DE69712086D1 - Vitamin d derivate - Google Patents

Vitamin d derivate

Info

Publication number
DE69712086D1
DE69712086D1 DE69712086T DE69712086T DE69712086D1 DE 69712086 D1 DE69712086 D1 DE 69712086D1 DE 69712086 T DE69712086 T DE 69712086T DE 69712086 T DE69712086 T DE 69712086T DE 69712086 D1 DE69712086 D1 DE 69712086D1
Authority
DE
Germany
Prior art keywords
hydrogen
methylene
substituted
optionally
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69712086T
Other languages
English (en)
Other versions
DE69712086T2 (de
Inventor
John Galverley
Henrik Pedersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Application granted granted Critical
Publication of DE69712086D1 publication Critical patent/DE69712086D1/de
Publication of DE69712086T2 publication Critical patent/DE69712086T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE69712086T 1996-10-30 1997-10-27 Vitamin d derivate Expired - Lifetime DE69712086T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9622590.9A GB9622590D0 (en) 1996-10-30 1996-10-30 Chemical compounds
PCT/DK1997/000472 WO1998018759A1 (en) 1996-10-30 1997-10-27 Vitamin d analogues

Publications (2)

Publication Number Publication Date
DE69712086D1 true DE69712086D1 (de) 2002-05-23
DE69712086T2 DE69712086T2 (de) 2002-11-14

Family

ID=10802170

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69712086T Expired - Lifetime DE69712086T2 (de) 1996-10-30 1997-10-27 Vitamin d derivate

Country Status (21)

Country Link
US (1) US6310226B1 (de)
EP (1) EP0937038B1 (de)
JP (1) JP3907010B2 (de)
KR (1) KR100526644B1 (de)
CN (1) CN1107669C (de)
AT (1) ATE216361T1 (de)
AU (1) AU722659B2 (de)
CA (1) CA2266479C (de)
CZ (1) CZ290933B6 (de)
DE (1) DE69712086T2 (de)
DK (1) DK0937038T3 (de)
ES (1) ES2173425T3 (de)
GB (1) GB9622590D0 (de)
HK (1) HK1022298A1 (de)
HU (1) HUP9904333A3 (de)
NZ (1) NZ334328A (de)
PL (1) PL192660B1 (de)
PT (1) PT937038E (de)
RO (1) RO120338B1 (de)
RU (1) RU2183622C2 (de)
WO (1) WO1998018759A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999003828A1 (en) * 1997-07-17 1999-01-28 F.Hoffmann-La Roche Ag Dihomo-seco-cholestanes with two unsaturated bones in the side chain
US7351869B2 (en) * 2002-11-18 2008-04-01 Teva Pharmaceutical Industries Ltd Crystallization method for purification of calcipotriene
BRPI0507318A (pt) * 2004-03-18 2007-06-26 Leo Pharma As métodos para reduzir um composto, para a produção de calcipotriol ou monoidrato de calcipotriol, e de um composto, e de reação da mistura de compostos, composto, e, uso de um composto
US20080293647A1 (en) 2004-11-12 2008-11-27 Luciano Adorini Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
EP1883626B1 (de) * 2005-04-25 2017-10-11 OPKO Ireland Global Holdings, Ltd. Niederkalzemische 16,23-dien-25-oximanaloga von 1alpha,25-dihydroxy-vitamin-d3
WO2008024485A2 (en) 2006-08-25 2008-02-28 Cougar Biotechnology, Inc. Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
JP2010502624A (ja) * 2006-08-29 2010-01-28 テバ ファーマシューティカル インダストリーズ リミティド 低ｐＨ親和性を有するコルチコステロイド化合物及びビタミンＤ含有化合物を含む安定な薬理活性組成物
KR20170096238A (ko) 2009-01-27 2017-08-23 베르그 엘엘씨 화학요법과 연관된 부작용을 경감시키기 위한 비타민 ｄ３ 및 이의 유사물
WO2011002756A2 (en) * 2009-07-01 2011-01-06 Vitamin Derivatives, Inc. Vitamin d compounds and methods for preparing same
JP5978130B2 (ja) 2009-08-14 2016-08-24 バーグ エルエルシー 脱毛症を治療するためのビタミンｄ３およびその類似体
EP3003497B1 (de) 2013-05-29 2024-02-14 BPGbio, Inc. Verhinderung oder verringerung von chemotherapieinduzierter alopezie mit vitamin d

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8914963D0 (en) 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
GB9223061D0 (en) * 1992-11-04 1992-12-16 Leo Pharm Prod Ltd Chemical compounds
US5449668A (en) 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
US5552392A (en) * 1993-11-03 1996-09-03 Wisconsin Alumni Research Foundation Method of treating hypoparathyroidism with (20S) vitamin D compounds
JP3228488B2 (ja) 1993-12-24 2001-11-12 株式会社クラレ ２０−エピステロイド誘導体およびその製造方法
JPH0888281A (ja) * 1994-09-19 1996-04-02 Fujitsu Ltd 半導体装置
CA2175881A1 (en) * 1995-05-09 1996-11-10 Andrzej Kutner Vitamin d compounds and methods of preparing these compounds

Also Published As

Publication number Publication date
DK0937038T3 (da) 2002-07-15
EP0937038B1 (de) 2002-04-17
KR100526644B1 (ko) 2005-11-08
HUP9904333A3 (en) 2001-06-28
CZ135899A3 (cs) 1999-07-14
AU722659B2 (en) 2000-08-10
CA2266479A1 (en) 1998-05-07
WO1998018759A1 (en) 1998-05-07
JP3907010B2 (ja) 2007-04-18
PL333068A1 (en) 1999-11-08
HUP9904333A2 (hu) 2000-06-28
HK1022298A1 (en) 2000-08-04
AU4771797A (en) 1998-05-22
ES2173425T3 (es) 2002-10-16
DE69712086T2 (de) 2002-11-14
RO120338B1 (ro) 2005-12-30
ATE216361T1 (de) 2002-05-15
CN1232448A (zh) 1999-10-20
CN1107669C (zh) 2003-05-07
NZ334328A (en) 2000-09-29
RU2183622C2 (ru) 2002-06-20
CA2266479C (en) 2008-09-23
JP2001503403A (ja) 2001-03-13
KR20000036233A (ko) 2000-06-26
EP0937038A1 (de) 1999-08-25
US6310226B1 (en) 2001-10-30
PL192660B1 (pl) 2006-11-30
GB9622590D0 (en) 1997-01-08
CZ290933B6 (cs) 2002-11-13
PT937038E (pt) 2002-09-30

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: LEO PHARMA A/S ZWEITNAME: LEO PHARMACEUTICAL PRODU

8364 No opposition during term of opposition