RS115104A - Pramipexole once-daily dosage form - Google Patents

Pramipexole once-daily dosage form

Info

Publication number
RS115104A
RS115104A RS115104A RSP510411A RS115104A RS 115104 A RS115104 A RS 115104A RS 115104 A RS115104 A RS 115104A RS P510411 A RSP510411 A RS P510411A RS 115104 A RS115104 A RS 115104A
Authority
RS
Serbia
Prior art keywords
pramipexole
hours
absorption
composition
mean
Prior art date
Application number
RS115104A
Other languages
English (en)
Inventor
Ernest Lee
Gerard Bredael
John Baldwin
Steven Cox
Mark Heintz
Original Assignee
Pharmacia Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31192088&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS115104(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Corporation filed Critical Pharmacia Corporation
Publication of RS115104A publication Critical patent/RS115104A/sr
Publication of RS52764B publication Critical patent/RS52764B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Oralno primenljiva farmaceutska kompozicija koja uključuje terapeutski efektivnu količinu pramipeksola ili njegove farmaceutski prihvatljive soli i najmanje jedan farmaceutski prihvatljiv ekscipijent, a navedena kompozicija pokazuje najmanje (a) profil in vitro oslobađanja, pri čemu je u proseku ne više od približno 20% pramipeksola rastvoreno u toku 2 sata nakon podvrgavanja kompozicije standardnom disolušn testu; i (b) profil in vivo apsorpcije pramipeksola nakon oralne primene pojedinačne doze na zdravim odraslim ljudima, pri čemu je vreme za dostizanje 20% apsorpcije u proseku veće od približno 2 sata i/ili vreme za postizanje 40% apsorpcije u proseku veće od približno 4 sata. Kompozicija je korisna za oralnu primenu, ne više od jedanput dnevno, na subjektu koji ima stanje ili oboljenje za koje je indikovan agonist dopamin receptora.
RS115104A 2002-07-25 2003-07-25 Dozirani oblik pramipeksola za upotrebu jedanput dnevno RS52764B (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39844702P 2002-07-25 2002-07-25
US39842702P 2002-07-25 2002-07-25
US47951403P 2003-06-18 2003-06-18
PCT/US2003/023522 WO2004010999A1 (en) 2002-07-25 2003-07-25 Pramipexole once-daily dosage form

Publications (2)

Publication Number Publication Date
RS115104A true RS115104A (en) 2006-12-15
RS52764B RS52764B (sr) 2013-10-31

Family

ID=31192088

Family Applications (1)

Application Number Title Priority Date Filing Date
RS115104A RS52764B (sr) 2002-07-25 2003-07-25 Dozirani oblik pramipeksola za upotrebu jedanput dnevno

Country Status (40)

Country Link
US (2) US8679533B2 (sr)
EP (2) EP2289514B9 (sr)
JP (1) JP4607584B2 (sr)
KR (2) KR20050025654A (sr)
CN (1) CN1671381B (sr)
AP (1) AP2223A (sr)
AR (1) AR040682A1 (sr)
AU (1) AU2003256921B2 (sr)
BR (1) BR0312948A (sr)
CA (1) CA2493629C (sr)
CU (1) CU23468B7 (sr)
CY (2) CY1114263T1 (sr)
DE (1) DE20321906U1 (sr)
DK (2) DK1536792T3 (sr)
EA (1) EA017595B1 (sr)
EC (1) ECSP055569A (sr)
ES (2) ES2421787T3 (sr)
GE (1) GEP20074047B (sr)
HK (1) HK1078007A1 (sr)
HR (1) HRP20041234B1 (sr)
IL (1) IL166076A0 (sr)
IS (1) IS7613A (sr)
MA (1) MA27372A1 (sr)
ME (1) ME00347B (sr)
MX (1) MXPA05000980A (sr)
MY (1) MY142204A (sr)
NO (1) NO20050481L (sr)
NZ (1) NZ562681A (sr)
OA (1) OA12889A (sr)
PA (1) PA8578501A1 (sr)
PE (1) PE20040134A1 (sr)
PL (1) PL375444A1 (sr)
PT (2) PT2289514E (sr)
RS (1) RS52764B (sr)
SG (1) SG177011A1 (sr)
SI (2) SI2289514T1 (sr)
TW (1) TWI351955B (sr)
UY (1) UY27913A1 (sr)
WO (1) WO2004010999A1 (sr)
ZA (1) ZA200500015B (sr)

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