PT93502A - Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem

Info

Publication number
PT93502A
PT93502A PT93502A PT9350290A PT93502A PT 93502 A PT93502 A PT 93502A PT 93502 A PT93502 A PT 93502A PT 9350290 A PT9350290 A PT 9350290A PT 93502 A PT93502 A PT 93502A
Authority
PT
Portugal
Prior art keywords
insulin
preparation
pharmaceutical compositions
image
compositions containing
Prior art date
Application number
PT93502A
Other languages
English (en)
Other versions
PT93502B (pt
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT93502A publication Critical patent/PT93502A/pt
Publication of PT93502B publication Critical patent/PT93502B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT93502A 1989-03-20 1990-03-19 Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem PT93502B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (2)

Publication Number Publication Date
PT93502A true PT93502A (pt) 1990-11-07
PT93502B PT93502B (pt) 1996-02-29

Family

ID=8103787

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93502A PT93502B (pt) 1989-03-20 1990-03-19 Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem

Country Status (23)

Country Link
US (1) US5430016A (pt)
EP (1) EP0463072B1 (pt)
JP (1) JPH04503808A (pt)
KR (1) KR920701250A (pt)
CN (1) CN1045793A (pt)
AT (1) ATE116661T1 (pt)
AU (1) AU637365B2 (pt)
CA (1) CA2049961A1 (pt)
DD (1) DD298788A5 (pt)
DE (1) DE69015811T2 (pt)
DK (2) DK134189D0 (pt)
ES (1) ES2068384T3 (pt)
FI (1) FI914419A0 (pt)
GR (1) GR1002545B (pt)
HU (1) HUT58349A (pt)
IE (1) IE66564B1 (pt)
IL (1) IL93792A0 (pt)
NO (1) NO300640B1 (pt)
NZ (1) NZ232953A (pt)
PT (1) PT93502B (pt)
WO (1) WO1990011299A1 (pt)
YU (1) YU53290A (pt)
ZA (1) ZA902086B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
CZ342492A3 (en) * 1991-11-26 1993-06-16 Lilly Co Eli Derivatives of tri-arginine insulin, process of their preparation and a pharmaceutical composition in which said derivatives are comprised
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
ID24890A (id) 1997-10-24 2000-08-31 Lilly Co Eli Komposisi-komposisi insulin yang tidak dapat larut
US6531448B1 (en) * 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
SK2432004A3 (sk) * 2001-12-20 2005-04-01 Eli Lilly And Company Inzulínová zlúčenina s protrahovaným účinkom
US20060217290A1 (en) * 2003-04-29 2006-09-28 Kohn Wayne D Insulin analogs having protracted time action
EP2131723B1 (en) * 2007-03-19 2013-07-24 Insuline Medical Ltd. Device for substance measurement
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
CN104069567A (zh) * 2007-03-19 2014-10-01 茵苏莱恩医药有限公司 药物输送设备
EP2231229A1 (en) 2007-12-18 2010-09-29 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
RU2524423C2 (ru) 2008-01-09 2014-07-27 Санофи-Авентис Дойчланд Гмбх Новые производные инсулина с чрезвычайно замедленным профилем время/действие
CA2711752A1 (en) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
LT2349324T (lt) 2008-10-17 2017-12-27 Sanofi-Aventis Deutschland Gmbh Insulino ir glp-1 agonisto derinys
RU2532893C2 (ru) 2008-11-07 2014-11-10 Инсьюлин Медикал Лтд. Устройство и способ доставки лекарственных средств
CN102711804B (zh) 2009-11-13 2015-09-16 赛诺菲-安万特德国有限公司 包含glp-1激动剂和甲硫氨酸的药物组合物
CA2780460C (en) 2009-11-13 2018-09-04 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a glp-1 agonist, an insulin and methionine
RU2546520C2 (ru) 2010-08-30 2015-04-10 Санофи-Авентис Дойчланд Гмбх Применение ave0010 для производства лекарственного средства для лечения сахарного диабета 2 типа
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
AU2012300978B2 (en) 2011-08-29 2017-04-27 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
TW201534616A (zh) 2013-05-02 2015-09-16 Glaxosmithkline Ip Dev Ltd 治療性胜肽
HUE062573T2 (hu) 2014-12-12 2023-11-28 Sanofi Aventis Deutschland Glargin inzulin/lixiszenatid rögzített arányú készítmény
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
NZ232953A (en) 1992-10-28
FI914419A0 (fi) 1991-09-19
GR1002545B (el) 1997-01-28
EP0463072B1 (en) 1995-01-04
DK0463072T3 (da) 1995-06-12
CN1045793A (zh) 1990-10-03
DD298788A5 (de) 1992-03-12
YU53290A (sh) 1992-12-21
NO300640B1 (no) 1997-06-30
HUT58349A (en) 1992-02-28
AU637365B2 (en) 1993-05-27
ATE116661T1 (de) 1995-01-15
ZA902086B (en) 1990-11-28
DK134189D0 (da) 1989-03-20
WO1990011299A1 (en) 1990-10-04
EP0463072A1 (en) 1992-01-02
NO913687L (no) 1991-11-19
PT93502B (pt) 1996-02-29
ES2068384T3 (es) 1995-04-16
US5430016A (en) 1995-07-04
KR920701250A (ko) 1992-08-11
HU902706D0 (en) 1991-12-30
IE66564B1 (en) 1996-01-24
AU5344890A (en) 1990-10-22
NO913687D0 (no) 1991-09-19
GR900100206A (el) 1991-07-31
IL93792A0 (en) 1990-12-23
CA2049961A1 (en) 1990-09-21
IE901004L (en) 1990-09-20
DE69015811T2 (de) 1995-05-11
DE69015811D1 (de) 1995-02-16
JPH04503808A (ja) 1992-07-09

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19951116

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990531