ME00347B - Dozirani oblik pramipeksola za upotrebu jedanput dnevno - Google Patents
Dozirani oblik pramipeksola za upotrebu jedanput dnevnoInfo
- Publication number
- ME00347B ME00347B MEP-2008-522A MEP52208A ME00347B ME 00347 B ME00347 B ME 00347B ME P52208 A MEP52208 A ME P52208A ME 00347 B ME00347 B ME 00347B
- Authority
- ME
- Montenegro
- Prior art keywords
- pramipexole
- composition
- hours
- absorption
- approximately
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Oralno primenljiva farmaceutska kompozicija koja uključuje terapeutski efektivnu količinu pramipeksola ili njegove farmaceutski prihvaljive soli i najmanje jedan farmaceutski prihvatljiv ekscipijent, a navedena kompozicija pokazuje najmanje (a) profil in vitro oslobađanja, pri čemu je u proseku ne više od približno 20% pramipeksola rastvoreno u toku 2 sata nakon podvrgavanja kompozicije standardnom disolušn testu; i (b) profil in vivo apsorpcije pramipeksola nakon oralne primene pojedinačne doze na zdravim odrasljim ljudima, pri čemu je vreme za dostizanje 20%apsorpcije u proseku veće od približno 2 sata i/ili vreme za postizanje 40% apsorpcije u proseku veće od približno 4 sata. Kompozicija je korisna za oralnu primenu, ne više od jedanput dnevno, na subjektu koji ima stanje ili oboljenje za koje je indikovan agonist dopamin receptora.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39844702P | 2002-07-25 | 2002-07-25 | |
US39842702P | 2002-07-25 | 2002-07-25 | |
US47951403P | 2003-06-18 | 2003-06-18 | |
PCT/US2003/023522 WO2004010999A1 (en) | 2002-07-25 | 2003-07-25 | Pramipexole once-daily dosage form |
Publications (2)
Publication Number | Publication Date |
---|---|
MEP52208A MEP52208A (en) | 2011-02-10 |
ME00347B true ME00347B (me) | 2011-05-10 |
Family
ID=31192088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2008-522A ME00347B (me) | 2002-07-25 | 2003-07-25 | Dozirani oblik pramipeksola za upotrebu jedanput dnevno |
Country Status (40)
Country | Link |
---|---|
US (2) | US8679533B2 (me) |
EP (2) | EP1536792B1 (me) |
JP (1) | JP4607584B2 (me) |
KR (2) | KR20050025654A (me) |
CN (1) | CN1671381B (me) |
AP (1) | AP2223A (me) |
AR (1) | AR040682A1 (me) |
AU (1) | AU2003256921B2 (me) |
BR (1) | BR0312948A (me) |
CA (1) | CA2493629C (me) |
CU (1) | CU23468B7 (me) |
CY (2) | CY1114263T1 (me) |
DE (1) | DE20321906U1 (me) |
DK (2) | DK2289514T5 (me) |
EA (1) | EA017595B1 (me) |
EC (1) | ECSP055569A (me) |
ES (2) | ES2421787T3 (me) |
GE (1) | GEP20074047B (me) |
HK (1) | HK1078007A1 (me) |
HR (1) | HRP20041234B1 (me) |
IL (1) | IL166076A0 (me) |
IS (1) | IS7613A (me) |
MA (1) | MA27372A1 (me) |
ME (1) | ME00347B (me) |
MX (1) | MXPA05000980A (me) |
MY (1) | MY142204A (me) |
NO (1) | NO20050481L (me) |
NZ (1) | NZ562681A (me) |
OA (1) | OA12889A (me) |
PA (1) | PA8578501A1 (me) |
PE (1) | PE20040134A1 (me) |
PL (1) | PL375444A1 (me) |
PT (2) | PT1536792E (me) |
RS (1) | RS52764B (me) |
SG (1) | SG177011A1 (me) |
SI (2) | SI2289514T1 (me) |
TW (1) | TWI351955B (me) |
UY (1) | UY27913A1 (me) |
WO (1) | WO2004010999A1 (me) |
ZA (1) | ZA200500015B (me) |
Families Citing this family (44)
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CA2581282A1 (en) * | 2004-10-01 | 2006-04-13 | Nippon Zoki Pharmaceutical Co., Ltd. | Solid pharmaceutical preparation |
WO2006046256A1 (en) * | 2004-10-27 | 2006-05-04 | Alembic Limited | Extended release formulation of pramipexole dihydrochloride |
EP1988875A2 (en) * | 2006-02-10 | 2008-11-12 | Boehringer Ingelheim International GmbH | Modified release formulation |
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WO2007090882A2 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
US8518926B2 (en) * | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
DK2026803T3 (da) * | 2006-05-16 | 2012-04-16 | Knopp Neurosciences Inc | Sammensætninger af R(+) og S(-) pramipexol og fremgangsmåder til anvendelse heraf |
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CA2688074A1 (en) * | 2007-05-25 | 2008-12-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical formulation comprising pramipexole |
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AU2010234244A1 (en) * | 2009-04-09 | 2011-10-13 | Purdue Pharma | Once-daily oral IR/CR pramipexole formulation |
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WO2011086182A2 (en) * | 2010-01-18 | 2011-07-21 | Synthon Bv | Pramipexole extended release tablets |
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EP2575780A1 (en) | 2010-05-24 | 2013-04-10 | Lupin Limited | Extended release formulation of pramipexole |
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ES2858500T3 (es) | 2013-07-12 | 2021-09-30 | Knopp Biosciences Llc | Tratamiento de niveles elevados de eosinófilos y/o basófilos |
US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
AU2014306683B2 (en) | 2013-08-13 | 2017-10-12 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
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CN105030721B (zh) * | 2015-08-30 | 2018-05-04 | 南京康川济医药科技有限公司 | 一种含有盐酸普拉克索的口服固体组合物 |
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