MA23778A1 - Purine-6-ones-2,9 disubstituees - Google Patents

Purine-6-ones-2,9 disubstituees

Info

Publication number
MA23778A1
MA23778A1 MA24133A MA24133A MA23778A1 MA 23778 A1 MA23778 A1 MA 23778A1 MA 24133 A MA24133 A MA 24133A MA 24133 A MA24133 A MA 24133A MA 23778 A1 MA23778 A1 MA 23778A1
Authority
MA
Morocco
Prior art keywords
disubstituted
purine
ones
Prior art date
Application number
MA24133A
Other languages
English (en)
Inventor
Bischoff Erwin
Niewohner Ulrich
Schutz Helmuth
Perzborn Elisabeth
Schramm Matthias
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MA23778A1 publication Critical patent/MA23778A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA24133A 1995-01-19 1996-01-18 Purine-6-ones-2,9 disubstituees MA23778A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19501482A DE19501482A1 (de) 1995-01-19 1995-01-19 2,9-disubstituierte Purin-6-one

Publications (1)

Publication Number Publication Date
MA23778A1 true MA23778A1 (fr) 1996-10-01

Family

ID=7751830

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24133A MA23778A1 (fr) 1995-01-19 1996-01-18 Purine-6-ones-2,9 disubstituees

Country Status (31)

Country Link
US (1) US5861404A (fr)
EP (1) EP0722944A1 (fr)
JP (1) JPH08231545A (fr)
KR (1) KR960029334A (fr)
CN (1) CN1135485A (fr)
AR (1) AR002953A1 (fr)
AU (1) AU4097996A (fr)
BG (1) BG61728B1 (fr)
BR (1) BR9600147A (fr)
CA (1) CA2167353A1 (fr)
CO (1) CO4700523A1 (fr)
CZ (1) CZ16696A3 (fr)
DE (1) DE19501482A1 (fr)
EE (1) EE9600018A (fr)
FI (1) FI960225A (fr)
HR (1) HRP960007A2 (fr)
HU (1) HUP9600106A3 (fr)
IL (1) IL116769A (fr)
MA (1) MA23778A1 (fr)
NO (1) NO960223L (fr)
NZ (1) NZ280830A (fr)
PE (1) PE64996A1 (fr)
PL (1) PL312354A1 (fr)
SG (1) SG50401A1 (fr)
SK (1) SK8096A3 (fr)
SV (1) SV1996000006A (fr)
TN (2) TNSN96007A1 (fr)
TR (1) TR199600028A2 (fr)
TW (1) TW314519B (fr)
YU (1) YU1396A (fr)
ZA (1) ZA96398B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19529102A1 (de) * 1995-08-08 1997-02-13 Kummer Horst Dieter Verwendung von PDE-Inhibitoren bei der Behandlung von Harnblasenerkrankungen
US5824669A (en) 1996-03-22 1998-10-20 Nitromed, Inc. Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
USRE37234E1 (en) 1996-11-01 2001-06-19 Nitromed, Inc. Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
US5958926A (en) 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
KR20010021905A (ko) * 1997-07-15 2001-03-15 노미야마 아키히콰 신규인 푸린유도체 및 그 의약용도
KR100540046B1 (ko) * 1997-11-12 2006-01-10 미쓰비시 가가꾸 가부시키가이샤 퓨린유도체 및 이를 유효성분으로 함유하는 의약
WO1999035147A1 (fr) * 1998-01-05 1999-07-15 Eisai Co., Ltd. Derives de purine et antagonistes du recepteur a2 d'adenosine utiles comme moyens de prevention/traitement du diabete
US6124303A (en) * 1998-09-11 2000-09-26 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 9-substituted 2-(2-N-aloxyphenyl) purin-6-ones
US6268372B1 (en) 1998-09-11 2001-07-31 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 2,9-disubstituted purin-6-ones
EP1178046B1 (fr) * 1999-05-11 2003-11-19 Mitsubishi Chemical Corporation Dihydrate derive de purine, medicaments le contenant comme principe actif et intermediaire utilise dans sa preparation
GB9924020D0 (en) 1999-10-11 1999-12-15 Pfizer Ltd Pharmaceutically active compounds
MXPA03001958A (es) * 2000-09-06 2003-06-24 Tanabe Seiyaku Co Preparaciones para administrar oral.
ATE472319T1 (de) * 2001-02-15 2010-07-15 Mitsubishi Tanabe Pharma Corp Tabletten, die in der mundhöhle schnell zerfallen
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes
US7208516B2 (en) 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7276529B2 (en) 2002-03-20 2007-10-02 Celgene Corporation Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
CN102742513A (zh) * 2012-07-17 2012-10-24 南京熊猫机电制造有限公司 一种喂食栏装置
MX2016014384A (es) 2014-06-23 2017-01-20 Celgene Corp Apremilast para el tratamiento de una enfermedad del higado o una anormalidad en la funcion del higado.
JP2022522534A (ja) 2019-04-02 2022-04-19 アリゴス セラピューティクス インコーポレイテッド Ｐｒｍｔ５を標的にする化合物
JP7385467B2 (ja) * 2019-12-26 2023-11-22 キッセイ薬品工業株式会社 ヒポキサンチン化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451478A (en) * 1982-03-12 1984-05-29 Newport Pharmaceuticals International, Inc. Imidazole compounds
IL76546A (en) * 1984-10-12 1988-12-30 Warner Lambert Co 9-(heteroarylalkyl)-6-purine(thi)one derivatives,their preparation and pharmaceutical compositions containing them
GB9213623D0 (en) * 1992-06-26 1992-08-12 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
AR002953A1 (es) 1998-05-27
NZ280830A (en) 1998-04-27
HRP960007A2 (en) 1998-02-28
IL116769A (en) 1998-12-06
PL312354A1 (en) 1996-07-22
NO960223D0 (no) 1996-01-18
DE19501482A1 (de) 1996-07-25
BR9600147A (pt) 1998-01-06
HUP9600106A3 (en) 1998-04-28
KR960029334A (ko) 1996-08-17
TR199600028A2 (tr) 1996-08-21
JPH08231545A (ja) 1996-09-10
YU1396A (sh) 1999-03-04
TNSN96007A1 (fr) 2005-03-15
EP0722944A1 (fr) 1996-07-24
AU4097996A (en) 1996-07-25
HUP9600106A2 (en) 1997-05-28
TNSN96006A1 (fr) 2005-03-15
SK8096A3 (en) 1996-08-07
CA2167353A1 (fr) 1996-07-20
CZ16696A3 (en) 1996-08-14
CN1135485A (zh) 1996-11-13
ZA96398B (en) 1996-08-28
BG61728B1 (bg) 1998-04-30
TW314519B (fr) 1997-09-01
US5861404A (en) 1999-01-19
BG100292A (bg) 1996-07-31
CO4700523A1 (es) 1998-12-29
NO960223L (no) 1996-07-22
PE64996A1 (es) 1997-03-09
SG50401A1 (en) 1998-07-20
FI960225A0 (fi) 1996-01-17
FI960225A (fi) 1996-07-20
EE9600018A (et) 1996-08-15
HU9600106D0 (en) 1996-03-28
SV1996000006A (es) 1996-10-29
IL116769A0 (en) 1996-05-14

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