RS50197B - Novi tiotropiumski preparati- koji sadrže prah za inhaliranje - Google Patents
Novi tiotropiumski preparati- koji sadrže prah za inhaliranjeInfo
- Publication number
- RS50197B RS50197B YUP-363/02A YUP36302A RS50197B RS 50197 B RS50197 B RS 50197B YU P36302 A YUP36302 A YU P36302A RS 50197 B RS50197 B RS 50197B
- Authority
- RS
- Serbia
- Prior art keywords
- inhalation
- powder
- auxiliary substance
- tiotropium
- auxiliary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MEP-401/08A MEP40108A (en) | 2000-10-12 | 2001-09-28 | Novel tiotropium-containing inhalation powder |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10050635 | 2000-10-12 | ||
| PCT/EP2001/011227 WO2002030389A1 (de) | 2000-10-12 | 2001-09-28 | Neue tiotropium-haltige inhalationspulver |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU36302A YU36302A (sh) | 2002-09-19 |
| RS50197B true RS50197B (sr) | 2009-05-06 |
Family
ID=7659578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-363/02A RS50197B (sr) | 2000-10-12 | 2001-09-28 | Novi tiotropiumski preparati- koji sadrže prah za inhaliranje |
Country Status (48)
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02005666A (es) | 2000-10-12 | 2002-11-29 | Boehringer Ingelheim Pharma | Nuevos polvos para anhalacion que contienen tiotropio. |
| US8580306B2 (en) | 2000-11-30 | 2013-11-12 | Vectura Limited | Particles for use in a pharmaceutical composition |
| ES2708961T3 (es) | 2000-11-30 | 2019-04-12 | Vectura Ltd | Composiciones farmacéuticas para inhalación |
| US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
| DE10128779A1 (de) * | 2001-06-13 | 2003-01-02 | Boehringer Ingelheim Pharma | Verfahren zur Reinigung von Hartgelatinekapseln |
| US20030008001A1 (en) * | 2001-06-13 | 2003-01-09 | Boehringer Ingelheim Pharma Kg | Process for cleaning hard gelatine capsules |
| DE10141377A1 (de) | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
| DE10141376A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Inhalationspulvern |
| DE10212264A1 (de) | 2002-03-20 | 2003-10-02 | Boehringer Ingelheim Pharma | Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels |
| US7309707B2 (en) * | 2002-03-20 | 2007-12-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament |
| US7244415B2 (en) * | 2002-03-28 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations of an anhydrate |
| ES2272968T3 (es) * | 2002-04-04 | 2007-05-01 | BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG | Formulaciones en polvo, adecuadas para inhalacion. |
| US20030235538A1 (en) * | 2002-04-09 | 2003-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for the administration of an anticholinergic by inhalation |
| CN1674918A (zh) * | 2002-06-12 | 2005-09-28 | 埃匹吉尼斯医药有限公司 | 利用脱氢表雄酮甾体及抗毒蕈碱药物治疗呼吸道疾病及肺病的组合物、制剂和试剂盒 |
| JP2006516531A (ja) * | 2002-08-21 | 2006-07-06 | ノートン ヘルスケアー リミテッド | 吸入組成物 |
| GB0219511D0 (en) * | 2002-08-21 | 2002-10-02 | Norton Healthcare Ltd | Method of preparing dry powder inhalation compositions |
| GB0219513D0 (en) | 2002-08-21 | 2002-10-02 | Norton Healthcare Ltd | Inhalation compositions including coarse carrier |
| AU2003269989B8 (en) * | 2002-08-21 | 2009-11-12 | Norton Healthcare Ltd. | Inhalation composition |
| DE10255387A1 (de) * | 2002-11-28 | 2004-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Tiotropium-haltige Pulverformulierung für die Inhalation |
| US7763280B2 (en) | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
| US20050058606A1 (en) * | 2002-12-16 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing HFC solution formulations |
| US20040152720A1 (en) * | 2002-12-20 | 2004-08-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powdered medicaments containing a tiotropium salt and salmeterol xinafoate |
| DE10317461A1 (de) | 2003-04-16 | 2004-10-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung |
| US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
| EP1635762B1 (en) * | 2003-06-13 | 2021-03-03 | Civitas Therapeutics, Inc. | Low dose pharmaceutical powders for inhalation |
| TWI359675B (en) * | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| US20050038004A1 (en) * | 2003-07-31 | 2005-02-17 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease |
| EP2322522A1 (de) | 2003-11-03 | 2011-05-18 | Boehringer Ingelheim International Gmbh | Neue Tiotropiumsalze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittelformulierungen |
| EP2336126A1 (de) | 2003-11-03 | 2011-06-22 | Boehringer Ingelheim International GmbH | Tiotropiumsalze, Verfahren zu deren Herstellung und Arzneimittelformulierungen diese enthaltend |
| SE0303270L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Metod för administration av tiotropium |
| SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
| WO2005053648A1 (en) * | 2003-12-03 | 2005-06-16 | Microdrug Ag | Pre-metered dry powder inhaler for moisture-sensitive medicaments |
| AU2004294889B2 (en) * | 2003-12-03 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Medical product containing tiotropium |
| SE0303269L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
| DE102004048389A1 (de) | 2004-10-01 | 2006-04-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa |
| RU2007133547A (ru) | 2005-02-10 | 2009-03-20 | Глаксо Груп Лимитед (GB) | Способы получения лактозы с использованием методов предварительной сортировки и приготовляемые из нее фармацевтические композиции |
| PL1881980T3 (pl) * | 2005-05-02 | 2013-01-31 | Boehringer Ingelheim Int | Nowe krystaliczne formy bromku tiotropium |
| RU2418796C2 (ru) * | 2005-06-15 | 2011-05-20 | Берингер Ингельхайм Интернациональ Гмбх | Способ получения новых солей тиотропия |
| TWI274641B (en) * | 2005-08-30 | 2007-03-01 | Rexon Ind Corp Ltd | Cutting machine |
| KR101395881B1 (ko) * | 2005-12-19 | 2014-05-21 | 시코르, 인크. | 브롬화 티오트로피움의 신규한 형태 및 이의 제조 방법 |
| RU2453547C2 (ru) * | 2005-12-19 | 2012-06-20 | Сикор Инк. | Новые формы тиотропия бромида и способы их получения |
| US9108962B2 (en) | 2005-12-19 | 2015-08-18 | Sicor, Inc. | Forms of tiotropium bromide and processes for preparation thereof |
| CN101360744A (zh) * | 2005-12-19 | 2009-02-04 | 西科尔公司 | 纯和稳定的噻托溴铵 |
| US20070167480A1 (en) * | 2005-12-19 | 2007-07-19 | Sicor Inc. | Pure and stable tiotropium bromide |
| US20080051582A1 (en) * | 2006-07-10 | 2008-02-28 | Sicor Inc. | Process for the preparation of tiotropium bromide |
| GB0716026D0 (en) * | 2007-08-16 | 2007-09-26 | Norton Healthcare Ltd | An inhalable medicament |
| RU2479587C2 (ru) * | 2007-07-27 | 2013-04-20 | Карджилл, Инкорпорейтед | Микронизация полиолов |
| US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
| CN102014779B (zh) | 2008-05-09 | 2014-10-22 | 赫莱拉公司 | 用于治疗支气管树的系统、组件和方法 |
| EP2172190A1 (en) | 2008-10-02 | 2010-04-07 | Laboratorios Liconsa, S.A. | Inhalable particles comprising tiotropium |
| CA2755697A1 (en) | 2009-03-17 | 2010-09-23 | Daiichi Sankyo Company, Limited | Amide derivative |
| CN104856757B (zh) | 2009-10-27 | 2017-06-23 | 赫莱拉公司 | 具有可冷却的能量发射组件的递送装置 |
| US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
| AU2010319477A1 (en) | 2009-11-11 | 2012-05-24 | Holaira, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
| US8834931B2 (en) | 2009-12-25 | 2014-09-16 | Mahmut Bilgic | Dry powder formulation containing tiotropium for inhalation |
| WO2011152804A2 (en) * | 2010-06-03 | 2011-12-08 | Mahmut Bilgic | Process for dry powder formulations |
| TR201007251A2 (tr) * | 2010-09-01 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Kalsiyum kanal blokörü formülasyonu. |
| GB201200525D0 (en) | 2011-12-19 | 2012-02-29 | Teva Branded Pharmaceutical Prod R & D Inc | An inhalable medicament |
| WO2014007773A1 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Compositions comprising muscarinic receptor antagonist and sorbitol |
| JP6335798B2 (ja) | 2012-02-28 | 2018-05-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規噴射剤含有チオトロピウム製剤 |
| RU2522213C2 (ru) * | 2012-06-07 | 2014-07-10 | Шолекс Девелопмент Гмбх, | Фармацевтический ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких, содержащих в качестве активного вещества микронизированный тиотропия бромид, и способ его получения |
| WO2014007781A2 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions |
| US10111957B2 (en) | 2012-07-05 | 2018-10-30 | Arven Ilac Snayi ve Ticaret A.S. | Inhalation compositions comprising glucose anhydrous |
| EA036153B1 (ru) | 2012-07-05 | 2020-10-06 | Арвен Айлак Санайи Ве Тиджарет А.С. | Фармацевтическая композиция для ингаляции, упакованная дозированная форма, капсула, способ лечения обструктивных заболеваний дыхательных путей и фармацевтический набор |
| WO2014007771A2 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising muscarinic receptor antagonist |
| WO2014007770A2 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising corticosteroid and sorbitol |
| US20150174064A1 (en) * | 2012-07-05 | 2015-06-25 | Arven IIac Sanayi Ve Ticaret A.S. | Compositions comprising muscarinic receptor antagonist and glucose anhydrous |
| EP2705838A1 (en) * | 2012-09-06 | 2014-03-12 | Xspray Microparticles Ab | Tiotropium preparations |
| US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
| WO2015065222A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Фармацевтический ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких, содержащий в качестве активного вещества микронизированный тиотропия бромид, и способ его получения |
| EP2913332A1 (en) | 2014-02-27 | 2015-09-02 | Euticals S.P.A. | Crystalline form of tiotropium bromide with lactose |
| US10034866B2 (en) | 2014-06-19 | 2018-07-31 | Teva Branded Pharmaceutical Products R&D, Inc. | Inhalable medicament comprising tiotropium |
| BR112018008083A2 (pt) | 2015-10-23 | 2018-10-23 | Arven Ilac Sanayi Ve Ticaret As | blister para formulação inalável de brometo de tiotrópio |
| KR101728116B1 (ko) * | 2015-11-03 | 2017-04-18 | 한미약품 주식회사 | 티오트로피움 또는 이의 약학적으로 허용가능한 염을 함유하는 흡입용 건조분말 조성물 |
| MX386252B (es) | 2015-12-24 | 2025-03-18 | Philip Morris Products Sa | Polvo de nicotina saborizada. |
| CN110505876A (zh) | 2017-03-23 | 2019-11-26 | 新加坡保健服务集团 | 包含噻托铵作为活性成分的用于预防近视、治疗近视、及/或预防近视进展的药剂 |
| EP4108230A1 (en) | 2021-06-24 | 2022-12-28 | Laboratoires SMB | New dry powder composition of tiotropium for inhalation |
| GR1010358B (el) * | 2021-09-14 | 2022-12-16 | Elpen Ανωνυμος Εταιρεια Φαρμακευτικη Βιομηχανια, | Σταθερο φαρμακευτικο σκευασμα που περιεχει βρωμιουχο τιοτροπιο, για χορηγηση απο το αναπνευστικο |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1242211A (en) * | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
| US3860618A (en) * | 1967-08-08 | 1975-01-14 | Philip Saxton Hartley | Chromone |
| US3957965A (en) * | 1967-08-08 | 1976-05-18 | Fisons Limited | Sodium chromoglycate inhalation medicament |
| DE2540633A1 (de) * | 1975-09-12 | 1977-04-28 | Boehringer Sohn Ingelheim | Neue quartaere n-beta-substituierte benzilsaeure-n-alkyl-nortropinester und verfahren zu deren herstellung |
| DE3211185A1 (de) * | 1982-03-26 | 1983-09-29 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue quartaere 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkyl- norscopinether und verfahren zu deren herstellung |
| DE3215493A1 (de) * | 1982-04-26 | 1983-11-03 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue zwischenprodukte, verfahren zu ihrer herstellung und ihre verwendung |
| JPS60172442A (ja) | 1984-02-20 | 1985-09-05 | Fanuc Ltd | ならい加工およびνｃ加工による機械加工装置 |
| US5610163A (en) * | 1989-09-16 | 1997-03-11 | Boehringer Ingelheim Gmbh | Esters of thienyl carboxylic acids and amino alcohols and their quaternization products |
| DE3931041C2 (de) | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DE4108393A1 (de) * | 1991-03-15 | 1992-09-17 | Boehringer Ingelheim Kg | Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln |
| DE69226950T2 (de) * | 1991-04-08 | 1999-05-12 | Nippon Shinyaku Co., Ltd., Kyoto | Kapsel mit Langzeitwirkung fuer die Adhäsion im Gastrointestinaltrakt |
| DE4140689B4 (de) * | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalationspulver und Verfahren zu ihrer Herstellung |
| US5770738A (en) * | 1992-03-05 | 1998-06-23 | Boehringer Ingelheim Kg | Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions |
| DE4318455A1 (de) * | 1993-06-03 | 1994-12-08 | Boehringer Ingelheim Kg | Kapselhalterung |
| GB9311892D0 (en) | 1993-06-09 | 1993-07-28 | Glaxo Wellcome Australia Ltd | Device |
| DE69426408T2 (de) * | 1993-09-28 | 2001-07-12 | Novartis Ag, Basel | Herstellung von Weichgelatinekapseln |
| GB9322014D0 (en) * | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
| GB9404945D0 (en) * | 1994-03-15 | 1994-04-27 | Glaxo Group Ltd | Pharmaceutical composition |
| DE4425255A1 (de) | 1994-07-16 | 1996-01-18 | Asta Medica Ag | Formulierung zur inhalativen Applikation |
| DE19515625C2 (de) * | 1995-04-28 | 1998-02-19 | Boehringer Ingelheim Kg | Verfahren zur Herstellung von enantiomerenreinen Tropasäureestern |
| FR2757173A1 (fr) * | 1996-12-17 | 1998-06-19 | Warner Lambert Co | Compositions polymeres d'origine non-animale pour la formation de films |
| US6228394B1 (en) * | 1997-10-14 | 2001-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Supercritical fluid extraction of mould lubricant from hard shell capsules |
| US6235725B1 (en) * | 1998-10-30 | 2001-05-22 | Baker Norton Pharmaceuticals, Inc. | Methods and compositions for the prevention of tolerance to medications |
| NZ511527A (en) * | 1998-11-13 | 2002-10-25 | Jago Res A | Dry powder for inhalation |
| GB9902689D0 (en) * | 1999-02-08 | 1999-03-31 | Novartis Ag | Organic compounds |
| US20040002548A1 (en) * | 1999-05-12 | 2004-01-01 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
| JP3931486B2 (ja) * | 1999-06-24 | 2007-06-13 | 住友化学株式会社 | ポジ型レジスト組成物 |
| MXPA02005666A (es) * | 2000-10-12 | 2002-11-29 | Boehringer Ingelheim Pharma | Nuevos polvos para anhalacion que contienen tiotropio. |
| UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| US6908928B2 (en) * | 2000-10-12 | 2005-06-21 | Bi Pharma Kg. | Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions |
| DE10064816A1 (de) * | 2000-12-22 | 2002-06-27 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung eines Anticholinergikums |
| US6506900B1 (en) * | 2001-01-31 | 2003-01-14 | Boehringer Ingelheim Pharma Ag | Process for preparing a scopine ester intermediate |
| DE10126924A1 (de) | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalationskapseln |
| US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
| US6482429B1 (en) * | 2001-06-20 | 2002-11-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Stable powder inhalation dosage formulation |
| DE10141376A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Inhalationspulvern |
| DE10141377A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
| US7309707B2 (en) * | 2002-03-20 | 2007-12-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament |
| ES2272968T3 (es) | 2002-04-04 | 2007-05-01 | BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG | Formulaciones en polvo, adecuadas para inhalacion. |
| US20030235538A1 (en) * | 2002-04-09 | 2003-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for the administration of an anticholinergic by inhalation |
| UA80123C2 (en) | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
| US7763280B2 (en) * | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
-
2001
- 2001-09-28 MX MXPA02005666A patent/MXPA02005666A/es active IP Right Grant
- 2001-09-28 PL PL356840A patent/PL200063B1/pl unknown
- 2001-09-28 HU HU0203885A patent/HU226982B1/hu unknown
- 2001-09-28 BR BR0107304-4A patent/BR0107304A/pt not_active Application Discontinuation
- 2001-09-28 DE DE50103551.6T patent/DE50103551C5/de not_active Expired - Lifetime
- 2001-09-28 AP APAP/P/2003/002774A patent/AP1712A/en active
- 2001-09-28 ME MEP-2008-401A patent/ME00245B/me unknown
- 2001-09-28 EE EEP200200428A patent/EE04414B1/xx unknown
- 2001-09-28 EA EA200200551A patent/EA004034B1/ru not_active IP Right Cessation
- 2001-09-28 CA CA002395653A patent/CA2395653C/en not_active Expired - Lifetime
- 2001-09-28 PT PT01969789T patent/PT1292281E/pt unknown
- 2001-09-28 ES ES01969789T patent/ES2227268T3/es not_active Expired - Lifetime
- 2001-09-28 HR HR20020437A patent/HRP20020437B1/xx not_active IP Right Cessation
- 2001-09-28 SI SI200130160T patent/SI1292281T1/xx unknown
- 2001-09-28 EP EP01969789A patent/EP1292281B1/de not_active Expired - Lifetime
- 2001-09-28 AU AU89935/01A patent/AU757008B2/en not_active Expired
- 2001-09-28 AT AT01969789T patent/ATE275391T1/de active
- 2001-09-28 KR KR10-2002-7007877A patent/KR100488644B1/ko not_active Expired - Lifetime
- 2001-09-28 SK SK706-2002A patent/SK285389B6/sk not_active IP Right Cessation
- 2001-09-28 CN CNB01803098XA patent/CN1210017C/zh not_active Ceased
- 2001-09-28 OA OA1200300108A patent/OA12522A/fr unknown
- 2001-09-28 DK DK01969789T patent/DK1292281T3/da active
- 2001-09-28 DZ DZ013477A patent/DZ3477A1/xx active
- 2001-09-28 TR TR2004/02367T patent/TR200402367T4/xx unknown
- 2001-09-28 GE GE5215A patent/GEP20063865B/en unknown
- 2001-09-28 WO PCT/EP2001/011227 patent/WO2002030389A1/de not_active Ceased
- 2001-09-28 ME MEP-401/08A patent/MEP40108A/xx unknown
- 2001-09-28 RS YUP-363/02A patent/RS50197B/sr unknown
- 2001-09-28 CZ CZ20021785A patent/CZ301465B6/cs not_active IP Right Cessation
- 2001-09-28 EP EP04006349A patent/EP1430887A1/de not_active Withdrawn
- 2001-09-28 JP JP2002533832A patent/JP3870159B2/ja not_active Expired - Lifetime
- 2001-09-28 UA UA2002064932A patent/UA72014C2/uk unknown
- 2001-09-28 IL IL14998401A patent/IL149984A0/xx active IP Right Grant
- 2001-09-28 NZ NZ519406A patent/NZ519406A/en not_active IP Right Cessation
- 2001-10-09 EG EG20011059A patent/EG24139A/xx active
- 2001-10-09 TW TW090124971A patent/TWI285553B/zh not_active IP Right Cessation
- 2001-10-10 UY UY26959A patent/UY26959A1/es not_active IP Right Cessation
- 2001-10-10 PE PE2001001001A patent/PE20020577A1/es active IP Right Grant
- 2001-10-10 MY MYPI20014706A patent/MY123544A/en unknown
- 2001-10-11 US US09/975,418 patent/US7070800B2/en not_active Expired - Lifetime
- 2001-10-12 AR ARP010104783A patent/AR031819A1/es not_active Application Discontinuation
- 2001-10-15 SA SA01220460A patent/SA01220460B1/ar unknown
-
2002
- 2002-05-21 ZA ZA200204378A patent/ZA200204378B/xx unknown
- 2002-05-21 BG BG106730A patent/BG65753B1/bg unknown
- 2002-05-22 NO NO20022414A patent/NO331956B1/no not_active IP Right Cessation
- 2002-05-28 EC EC2002004268A patent/ECSP024268A/es unknown
- 2002-06-03 IL IL149984A patent/IL149984A/en unknown
-
2003
- 2003-03-26 CR CR6937A patent/CR6937A/es not_active Application Discontinuation
- 2003-04-08 EC EC2003004546A patent/ECSP034546A/es unknown
- 2003-04-08 IS IS6771A patent/IS2360B/is unknown
- 2003-04-08 MA MA27103A patent/MA25843A1/fr unknown
- 2003-04-11 CU CU20030082A patent/CU23284B7/es unknown
- 2003-12-05 US US10/729,543 patent/US20040228806A1/en not_active Abandoned
-
2005
- 2005-10-20 US US11/254,573 patent/US20060039868A1/en not_active Abandoned
-
2008
- 2008-07-29 US US12/181,651 patent/US20080292563A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RS50197B (sr) | Novi tiotropiumski preparati- koji sadrže prah za inhaliranje | |
| JP4331619B2 (ja) | 臭化チオトロピウムの結晶性微粒子 | |
| RS50353B (sr) | Inhalacione kapsule | |
| KR101007151B1 (ko) | 흡입용 분말 제형 | |
| RS20050400A (sr) | Nove formulacije praha za inhaliranje koje sadrže tiotropijum | |
| HK1078795B (en) | Powder formulations suitable for inhalation |