GR1002545B - Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης. - Google Patents

Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.

Info

Publication number
GR1002545B
GR1002545B GR900100206A GR900100206A GR1002545B GR 1002545 B GR1002545 B GR 1002545B GR 900100206 A GR900100206 A GR 900100206A GR 900100206 A GR900100206 A GR 900100206A GR 1002545 B GR1002545 B GR 1002545B
Authority
GR
Greece
Prior art keywords
preparing new
insulin compositions
new insulin
compositions
preparing
Prior art date
Application number
GR900100206A
Other languages
English (en)
Other versions
GR900100206A (el
Inventor
Benned Finn Hansen
Per Balschmidt
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of GR900100206A publication Critical patent/GR900100206A/el
Publication of GR1002545B publication Critical patent/GR1002545B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR900100206A 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης. GR1002545B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (2)

Publication Number Publication Date
GR900100206A GR900100206A (el) 1991-07-31
GR1002545B true GR1002545B (el) 1997-01-28

Family

ID=8103787

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100206A GR1002545B (el) 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.

Country Status (23)

Country Link
US (1) US5430016A (el)
EP (1) EP0463072B1 (el)
JP (1) JPH04503808A (el)
KR (1) KR920701250A (el)
CN (1) CN1045793A (el)
AT (1) ATE116661T1 (el)
AU (1) AU637365B2 (el)
CA (1) CA2049961A1 (el)
DD (1) DD298788A5 (el)
DE (1) DE69015811T2 (el)
DK (2) DK134189D0 (el)
ES (1) ES2068384T3 (el)
FI (1) FI914419A0 (el)
GR (1) GR1002545B (el)
HU (1) HUT58349A (el)
IE (1) IE66564B1 (el)
IL (1) IL93792A0 (el)
NO (1) NO300640B1 (el)
NZ (1) NZ232953A (el)
PT (1) PT93502B (el)
WO (1) WO1990011299A1 (el)
YU (1) YU53290A (el)
ZA (1) ZA902086B (el)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
NZ245170A (en) * 1991-11-26 1994-07-26 Lilly Co Eli Insulin and proinsulin analogues with arg at b31, b32 and ao and pharmaceutical compositions
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
AU1111799A (en) 1997-10-24 1999-05-17 Eli Lilly And Company Fatty acid-acylated insulin analogs
US6531448B1 (en) 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
BR0215029A (pt) * 2001-12-20 2005-12-20 Lilly Co Eli Molécula de insulina, uso da mesma, composição, uso desta, microcristal, processo para prepará-lo, uso deste, e, métodos para preparar uma molécula de insulina, para tratar hiperglicemia, e para tratar diabetes mellitus
AU2004234345A1 (en) * 2003-04-29 2004-11-11 Eli Lilly And Company Insulin analogs having protracted time action
EP2131723B1 (en) * 2007-03-19 2013-07-24 Insuline Medical Ltd. Device for substance measurement
EP2131900B1 (en) * 2007-03-19 2018-05-30 Insuline Medical Ltd. Drug delivery device
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
JP5695909B2 (ja) 2008-01-09 2015-04-08 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体
BRPI0907371A2 (pt) 2008-01-09 2015-11-24 Sanofi Aventis Deutschland derivados de insulina com um perfil de tempo-ação muito retardado
HUE037449T2 (hu) 2008-10-17 2018-08-28 Sanofi Aventis Deutschland Egy inzulin és egy GLP-1 agonista kombinációja
WO2010052579A2 (en) 2008-11-07 2010-05-14 Insuline Medical Ltd. Device and method for drug delivery
RU2537239C2 (ru) 2009-11-13 2014-12-27 Санофи-Авентис Дойчланд Гмбх Фармацевтическая композиция, включающая агонист glp-1, инсулин и метионин
PE20121316A1 (es) 2009-11-13 2012-10-05 Sanofi Aventis Deutschland Composicion farmaceutica que comprende un agonista de glp-1 y metionina
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (pt) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Acelerómetro pendular
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TW201534616A (zh) 2013-05-02 2015-09-16 Glaxosmithkline Ip Dev Ltd 治療性胜肽
CA2970200A1 (en) 2014-12-12 2016-06-16 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
FI914419A0 (fi) 1991-09-19
WO1990011299A1 (en) 1990-10-04
DE69015811D1 (de) 1995-02-16
NO913687L (no) 1991-11-19
JPH04503808A (ja) 1992-07-09
ZA902086B (en) 1990-11-28
DE69015811T2 (de) 1995-05-11
GR900100206A (el) 1991-07-31
ATE116661T1 (de) 1995-01-15
CA2049961A1 (en) 1990-09-21
IE901004L (en) 1990-09-20
AU637365B2 (en) 1993-05-27
US5430016A (en) 1995-07-04
DK134189D0 (da) 1989-03-20
HU902706D0 (en) 1991-12-30
CN1045793A (zh) 1990-10-03
DD298788A5 (de) 1992-03-12
NZ232953A (en) 1992-10-28
NO913687D0 (no) 1991-09-19
EP0463072A1 (en) 1992-01-02
KR920701250A (ko) 1992-08-11
IE66564B1 (en) 1996-01-24
PT93502B (pt) 1996-02-29
EP0463072B1 (en) 1995-01-04
NO300640B1 (no) 1997-06-30
YU53290A (sh) 1992-12-21
IL93792A0 (en) 1990-12-23
AU5344890A (en) 1990-10-22
PT93502A (pt) 1990-11-07
HUT58349A (en) 1992-02-28
ES2068384T3 (es) 1995-04-16
DK0463072T3 (da) 1995-06-12

Similar Documents

Publication Publication Date Title
GR1002545B (el) Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.
GR3017108T3 (en) Process for preparing peroxidic perfluoropolyethers.
EG19242A (en) Process for preparing oral compositions.
AR243239A1 (es) Procedimiento para preparar polipeptido.
AU7467187A (en) Injectable implant composition having improved intrudability
AU6008890A (en) Bipolar femoral implant
EP0421601A3 (en) Linearizer for qam-receiver
AU3707889A (en) Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same
AU633635B2 (en) Process for preparing bituminous compositions
ZA90474B (en) Vaccine composition
AU7599087A (en) Resinous compositions for denture base
AU632605B2 (en) Material for dentistry
AU7048391A (en) Needle protector
AU7045591A (en) Needle protector
GR900100541A (en) Machine for preparing ice-cubes
IL95980A0 (en) Process for preparing n,n'-bistetrabromophthalimide)
AU2109088A (en) Machine dishwash compositions
EP0490901A4 (en) NEW SPIROFUR DERIVATIVES.
AU6260690A (en) Further novel alkanophenones
AU3665289A (en) Polysilazanes, process for their preparation
AU6740690A (en) Automatic stamp machine
AU4726289A (en) Oxazolidine compound
EP0454494A3 (en) Calicheamicinone, derivatives and analogs thereof and methods of making the same
EP0408332A3 (en) Natural fermentation agent
AU4530689A (en) A process for preparing linear alpha-olefins