PT99775B - Processo para a preparacao de novos derivados de di-hidroisoquinolina - Google Patents

Processo para a preparacao de novos derivados de di-hidroisoquinolina Download PDF

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Publication number
PT99775B
PT99775B PT99775A PT9977591A PT99775B PT 99775 B PT99775 B PT 99775B PT 99775 A PT99775 A PT 99775A PT 9977591 A PT9977591 A PT 9977591A PT 99775 B PT99775 B PT 99775B
Authority
PT
Portugal
Prior art keywords
compound
formula
ester
compounds
acid addition
Prior art date
Application number
PT99775A
Other languages
English (en)
Portuguese (pt)
Other versions
PT99775A (pt
Inventor
Reto Naef
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of PT99775A publication Critical patent/PT99775A/pt
Publication of PT99775B publication Critical patent/PT99775B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
PT99775A 1990-12-13 1991-12-12 Processo para a preparacao de novos derivados de di-hidroisoquinolina PT99775B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Publications (2)

Publication Number Publication Date
PT99775A PT99775A (pt) 1992-11-30
PT99775B true PT99775B (pt) 1999-05-31

Family

ID=10686945

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99775A PT99775B (pt) 1990-12-13 1991-12-12 Processo para a preparacao de novos derivados de di-hidroisoquinolina

Country Status (25)

Country Link
US (1) US5177085A (enExample)
EP (1) EP0490823B1 (enExample)
JP (1) JPH0764820B2 (enExample)
KR (1) KR920012040A (enExample)
AT (1) ATE145201T1 (enExample)
AU (1) AU643575B2 (enExample)
CA (1) CA2057524A1 (enExample)
CZ (1) CZ281669B6 (enExample)
DE (1) DE69123124T2 (enExample)
DK (1) DK0490823T3 (enExample)
ES (1) ES2093694T3 (enExample)
FI (1) FI915844L (enExample)
GB (1) GB9027055D0 (enExample)
GR (1) GR3022034T3 (enExample)
HU (1) HUT61729A (enExample)
IE (1) IE914325A1 (enExample)
IL (1) IL100328A (enExample)
MX (1) MX9102502A (enExample)
MY (1) MY129941A (enExample)
NZ (1) NZ240936A (enExample)
PL (1) PL168329B1 (enExample)
PT (1) PT99775B (enExample)
RU (1) RU2060992C1 (enExample)
TW (1) TW201736B (enExample)
ZA (1) ZA919858B (enExample)

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US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
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EP0946523A1 (en) 1996-12-23 1999-10-06 Celltech Therapeutics Limited Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors
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GB9705361D0 (en) * 1997-03-14 1997-04-30 Celltech Therapeutics Ltd Chemical compounds
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Also Published As

Publication number Publication date
NZ240936A (en) 1993-09-27
ES2093694T3 (es) 1997-01-01
RU2060992C1 (ru) 1996-05-27
US5177085A (en) 1993-01-05
FI915844A7 (fi) 1992-06-14
IE914325A1 (en) 1992-06-17
TW201736B (enExample) 1993-03-11
KR920012040A (ko) 1992-07-25
PT99775A (pt) 1992-11-30
CA2057524A1 (en) 1992-06-14
MY129941A (en) 2007-05-31
ZA919858B (en) 1993-06-14
MX9102502A (es) 1992-06-01
AU643575B2 (en) 1993-11-18
DK0490823T3 (enExample) 1997-02-17
PL292738A1 (en) 1992-12-14
HU913760D0 (en) 1992-02-28
FI915844A0 (fi) 1991-12-11
EP0490823A1 (en) 1992-06-17
IL100328A (en) 1995-12-08
HUT61729A (en) 1993-03-01
PL168329B1 (pl) 1996-02-29
CS375791A3 (en) 1992-06-17
GB9027055D0 (en) 1991-02-06
AU8898591A (en) 1992-06-18
IL100328A0 (en) 1992-09-06
EP0490823B1 (en) 1996-11-13
JPH0764820B2 (ja) 1995-07-12
DE69123124T2 (de) 1997-05-15
DE69123124D1 (de) 1996-12-19
CZ281669B6 (cs) 1996-12-11
ATE145201T1 (de) 1996-11-15
FI915844L (fi) 1992-06-14
JPH04275276A (ja) 1992-09-30
GR3022034T3 (en) 1997-03-31

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