DE68922405D1 - Deletionsanaloga von magaininpeptiden. - Google Patents

Deletionsanaloga von magaininpeptiden.

Info

Publication number
DE68922405D1
DE68922405D1 DE68922405T DE68922405T DE68922405D1 DE 68922405 D1 DE68922405 D1 DE 68922405D1 DE 68922405 T DE68922405 T DE 68922405T DE 68922405 T DE68922405 T DE 68922405T DE 68922405 D1 DE68922405 D1 DE 68922405D1
Authority
DE
Germany
Prior art keywords
amino acid
inpeptides
magain
deletion analogs
carboxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68922405T
Other languages
English (en)
Other versions
DE68922405T2 (de
Inventor
Julio CUERVO
Richard Houghten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Application granted granted Critical
Publication of DE68922405D1 publication Critical patent/DE68922405D1/de
Publication of DE68922405T2 publication Critical patent/DE68922405T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE68922405T 1988-12-09 1989-12-05 Deletionsanaloga von magaininpeptiden. Expired - Fee Related DE68922405T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/281,981 US4962277A (en) 1988-12-09 1988-12-09 Deletion analogues of magainin peptides
PCT/US1989/005499 WO1990006129A1 (en) 1988-12-09 1989-12-05 Deletion analogues of magainin peptides

Publications (2)

Publication Number Publication Date
DE68922405D1 true DE68922405D1 (de) 1995-06-01
DE68922405T2 DE68922405T2 (de) 1996-01-04

Family

ID=23079584

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922405T Expired - Fee Related DE68922405T2 (de) 1988-12-09 1989-12-05 Deletionsanaloga von magaininpeptiden.

Country Status (9)

Country Link
US (1) US4962277A (de)
EP (1) EP0451190B1 (de)
JP (1) JP2927539B2 (de)
KR (1) KR0149015B1 (de)
AT (1) ATE121755T1 (de)
CA (1) CA2004991C (de)
DE (1) DE68922405T2 (de)
ES (1) ES2071815T3 (de)
WO (1) WO1990006129A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643876A (en) * 1987-03-04 1997-07-01 The United States Of America As Represented By The Department Of Health And Human Services Biologically active synthetic magainin peptides
SE469132B (sv) * 1989-06-16 1993-05-17 Kabigen Ab Polypeptider och farmaceutisk komposition innehaallande denna
US5912231A (en) * 1989-07-07 1999-06-15 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins
US5585353A (en) * 1990-02-02 1996-12-17 The Rockefeller University Antibiotic peptides containing D-amino acids
US5792831A (en) * 1990-02-08 1998-08-11 Magainin Pharmaceuticals Inc. Analogues of magainin peptides containing D-amino acids
US5459237A (en) * 1990-02-08 1995-10-17 Magainin Pharmaceuticals Inc. Peptide compositions and uses therefor
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
US5208220A (en) * 1990-06-27 1993-05-04 Magainin Pharmaceuticals, Inc. Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase
ATE308562T1 (de) * 1990-08-10 2005-11-15 Virtual Drug Dev Inc Antimikrobielle peptide wirksam gegen pflanzenpathogene, ihre verwendung und auf sie bezogene nachweismethoden
US5235038A (en) * 1991-01-22 1993-08-10 Torry Pines Institute For Molecular Studies Deletion and substitution analogues of melittin peptide
WO1992017195A1 (en) * 1991-04-08 1992-10-15 Magainin Pharmaceuticals, Inc. Novel peptide compositions and uses therefor
US5225399A (en) * 1991-04-15 1993-07-06 The Children's Hospital Of Philadelphia Antimicrobial amphiphilic peptides
US5239059A (en) * 1991-05-10 1993-08-24 The Children's Hospital Of Philadelphia Ion-channel forming peptides
EP0671930A4 (de) * 1991-07-25 1996-02-07 Magainin Pharma Prophylaxe und behandlung der gesundheitlichen schädigung der zahnhygiene durch biologisch aktive peptide.
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
AU5081193A (en) * 1992-08-31 1994-03-29 Magainin Pharmaceuticals, Inc. Treatment of gynecological malignancies with biologically active peptides
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
JPH08507749A (ja) * 1992-12-03 1996-08-20 マガイニン ファーマシューティカルズ，インク． 皮膚悪性疾患の生物学的活性を有するペプチドによる治療
US5847047A (en) * 1993-06-22 1998-12-08 E. I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
PT725629E (pt) * 1993-10-25 2000-11-30 Liposome Co Inc Defensinas em lipossomas
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US5688489A (en) * 1995-09-15 1997-11-18 Resolution Pharmaceuticals, Inc. Non-receptor mediated imaging agents
CN114634553B (zh) * 2022-04-27 2024-03-08 贵州医科大学 阳离子肽c9及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds

Also Published As

Publication number Publication date
EP0451190B1 (de) 1995-04-26
DE68922405T2 (de) 1996-01-04
EP0451190A4 (en) 1992-05-20
US4962277A (en) 1990-10-09
KR0149015B1 (ko) 1998-10-15
KR910700062A (ko) 1991-03-13
CA2004991C (en) 1999-12-07
WO1990006129A1 (en) 1990-06-14
JPH04502159A (ja) 1992-04-16
JP2927539B2 (ja) 1999-07-28
ES2071815T3 (es) 1995-07-01
EP0451190A1 (de) 1991-10-16
CA2004991A1 (en) 1990-06-09
ATE121755T1 (de) 1995-05-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee