RS49929B - Referentno jedinjenje za upotrebu u analizi šarži levosimendana - Google Patents

Referentno jedinjenje za upotrebu u analizi šarži levosimendana

Info

Publication number
RS49929B
RS49929B YUP-767/00A YU76700A RS49929B RS 49929 B RS49929 B RS 49929B YU 76700 A YU76700 A YU 76700A RS 49929 B RS49929 B RS 49929B
Authority
RS
Serbia
Prior art keywords
analysis
reference compound
levosimendan
batches
levosimendan batches
Prior art date
Application number
YUP-767/00A
Other languages
English (en)
Inventor
Reijo Backstrom
Aho Tuula Hauta
Tuula Heinonen
Original Assignee
Orion Corporation,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation, filed Critical Orion Corporation,
Publication of YU76700A publication Critical patent/YU76700A/sh
Publication of RS49929B publication Critical patent/RS49929B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N2030/042—Standards
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]

Abstract

Jedinjenje, naznačeno time, što ima strukturnu fomulu I i njegovi diastereoizomeri. Prijava sadrži još 8 patentnih zahteva. (I)
YUP-767/00A 1998-06-18 1999-06-18 Referentno jedinjenje za upotrebu u analizi šarži levosimendana RS49929B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI981428A FI104718B (fi) 1998-06-18 1998-06-18 [[4-(2-atsido-3-metyyli-5-oksotetrahydrofuran-2-yyli)fenyyli]hydratsono]propaanidinitriili käytettäväksi referenssiaineena levosimendaanierien analyysissä

Publications (2)

Publication Number Publication Date
YU76700A YU76700A (sh) 2002-11-15
RS49929B true RS49929B (sr) 2008-09-29

Family

ID=8552039

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-767/00A RS49929B (sr) 1998-06-18 1999-06-18 Referentno jedinjenje za upotrebu u analizi šarži levosimendana

Country Status (28)

Country Link
US (1) US6340764B1 (sr)
EP (1) EP1087956B1 (sr)
JP (1) JP4550279B2 (sr)
KR (1) KR100661772B1 (sr)
CN (1) CN1129590C (sr)
AR (1) AR018879A1 (sr)
AT (1) ATE253566T1 (sr)
AU (1) AU755699B2 (sr)
BR (1) BR9911230A (sr)
CA (1) CA2334864C (sr)
CZ (1) CZ298659B6 (sr)
DE (1) DE69912604D1 (sr)
EA (1) EA002854B1 (sr)
ES (1) ES2211113T3 (sr)
FI (1) FI104718B (sr)
HK (1) HK1032779A1 (sr)
HR (1) HRP20000866B1 (sr)
HU (1) HU229582B1 (sr)
ID (1) ID29239A (sr)
IL (1) IL139964A (sr)
MX (1) MXPA00012436A (sr)
NO (1) NO325393B1 (sr)
NZ (1) NZ508557A (sr)
PL (1) PL201772B1 (sr)
RS (1) RS49929B (sr)
SK (1) SK284353B6 (sr)
WO (1) WO1999065888A2 (sr)
ZA (1) ZA200006993B (sr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532686A (ja) 2004-04-21 2007-11-15 テバ ファーマシューティカル インダストリーズ リミティド モンテルカストナトリウムを調製する方法
FR2877013A1 (fr) * 2004-10-27 2006-04-28 Assist Publ Hopitaux De Paris Indentification d'une mutation de jak2 impliquee dans la polyglobulie de vaquez
JP2008510840A (ja) 2005-07-05 2008-04-10 テバ ファーマシューティカル インダストリーズ リミティド モンテルカストの精製
CN104230816B (zh) * 2014-09-19 2017-02-15 成都新恒创药业有限公司 一种左西孟旦潜在基因毒性杂质及其制备、检测方法
CN104478809B (zh) * 2014-11-14 2016-08-17 成都新恒创药业有限公司 一种左西孟旦杂质及其制备和检测方法
CN105817632A (zh) * 2015-01-09 2016-08-03 中国科学院宁波材料技术与工程研究所 片状粉末的制备装置及方法
CN105784895B (zh) * 2015-10-30 2018-05-22 成都欣捷高新技术开发有限公司 一种用高效液相色谱仪检测左西孟旦中杂质的方法
CN111474289A (zh) * 2019-10-31 2020-07-31 武汉嘉诺康医药技术有限公司 一种利用反相色谱分离分析左西孟旦中右西孟旦的方法
CA3161960A1 (en) 2019-12-16 2021-06-24 Tenax Therapeutics, Inc. Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB383449A (en) * 1931-12-12 1932-11-17 Percy Charles Barton Improvements relating to masts, poles, or like supports and their manufacture
GB565546A (en) * 1943-04-13 1944-11-15 Leslie Frederick Reeve A pneumatically operated pickup unit for use in electric organs and the like
FI894035A (fi) 1988-09-07 1990-03-08 Orion Yhtymae Oy Foerfarande foer framstaellning av nya substituerade pyridazinoner.
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) * 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
GB9606474D0 (en) 1996-03-27 1996-06-05 Orion Yhytmo Oy Method for obtaining pure enantiomers of a pyridazinone derivative
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
GB9915179D0 (en) * 1999-06-29 1999-09-01 Orion Corp A method for the treatment or prevention of coronary graft vasospasm

Also Published As

Publication number Publication date
NO325393B1 (no) 2008-04-21
FI981428A0 (fi) 1998-06-18
WO1999065888A2 (en) 1999-12-23
CA2334864C (en) 2008-01-15
JP2002518383A (ja) 2002-06-25
IL139964A0 (en) 2002-02-10
EP1087956B1 (en) 2003-11-05
ATE253566T1 (de) 2003-11-15
CZ20004555A3 (en) 2001-05-16
AU4786399A (en) 2000-01-05
US6340764B1 (en) 2002-01-22
WO1999065888A3 (en) 2000-01-27
SK284353B6 (sk) 2005-02-04
BR9911230A (pt) 2001-03-06
HUP0102020A3 (en) 2002-04-29
EP1087956A2 (en) 2001-04-04
NZ508557A (en) 2002-05-31
MXPA00012436A (es) 2002-06-04
HUP0102020A2 (hu) 2001-12-28
SK18722000A3 (sk) 2001-09-11
DE69912604D1 (de) 2003-12-11
PL201772B1 (pl) 2009-05-29
CA2334864A1 (en) 1999-12-23
IL139964A (en) 2003-07-06
EA002854B1 (ru) 2002-10-31
ES2211113T3 (es) 2004-07-01
KR20010072622A (ko) 2001-07-31
HK1032779A1 (en) 2001-08-03
ID29239A (id) 2001-08-16
KR100661772B1 (ko) 2006-12-28
AU755699B2 (en) 2002-12-19
CN1129590C (zh) 2003-12-03
NO20006444L (no) 2000-12-15
FI981428A (fi) 1999-12-19
CZ298659B6 (cs) 2007-12-12
YU76700A (sh) 2002-11-15
AR018879A1 (es) 2001-12-12
ZA200006993B (en) 2002-02-28
HU229582B1 (en) 2014-02-28
CN1306527A (zh) 2001-08-01
FI104718B (fi) 2000-03-31
EA200100055A1 (ru) 2001-06-25
JP4550279B2 (ja) 2010-09-22
HRP20000866B1 (en) 2009-02-28
PL347577A1 (en) 2002-04-08
NO20006444D0 (no) 2000-12-15
HRP20000866A2 (en) 2001-12-31

Similar Documents

Publication Publication Date Title
TR199501656A2 (tr) Kimyasal bilesenler.
NO20004626D0 (no) Bicyclo(2.2.1)heptaner og beslektede forbindelser
ES2175066T3 (es) Antagonistas triciclicos de la vasopresina.
RS50005B (sr) Novi oblik s-omeprazola
ID18189A (id) Dervat-derivat 6,6-hetero-bisiklik yang disubstitusi
ATE221887T1 (de) Substituierte 1,2,4-triazolo(3,4,-a)phthalazin- derivate als gaba-alpha 5-liganden
MY124487A (en) Dolastatin derivatives, their preparation and use
IS4963A (is) Setnar 6,5-heteró-bísýklískar afleiður
FI916165A0 (fi) 1,3-oxatiolannukleosidanaloger.
MX9102462A (es) Amplificador orientado dinamicamente.
DE69221506T2 (de) Bildunterstützter elektronischer taschenorganisator.
PT984778E (pt) Ligandos do neuropeptido y
FI902190A0 (fi) Anordning foer framstaellning av heta drycker i en mikrovaogsugn.
DE68902400T2 (de) Harte ueberzugsmittel.
KR970002468A (ko) 화학증폭형 포지티브 레지스트 조성물
TR27961A (tr) Sübstitüe edilmis 1,2,3,4 -tetrahidro-5-nitro-pirimidinler.
MA23778A1 (fr) Purine-6-ones-2,9 disubstituees
ID21413A (id) Turunan-turunan 1,3,8,-triaza-spiro (4,5) dekan-4-on
FR2717697B1 (fr) Instrument d'implantation.
DE69003121D1 (de) Filmbildendes Mittel.
RS49929B (sr) Referentno jedinjenje za upotrebu u analizi šarži levosimendana
DE69427286D1 (de) 7,42-bis (o-demethyl)rapamycin
TR199901386T2 (en) �midazopiridazinler.
TR199701298T1 (xx) Tetralinler.
DE69107742D1 (de) Substituierte 3,7,9-Trioxa-1-aza-2,8-diphosphaspiro[4.5]dekane und stabilisierte Zusammensetzungen.