6) EP2431037B1 (enExample)
JP (4) JP2010535252A (enExample)
KR (2) KR20100063043A (enExample)
CN (4) CN103172628A (enExample)
AR (1) AR067775A1 (enExample)
AU (3) AU2008283813A1 (enExample)
BR (2) BRPI0815009A2 (enExample)
CA (2) CA2694504C (enExample)
CL (3) CL2008002271A1 (enExample)
CO (2) CO6260080A2 (enExample)
CY (1) CY1113561T1 (enExample)
DK (2) DK2182949T3 (enExample)
EC (2) ECSP10010008A (enExample)
ES (3) ES2606752T3 (enExample)
HR (1) HRP20130286T1 (enExample)
HU (1) HUE030387T2 (enExample)
IL (1) IL218976A0 (enExample)
ME (1) ME01508B (enExample)
MX (3) MX346451B (enExample)
MY (1) MY148002A (enExample)
NO (2) NO20100078L (enExample)
NZ (2) NZ582828A (enExample)
PE (3) PE20121820A1 (enExample)
PH (2) PH12012501514A1 (enExample)
PL (1) PL2182949T3 (enExample)
PT (1) PT2182949E (enExample)
RS (1) RS52743B (enExample)
RU (2) RU2012140148A (enExample)
SA (2) SA08290475B1 (enExample)
SI (1) SI2182949T1 (enExample)
TW (3) TWI429435B (enExample)
UY (1) UY31265A (enExample)
WO (2) WO2009018511A2 (enExample)
ZA (1) ZA201000719B (enExample)

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