PT937038E - Analogos de vitamina d - Google Patents
Analogos de vitamina dInfo
- Publication number
- PT937038E PT937038E PT97910261T PT97910261T PT937038E PT 937038 E PT937038 E PT 937038E PT 97910261 T PT97910261 T PT 97910261T PT 97910261 T PT97910261 T PT 97910261T PT 937038 E PT937038 E PT 937038E
- Authority
- PT
- Portugal
- Prior art keywords
- hydrogen
- methylene
- substituted
- optionally
- formula
- Prior art date
Links
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- LVZWSLJZHVFIQJ-UHFFFAOYSA-N Cyclopropane Chemical group C1CC1 LVZWSLJZHVFIQJ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- IYABWNGZIDDRAK-UHFFFAOYSA-N allene Chemical group C=C=C IYABWNGZIDDRAK-UHFFFAOYSA-N 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000000743 hydrocarbylene group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9622590.9A GB9622590D0 (en) | 1996-10-30 | 1996-10-30 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT937038E true PT937038E (pt) | 2002-09-30 |
Family
ID=10802170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97910261T PT937038E (pt) | 1996-10-30 | 1997-10-27 | Analogos de vitamina d |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6310226B1 (pt) |
| EP (1) | EP0937038B1 (pt) |
| JP (1) | JP3907010B2 (pt) |
| KR (1) | KR100526644B1 (pt) |
| CN (1) | CN1107669C (pt) |
| AT (1) | ATE216361T1 (pt) |
| AU (1) | AU722659B2 (pt) |
| CA (1) | CA2266479C (pt) |
| CZ (1) | CZ290933B6 (pt) |
| DE (1) | DE69712086T2 (pt) |
| DK (1) | DK0937038T3 (pt) |
| ES (1) | ES2173425T3 (pt) |
| GB (1) | GB9622590D0 (pt) |
| HU (1) | HUP9904333A3 (pt) |
| NZ (1) | NZ334328A (pt) |
| PL (1) | PL192660B1 (pt) |
| PT (1) | PT937038E (pt) |
| RO (1) | RO120338B1 (pt) |
| RU (1) | RU2183622C2 (pt) |
| WO (1) | WO1998018759A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001510183A (ja) * | 1997-07-17 | 2001-07-31 | エフ．ホフマン−ラ ロシュ アーゲー | 側鎖に２つの不飽和結合を有するジホモ−セコ−コレスタン |
| WO2004046097A1 (en) * | 2002-11-18 | 2004-06-03 | Teva Pharmaceutical Industries Ltd. | A crystallization method for purification of calcipotriene |
| CN1934078B (zh) * | 2004-03-18 | 2011-07-06 | 利奥制药有限公司 | 维生素d类似物的立体选择性合成 |
| WO2006051106A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
| JP5449767B2 (ja) * | 2005-04-25 | 2014-03-19 | サイトクロマ インコーポレイテッド | １α，２５−ジヒドロキシビタミンＤ３の低血漿カルシウム上昇性１６，２３−ジエン−２５−オキシムアナログ |
| AU2007287099A1 (en) | 2006-08-25 | 2008-02-28 | Cougar Biotechnology, Inc. | Methods for treating cancer comprising the administration of a vitamin D compound and an additional therapeutic agent, and compositions containing the same |
| US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
| US20080051375A1 (en) * | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same |
| KR20090039833A (ko) * | 2006-08-29 | 2009-04-22 | 테바 파마슈티컬 인더스트리즈 리미티드 | 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물 |
| CN102341110B (zh) | 2009-01-27 | 2017-04-12 | 博格有限责任公司 | 用于减轻与化疗有关的副作用的维生素d3及其类似物 |
| WO2011002756A2 (en) * | 2009-07-01 | 2011-01-06 | Vitamin Derivatives, Inc. | Vitamin d compounds and methods for preparing same |
| IN2012DN02137A (pt) | 2009-08-14 | 2015-08-07 | Berg Biosystems Llc | |
| AU2014274099A1 (en) | 2013-05-29 | 2015-12-24 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin D |
| JP2019522032A (ja) | 2016-07-29 | 2019-08-08 | ヤンセン ファーマシューティカ エヌ．ベー． | 前立腺癌の治療方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8914963D0 (en) * | 1989-06-29 | 1989-08-23 | Leo Pharm Prod Ltd | Chemical compounds |
| US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
| GB9017890D0 (en) | 1990-08-15 | 1990-09-26 | Leo Pharm Prod Ltd | Chemical compounds i |
| GB9206648D0 (en) * | 1992-03-26 | 1992-05-06 | Leo Pharm Prod Ltd | Chemical compounds |
| GB9223061D0 (en) * | 1992-11-04 | 1992-12-16 | Leo Pharm Prod Ltd | Chemical compounds |
| US5449668A (en) | 1993-06-04 | 1995-09-12 | Duphar International Research B.V. | Vitamin D compounds and method of preparing these compounds |
| US5552392A (en) | 1993-11-03 | 1996-09-03 | Wisconsin Alumni Research Foundation | Method of treating hypoparathyroidism with (20S) vitamin D compounds |
| JP3228488B2 (ja) * | 1993-12-24 | 2001-11-12 | 株式会社クラレ | ２０−エピステロイド誘導体およびその製造方法 |
| JPH0888281A (ja) * | 1994-09-19 | 1996-04-02 | Fujitsu Ltd | 半導体装置 |
| IL118156A (en) * | 1995-05-09 | 2001-08-26 | Duphar Int Res | Vitamin d compounds, their preparation and pharmaceutical compositions containing them |
-
1996
- 1996-10-30 GB GBGB9622590.9A patent/GB9622590D0/en active Pending
-
1997
- 1997-10-27 PT PT97910261T patent/PT937038E/pt unknown
- 1997-10-27 DE DE69712086T patent/DE69712086T2/de not_active Expired - Lifetime
- 1997-10-27 NZ NZ334328A patent/NZ334328A/xx not_active IP Right Cessation
- 1997-10-27 PL PL333068A patent/PL192660B1/pl unknown
- 1997-10-27 KR KR10-1999-7002315A patent/KR100526644B1/ko not_active Expired - Lifetime
- 1997-10-27 RU RU99111777/04A patent/RU2183622C2/ru active
- 1997-10-27 US US09/297,387 patent/US6310226B1/en not_active Expired - Lifetime
- 1997-10-27 RO RO99-00325A patent/RO120338B1/ro unknown
- 1997-10-27 WO PCT/DK1997/000472 patent/WO1998018759A1/en not_active Ceased
- 1997-10-27 EP EP97910261A patent/EP0937038B1/en not_active Expired - Lifetime
- 1997-10-27 ES ES97910261T patent/ES2173425T3/es not_active Expired - Lifetime
- 1997-10-27 CA CA002266479A patent/CA2266479C/en not_active Expired - Lifetime
- 1997-10-27 DK DK97910261T patent/DK0937038T3/da active
- 1997-10-27 JP JP51993198A patent/JP3907010B2/ja not_active Expired - Lifetime
- 1997-10-27 AU AU47717/97A patent/AU722659B2/en not_active Expired
- 1997-10-27 HU HU9904333A patent/HUP9904333A3/hu unknown
- 1997-10-27 CZ CZ19991358A patent/CZ290933B6/cs not_active IP Right Cessation
- 1997-10-27 AT AT97910261T patent/ATE216361T1/de active
- 1997-10-27 CN CN97198407A patent/CN1107669C/zh not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69712086T2 (de) | 2002-11-14 |
| CA2266479C (en) | 2008-09-23 |
| AU4771797A (en) | 1998-05-22 |
| ES2173425T3 (es) | 2002-10-16 |
| DE69712086D1 (de) | 2002-05-23 |
| PL192660B1 (pl) | 2006-11-30 |
| RU2183622C2 (ru) | 2002-06-20 |
| KR20000036233A (ko) | 2000-06-26 |
| PL333068A1 (en) | 1999-11-08 |
| ATE216361T1 (de) | 2002-05-15 |
| EP0937038A1 (en) | 1999-08-25 |
| US6310226B1 (en) | 2001-10-30 |
| HUP9904333A3 (en) | 2001-06-28 |
| CZ135899A3 (cs) | 1999-07-14 |
| JP2001503403A (ja) | 2001-03-13 |
| HUP9904333A2 (hu) | 2000-06-28 |
| RO120338B1 (ro) | 2005-12-30 |
| CZ290933B6 (cs) | 2002-11-13 |
| HK1022298A1 (en) | 2000-08-04 |
| CA2266479A1 (en) | 1998-05-07 |
| CN1232448A (zh) | 1999-10-20 |
| DK0937038T3 (da) | 2002-07-15 |
| NZ334328A (en) | 2000-09-29 |
| JP3907010B2 (ja) | 2007-04-18 |
| KR100526644B1 (ko) | 2005-11-08 |
| AU722659B2 (en) | 2000-08-10 |
| GB9622590D0 (en) | 1997-01-08 |
| WO1998018759A1 (en) | 1998-05-07 |
| EP0937038B1 (en) | 2002-04-17 |
| CN1107669C (zh) | 2003-05-07 |
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