DK2289514T3 - Pramipexol-doseringsform til anvendelse én gang dagligt - Google Patents

Pramipexol-doseringsform til anvendelse én gang dagligt

Info

Publication number
DK2289514T3
DK2289514T3 DK10174089.2T DK10174089T DK2289514T3 DK 2289514 T3 DK2289514 T3 DK 2289514T3 DK 10174089 T DK10174089 T DK 10174089T DK 2289514 T3 DK2289514 T3 DK 2289514T3
Authority
DK
Denmark
Prior art keywords
once
dosage form
daily use
pramipexole
pramipexole dosage
Prior art date
Application number
DK10174089.2T
Other languages
English (en)
Other versions
DK2289514T5 (da
Inventor
Ernest J Lee
Gerard M Bredael
John R Baldwin
Steven R Cox
Mark J Heintz
Original Assignee
Pharmacia Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31192088&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2289514(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Llc filed Critical Pharmacia Llc
Application granted granted Critical
Publication of DK2289514T3 publication Critical patent/DK2289514T3/da
Publication of DK2289514T5 publication Critical patent/DK2289514T5/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK10174089.2T 2002-07-25 2003-07-25 Pramipexol-doseringsform til anvendelse én gang dagligt DK2289514T5 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39844702P 2002-07-25 2002-07-25
US39842702P 2002-07-25 2002-07-25
US47951403P 2003-06-18 2003-06-18
EP03771959.8A EP1536792B1 (en) 2002-07-25 2003-07-25 Pramipexole once-daily dosage form

Publications (2)

Publication Number Publication Date
DK2289514T3 true DK2289514T3 (da) 2013-08-05
DK2289514T5 DK2289514T5 (da) 2013-09-30

Family

ID=31192088

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03771959.8T DK1536792T3 (da) 2002-07-25 2003-07-25 Pramipexol-doseringsform til anvendelse én gang dagligt
DK10174089.2T DK2289514T5 (da) 2002-07-25 2003-07-25 Pramipexol-doseringsform til anvendelse én gang dagligt

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03771959.8T DK1536792T3 (da) 2002-07-25 2003-07-25 Pramipexol-doseringsform til anvendelse én gang dagligt

Country Status (40)

Country Link
US (2) US8679533B2 (da)
EP (2) EP1536792B1 (da)
JP (1) JP4607584B2 (da)
KR (2) KR20050025654A (da)
CN (1) CN1671381B (da)
AP (1) AP2223A (da)
AR (1) AR040682A1 (da)
AU (1) AU2003256921B2 (da)
BR (1) BR0312948A (da)
CA (1) CA2493629C (da)
CU (1) CU23468B7 (da)
CY (2) CY1114263T1 (da)
DE (1) DE20321906U1 (da)
DK (2) DK1536792T3 (da)
EA (1) EA017595B1 (da)
EC (1) ECSP055569A (da)
ES (2) ES2421787T3 (da)
GE (1) GEP20074047B (da)
HK (1) HK1078007A1 (da)
HR (1) HRP20041234B1 (da)
IL (1) IL166076A0 (da)
IS (1) IS7613A (da)
MA (1) MA27372A1 (da)
ME (1) ME00347B (da)
MX (1) MXPA05000980A (da)
MY (1) MY142204A (da)
NO (1) NO20050481L (da)
NZ (1) NZ562681A (da)
OA (1) OA12889A (da)
PA (1) PA8578501A1 (da)
PE (1) PE20040134A1 (da)
PL (1) PL375444A1 (da)
PT (2) PT2289514E (da)
RS (1) RS52764B (da)
SG (1) SG177011A1 (da)
SI (2) SI1536792T1 (da)
TW (1) TWI351955B (da)
UY (1) UY27913A1 (da)
WO (1) WO2004010999A1 (da)
ZA (1) ZA200500015B (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
US7365086B2 (en) * 2003-07-25 2008-04-29 Synthon Ip Inc. Pramipexole acid addition salts
CN101843597A (zh) 2004-08-13 2010-09-29 贝林格尔·英格海姆国际有限公司 包含普拉克索或其可药用盐的延长释放小球制剂、其制备方法及其用途
SI1781260T2 (sl) * 2004-08-13 2014-08-29 Boehringer Ingelheim International Gmbh Tabletna formulacija s podaljšanim sproščanjem, ki vsebuje pramipeksol ali njegovo farmacevtsko sprejemljivo sol, postopek za izdelavo le-te in njena uporaba
US20080038344A1 (en) * 2004-10-01 2008-02-14 Nippon Zoki Pharmaceutical Co., Ltd. Solid Pharmaceutical Preparation
WO2006046256A1 (en) * 2004-10-27 2006-05-04 Alembic Limited Extended release formulation of pramipexole dihydrochloride
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
WO2007090882A2 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Pharmaceutical extended release compositions comprising pramipexole
WO2007090881A2 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Modified release formulation
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
JP2009537565A (ja) 2006-05-16 2009-10-29 ノップ ニューロサイエンシーズ、インク． Ｒ（＋）およびｓ（−）プラミペキソール組成とそれを利用する方法
US20080254118A1 (en) * 2007-04-11 2008-10-16 Hans-Werner Wernersbach Process for preparing pramipexole dihydrochloride tablets
US8524695B2 (en) * 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US10716798B2 (en) 2007-02-21 2020-07-21 The Regents Of The University Of Michigan Compositions and methods for tranquilizing heart muscle
EP2137171A4 (en) 2007-03-14 2010-05-19 Knopp Neurosciences Inc SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE
WO2008145252A1 (en) * 2007-05-25 2008-12-04 Boehringer Ingelheim International Gmbh Pharmaceutical formulation comprising pramipexole
WO2008150741A1 (en) * 2007-06-04 2008-12-11 Drugtech Corporation Controlled release dopamine agonist compositions
CA2725482A1 (en) * 2008-06-09 2009-12-17 Supernus Pharmaceuticals, Inc. Controlled release formulations of pramipexole
EP2334185A4 (en) 2008-08-19 2011-09-21 Knopp Neurosciences Inc COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL
WO2010115267A1 (en) * 2009-04-09 2010-10-14 Purdue Pharma Once-daily oral ir/cr pramipexole formulation
EP2448411A4 (en) * 2009-07-02 2012-11-28 Supernus Pharmaceuticals Inc METHOD OF TREATING A NEUROLOGICAL DISORDER
WO2011037976A2 (en) * 2009-09-22 2011-03-31 Dr. Reddy's Laboratories Limited Pramipexole pharmaceutical formulations
WO2011086182A2 (en) * 2010-01-18 2011-07-21 Synthon Bv Pramipexole extended release tablets
TR201001862A1 (tr) * 2010-03-11 2011-10-21 Sanovel �La� San.Ve T�C.A.�. Kontrollü salım gerçekleştiren pramipeksol formülasyonları.
WO2011128914A2 (en) 2010-04-15 2011-10-20 Cadila Healthcare Limited Extended release pharmaceutical compositions of pramipexole
EP2575780A1 (en) 2010-05-24 2013-04-10 Lupin Limited Extended release formulation of pramipexole
CN102670550A (zh) * 2011-03-14 2012-09-19 北京天衡药物研究院 盐酸普拉克索渗透泵型控释片
WO2013034173A1 (en) 2011-09-06 2013-03-14 Synthon Bv Pramipexole extended release tablets
CN102406626B (zh) * 2011-12-02 2013-08-28 深圳海王药业有限公司 盐酸普拉克索缓释片剂及其制备方法
US9512096B2 (en) 2011-12-22 2016-12-06 Knopp Biosciences, LLP Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
EP2732812A1 (de) 2012-11-15 2014-05-21 Aristo Pharma GmbH Pramipexol-Retardtablettenformulierung
CN104744400B (zh) * 2012-11-22 2017-08-11 北京三泉医药技术有限公司 用于治疗神经疾病的四氢苯并噻唑衍生物
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
JP6329717B2 (ja) 2013-07-12 2018-05-23 ノップ バイオサイエンシーズ エルエルシー 高好酸球値および／または高好塩基球値の治療
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
EP3033081B1 (en) 2013-08-13 2021-05-12 Knopp Biosciences LLC Compositions and methods for treating chronic urticaria
WO2015023786A1 (en) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
CN104606162B (zh) * 2015-01-07 2017-03-29 海南康虹医药科技开发有限公司 一种盐酸普拉克索缓释制剂及其制备方法
CN104784155B (zh) * 2015-05-15 2018-02-23 中国药科大学 一种盐酸普拉克索组合微丸胶囊及其制备方法
CN105030721B (zh) * 2015-08-30 2018-05-04 南京康川济医药科技有限公司 一种含有盐酸普拉克索的口服固体组合物
EP3522843B1 (en) * 2016-10-07 2022-09-21 Transwell Biotech Co., Ltd. Pramipexole transdermal delivery system and uses thereof
MX2019007128A (es) * 2016-12-21 2019-09-19 Hso Herbert Schmidt Gmbh & Co Kg Solucion de decapado para decapar materiales sinteticos.
EP3615024A4 (en) * 2017-04-24 2021-01-20 Chase Therapeutics Corporation COMPOSITIONS AND METHODS OF TREATMENT FOR DEPRESSION
CA3072994A1 (en) * 2017-08-17 2019-02-21 Zi-Qiang Gu Pamoate salt of monoamine anti-parkinson's agents, method of preparation and use thereof

Family Cites Families (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2887440A (en) * 1957-08-12 1959-05-19 Dow Chemical Co Enteric coating
US3065143A (en) * 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
NL128902C (da) * 1960-06-06
US3458622A (en) * 1967-04-07 1969-07-29 Squibb & Sons Inc Controlled release tablet
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
JPS58403B2 (ja) * 1975-07-24 1983-01-06 武田薬品工業株式会社 Ｌ− アスコルビンサンセイザイノ セイゾウホウ
US4140755A (en) * 1976-02-13 1979-02-20 Hoffmann-La Roche Inc. Sustained release tablet formulations
US4167558A (en) * 1976-02-13 1979-09-11 Hoffmann-La Roche Inc. Novel sustained release tablet formulations
SE8003805L (sv) 1980-05-21 1981-11-22 Haessle Ab En farmaceutisk beredning med forbettrade utlosningsegenskap
SE8103843L (sv) * 1981-06-18 1982-12-19 Astra Laekemedel Ab Farmaceutisk mixtur
US4424235A (en) * 1981-09-14 1984-01-03 Hoffmann-La Roche Inc. Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
ATE45735T1 (de) * 1984-12-22 1989-09-15 Thomae Gmbh Dr K Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arnzneimittel.
US4738851A (en) * 1985-09-27 1988-04-19 University Of Iowa Research Foundation, Inc. Controlled release ophthalmic gel formulation
US4666612A (en) * 1986-03-17 1987-05-19 Kerr-Mcgee Chemical Corporation Method for recovering a wood preservative from waste sludges
US4772473A (en) * 1986-06-16 1988-09-20 Norwich Eaton Pharmaceuticals, Inc. Nitrofurantoin dosage form
US4709712A (en) * 1986-10-22 1987-12-01 Dermatalogical Products Of Texas Polycarboxylic acid polymer gels as protective agents
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
US4789549A (en) * 1987-03-09 1988-12-06 Warner-Lambert Company Sustained release dosage forms
US4859470A (en) * 1988-06-02 1989-08-22 Alza Corporation Dosage form for delivering diltiazem
GB8828020D0 (en) * 1988-12-01 1989-01-05 Unilever Plc Topical composition
US5026559A (en) * 1989-04-03 1991-06-25 Kinaform Technology, Inc. Sustained-release pharmaceutical preparation
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5273975A (en) * 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
FR2653337B1 (fr) 1989-10-23 1992-02-07 Dow Corning Sa Element a liberation prolongee et procede pour le fabriquer.
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
EP0447168A3 (en) 1990-03-16 1993-01-07 Yamanouchi Pharmaceutical Co. Ltd. Long acting granular pharmaceutical composition
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5656296A (en) * 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
US5731338A (en) * 1992-07-02 1998-03-24 Oramed, Inc. Controlled release pilocarpine delivery system
SK281042B6 (sk) 1992-09-18 2000-11-07 Yamanouchi Pharmaceutical Co., Ltd Prípravok hydrogélového typu s ustáleným uvoľňovaním
DE4241013A1 (de) * 1992-12-05 1994-06-09 Boehringer Ingelheim Kg Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
US5458887A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5484608A (en) 1994-03-28 1996-01-16 Pharmavene, Inc. Sustained-release drug delivery system
DE4432757A1 (de) 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US5650420A (en) 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
WO1997004752A1 (en) 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
SK283370B6 (sk) 1995-12-27 2003-06-03 Janssen Pharmaceutica N. V. Bioadhezívna farmaceutická kompozícia a spôsob jej prípravy
US5846971A (en) * 1996-06-28 1998-12-08 Schering Corporation Oral antifungal composition
JPH1017497A (ja) 1996-07-02 1998-01-20 Takeda Chem Ind Ltd 徐放性製剤およびその製造方法
GB9619074D0 (en) 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
EP0998271B3 (en) * 1997-06-06 2014-10-29 Depomed, Inc. Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
EP1009387B1 (en) 1997-07-02 2006-04-12 Euro-Celtique S.A. Stabilized sustained release tramadol formulations
CA2211778A1 (en) 1997-08-14 1999-02-14 Francois Carriere Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents
US6624200B2 (en) * 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
AU756693B2 (en) 1997-09-29 2003-01-23 Novartis Ag Stabilized bioactive preparations and methods of use
US6197339B1 (en) * 1997-09-30 2001-03-06 Pharmacia & Upjohn Company Sustained release tablet formulation to treat Parkinson's disease
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US20020013304A1 (en) 1997-10-28 2002-01-31 Wilson Leland F. As-needed administration of an androgenic agent to enhance female sexual desire and responsiveness
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
FR2772615B1 (fr) 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
GB9802201D0 (en) 1998-02-03 1998-04-01 Cerestar Holding Bv Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules
CA2323177A1 (en) * 1998-03-11 1999-09-16 Susan Marie Milosovich Composition
JP2002515425A (ja) 1998-05-15 2002-05-28 ファルマシア・アンド・アップジョン・カンパニー カバーゴリンおよびプラミペキソール：新たな使用および組合せ
US6312728B1 (en) 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
TW407058B (en) * 1998-07-17 2000-10-01 Dev Center Biotechnology Oral cisapride dosage forms with an extended duration
US20010055613A1 (en) 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
US6270805B1 (en) 1998-11-06 2001-08-07 Andrx Pharmaceuticals, Inc. Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
ATE313319T1 (de) * 1999-03-31 2006-01-15 Janssen Pharmaceutica Nv Vorgelatinierte stärke in einer formulierung mit gesteuerter freigabe
DE19927688A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
ATE431141T1 (de) * 1999-07-13 2009-05-15 Alpha Res Group Llc Zusammensetzungen und verfahren zur behandlung der parkinson-krankheit
GB9923045D0 (en) 1999-09-29 1999-12-01 Novartis Ag New oral formulations
WO2001022820A1 (en) 1999-09-30 2001-04-05 The General Hospital Corporation Use of pramipexole as a treatment for cocaine craving
CN1409630A (zh) 1999-10-19 2003-04-09 Nps药物有限公司 用于治疗cns－失调疾病之持续释放型制剂
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
AU2731401A (en) * 1999-12-22 2001-07-03 Pharmacia Corporation Sustained-release formulation of a cyclooxygenase-2 inhibitor
CA2332691C (en) * 2000-01-27 2007-11-27 The York Group, Inc. Death care merchandising system
DK2283842T3 (da) 2000-02-08 2015-05-26 Euro Celtique Sa Orale opioid-agonist-formuleringer sikret mod forfalskning
PE20011074A1 (es) * 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
CN1660435A (zh) * 2000-02-24 2005-08-31 法玛西雅厄普约翰美国公司 新的药物联合形式
US6372252B1 (en) 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US6955821B2 (en) * 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
US6277875B1 (en) 2000-07-17 2001-08-21 Andrew J. Holman Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
WO2002011727A1 (en) * 2000-08-08 2002-02-14 Teva Pharmaceutical Industries Ltd. Stable pergolide mesylate and process for making same
ES2187249B1 (es) * 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.
SE0004671D0 (sv) * 2000-12-15 2000-12-15 Amarin Dev Ab Pharmaceutical formulation
ES2398348T3 (es) 2001-07-04 2013-03-15 Sun Pharma Advanced Research Company Ltd Sistema de administración de fármacos controlada por retención gástrica
FR2827872A1 (fr) 2001-07-30 2003-01-31 Roussy Inst Gustave Vesicules membranaires de fluide biologique preleve in vivo, leur preparation et utilisation dans la stimulation d'une reponse immunitaire
US20030032661A1 (en) * 2001-08-02 2003-02-13 Boehringer Ingelheim Pharma Kg Pramipexole as an anticonvulsant
GB0125088D0 (en) 2001-10-18 2001-12-12 Smithkline Beecham Cork Ltd New use
AU2002358270A1 (en) * 2001-12-20 2003-07-09 Pharmacia Corporation Zero-order sustained released dosage forms and method of making the same
CN101410091A (zh) 2002-01-04 2009-04-15 Ivax研究公司 用于持续释放格列吡嗪的药物递送系统
ATE432689T1 (de) 2002-03-04 2009-06-15 Ipsen Pharma Arzneimittelformulierungen mit verzögerter freisetzung mit einem trägerpeptid
ES2627298T3 (es) 2002-04-05 2017-07-27 Mundipharma Pharmaceuticals S.L. Preparación farmacéutica que contiene oxicodona y naloxona
IL164438A0 (en) 2002-04-15 2005-12-18 Adams Lab Inc Sustaubed release of guaifenesin combination drugs
US20030215498A1 (en) * 2002-05-17 2003-11-20 Harland Ronald S. Rapidly disintegrating comressed tablets comprising biologically active compounds
MXPA04012347A (es) 2002-06-10 2005-02-25 Wyeth Corp Nueva sal formiato de o-desmetilvenlafaxina.
AU2003257425A1 (en) 2002-06-27 2004-01-19 Cilag Ag Spherical pellet containing a water-soluble active ingredient
AU2003281181A1 (en) * 2002-07-11 2004-02-02 Takeda Pharmaceutical Company Limited Process for producing coated preparation
AR040680A1 (es) * 2002-07-25 2005-04-13 Pharmacia Corp Composicion de tabletas de liberacion sostenida
CA2488860A1 (en) 2002-07-25 2004-02-05 Pharmacia Corporation Method of preparing solid dosage forms coated in two layers comprising a water-insoluble polymer and a water-soluble pore former
US20050226926A1 (en) * 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
WO2004058228A1 (en) 2002-12-24 2004-07-15 Lupin Limited Enteric coated fluoxetine composition
CA2415154C (en) 2002-12-24 2009-06-16 Biovail Laboratories Inc. Modified release formulations of selective serotonin re-uptake inhibitors
US20050020589A1 (en) * 2003-06-18 2005-01-27 Pfizer Inc. Sustained-release tablet composition comprising a dopamine receptor agonist
CN101843597A (zh) * 2004-08-13 2010-09-29 贝林格尔·英格海姆国际有限公司 包含普拉克索或其可药用盐的延长释放小球制剂、其制备方法及其用途
SI1781260T2 (sl) * 2004-08-13 2014-08-29 Boehringer Ingelheim International Gmbh Tabletna formulacija s podaljšanim sproščanjem, ki vsebuje pramipeksol ali njegovo farmacevtsko sprejemljivo sol, postopek za izdelavo le-te in njena uporaba
WO2007090881A2 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Modified release formulation
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
EP1886665A1 (en) * 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
EA200900270A1 (ru) * 2006-08-25 2009-08-28 Бёрингер Ингельхайм Интернациональ Гмбх Системы регулируемого высвобождения и способ их приготовления

Also Published As

Publication number Publication date
IS7613A (is) 2004-12-23
HRP20041234B1 (hr) 2013-07-31
AP2005003206A0 (en) 2005-03-31
NZ562681A (en) 2009-11-27
RS52764B (en) 2013-10-31
EP2289514A1 (en) 2011-03-02
BR0312948A (pt) 2005-06-14
MXPA05000980A (es) 2005-09-12
CN1671381B (zh) 2010-10-27
UY27913A1 (es) 2004-02-27
ES2421787T9 (es) 2013-11-06
PE20040134A1 (es) 2004-03-06
CA2493629A1 (en) 2004-02-05
DK2289514T5 (da) 2013-09-30
JP2005538995A (ja) 2005-12-22
SI1536792T1 (sl) 2013-11-29
KR20050025654A (ko) 2005-03-14
SI2289514T1 (sl) 2013-08-30
CU23468B7 (es) 2009-12-17
AU2003256921B2 (en) 2009-03-05
ES2421787T3 (es) 2013-09-05
CA2493629C (en) 2013-10-08
CY1114566T1 (el) 2016-10-05
AR040682A1 (es) 2005-04-13
TWI351955B (en) 2011-11-11
HK1078007A1 (en) 2006-03-03
DE20321906U1 (de) 2012-11-07
US20050175691A1 (en) 2005-08-11
IL166076A0 (en) 2006-01-15
PT1536792E (pt) 2013-12-02
AP2223A (en) 2011-03-24
OA12889A (en) 2006-10-13
AU2003256921A1 (en) 2004-02-16
MA27372A1 (fr) 2005-06-01
PA8578501A1 (es) 2005-02-04
KR101066374B1 (ko) 2011-09-20
ECSP055569A (es) 2005-04-18
ZA200500015B (en) 2006-07-26
KR20070062614A (ko) 2007-06-15
JP4607584B2 (ja) 2011-01-05
EP1536792B1 (en) 2013-09-18
EA017595B1 (ru) 2013-01-30
EP2289514B9 (en) 2013-08-21
RS115104A (en) 2006-12-15
WO2004010999A1 (en) 2004-02-05
PT2289514E (pt) 2013-07-23
EA200500080A1 (ru) 2005-06-30
CY1114263T1 (el) 2016-08-31
MY142204A (en) 2010-10-29
PL375444A1 (en) 2005-11-28
TW200418465A (en) 2004-10-01
NO20050481L (no) 2005-01-27
EP2289514B1 (en) 2013-06-19
US20140141079A1 (en) 2014-05-22
DK1536792T3 (da) 2013-11-11
HRP20041234A2 (en) 2005-04-30
ES2436745T3 (es) 2014-01-07
US8679533B2 (en) 2014-03-25
EP1536792A1 (en) 2005-06-08
ME00347B (me) 2011-05-10
MEP52208A (en) 2011-02-10
GEP20074047B (en) 2007-02-26
SG177011A1 (en) 2012-01-30
CN1671381A (zh) 2005-09-21

Similar Documents

Publication Publication Date Title
DK2289514T5 (da) Pramipexol-doseringsform til anvendelse én gang dagligt
DE50309032D1 (de) Fungizide wirkstoffkombinationen
NO20052914D0 (no) Terapeutiske forbindelser
IS7471A (is) Ný efnasambönd
IS7879A (is) Ný efnasambönd
IS7689A (is) Fjölþátta lyfjaskammtaform
DE60317967D1 (de) Umhüllte feste Darreichungsform
ATE434380T1 (de) Fungizide mischungen
NO20055143D0 (no) Doseringsformer innbefattende AG013736
DK3536344T3 (da) Superfin formoterolformulering
DK1565136T3 (da) Sammensætninger for transdermal oxybutynin-terapi
ATE392813T1 (de) Fungizide wirkstoffkombination
DK1862458T3 (da) Terapeutiske midler anvendelige til smertebehandling
IS7827A (is) Ný efnasambönd
IS7381A (is) Efnasambönd
IS7414A (is) Oxó-azabísýklísk efnasambönd
NO20050689L (no) Terapeutisk anvendelse
DE60327447D1 (de) Pflaster
NO20045659L (no) Forbindelser
NO20044188L (no) Kontrollerte frigjoringsdoseformer
NO20022243D0 (no) Fremgangsmåte for rörlegging
FI20020094A (fi) Nefriinintapaisten yhdisteiden käyttö
SE0203751D0 (sv) New Compounds
SE0202908D0 (sv) New compounds
SE0203122D0 (sv) New Compounds