AU7083596A - Novel substituted azacyclic or azabicyclic compounds - Google Patents

Novel substituted azacyclic or azabicyclic compounds

Info

Publication number
AU7083596A
AU7083596A AU70835/96A AU7083596A AU7083596A AU 7083596 A AU7083596 A AU 7083596A AU 70835/96 A AU70835/96 A AU 70835/96A AU 7083596 A AU7083596 A AU 7083596A AU 7083596 A AU7083596 A AU 7083596A
Authority
AU
Australia
Prior art keywords
novel substituted
azabicyclic compounds
substituted azacyclic
azacyclic
azabicyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU70835/96A
Inventor
Holger C. Hansen
John Bondo Hansen
Preben Houlberg Olesen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU7083596A publication Critical patent/AU7083596A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
AU70835/96A 1995-09-22 1996-09-20 Novel substituted azacyclic or azabicyclic compounds Abandoned AU7083596A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK106395 1995-09-22
DK1063/95 1995-09-22
DK116695 1995-10-16
DK1166/95 1995-10-16
PCT/DK1996/000401 WO1997011072A1 (en) 1995-09-22 1996-09-20 Novel substituted azacyclic or azabicyclic compounds

Publications (1)

Publication Number Publication Date
AU7083596A true AU7083596A (en) 1997-04-09

Family

ID=26065156

Family Applications (1)

Application Number Title Priority Date Filing Date
AU70835/96A Abandoned AU7083596A (en) 1995-09-22 1996-09-20 Novel substituted azacyclic or azabicyclic compounds

Country Status (4)

Country Link
EP (1) EP0853621A1 (en)
JP (1) JPH11512443A (en)
AU (1) AU7083596A (en)
WO (1) WO1997011072A1 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4394897A (en) * 1996-10-30 1998-05-22 Pfizer Inc. Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and the ir use in addiction therapy
CA2289570C (en) * 1997-05-30 2007-04-03 Neurosearch A/S 9-azabicyclo(3.3.1)non-2-ene and nonane derivatives as cholinergic ligands at nicotinic ach receptors
DK0984965T3 (en) 1997-05-30 2004-09-27 Neurosearch As 8-azabicyclo [3.2.1] oct-2 end derivatives as cholinergic ligands at nicotine ACh receptors
AU736547B2 (en) 1997-05-30 2001-08-02 Neurosearch A/S Azacyclooctane and heptane derivatives, their preparation and use in therapy
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
UA66825C2 (en) * 1997-12-31 2004-06-15 Пфайзер Продактс Інк. Azapolycyclic compounds condensed with aryl
ATE240331T1 (en) * 1998-04-02 2003-05-15 Targacept Inc AZATRICYCLO(3.3.1.1) DECANDERIVATES AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME
US6432975B1 (en) 1998-12-11 2002-08-13 Targacept, Inc. Pharmaceutical compositions and methods for use
US6953855B2 (en) 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
FR2790474B1 (en) * 1999-03-05 2001-04-06 Synthelabo PYRIDOPYRANOAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
SE9903760D0 (en) * 1999-10-18 1999-10-18 Astra Ab New compounds
US6890935B2 (en) 1999-11-01 2005-05-10 Targacept, Inc. Pharmaceutical compositions and methods for use
US6852721B2 (en) 2000-05-25 2005-02-08 Targacept, Inc. Pharmaceutical compositions and methods for use
US6579878B1 (en) 2000-07-07 2003-06-17 Targacept, Inc. Pharmaceutical compositions and methods for use
US6624167B1 (en) 2000-08-04 2003-09-23 Targacept, Inc. Pharmaceutical compositions and methods for use
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
PE20060437A1 (en) 2004-06-18 2006-06-08 Novartis Ag AZA-BICYCLONONE COMPOUNDS AS CHOLINERGIC LINKS OF nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
EP1802258A4 (en) 2004-09-13 2015-09-23 Chrono Therapeutics Inc Biosynchronous transdermal drug delivery
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
JP2010523587A (en) 2007-04-02 2010-07-15 パーキンソンズ インスティテュート Methods and compositions for reducing the side effects of therapeutic treatments
SA08290475B1 (en) 2007-08-02 2013-06-22 Targacept Inc (2S,3R)-N-(2-((3-Pyridinyl)Methyl)-1-Azabicyclo[2.2.2]Oct-3-yl)Benzofuran-2-Carboxamide, Novel Salt forms, and Methods of Use Thereof
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
GB0913318D0 (en) 2009-07-31 2009-09-02 Univ Loughborough Process
US10213586B2 (en) 2015-01-28 2019-02-26 Chrono Therapeutics Inc. Drug delivery methods and systems
US9724340B2 (en) 2015-07-31 2017-08-08 Attenua, Inc. Antitussive compositions and methods
EP3565617A1 (en) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
EP3801732A4 (en) 2018-05-29 2022-04-27 Morningside Venture Investments Limited Drug delivery methods and systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852279A (en) * 1973-03-12 1974-12-03 Squibb & Sons Inc 7-substituted -3,3a,4,5,6,7-hexahydro-3-substituted-2h- pyrazolo (4,3-c)pyridines
GB8917957D0 (en) * 1989-08-05 1989-09-20 Beecham Group Plc Novel compounds
JPH06239861A (en) * 1993-02-17 1994-08-30 Kanegafuchi Chem Ind Co Ltd Bicyclic nitrogen-containing compound

Also Published As

Publication number Publication date
EP0853621A1 (en) 1998-07-22
WO1997011072A1 (en) 1997-03-27
JPH11512443A (en) 1999-10-26

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