KR910700062A - 마가이닌 펩타이드의 결실 동족체 - Google Patents

마가이닌 펩타이드의 결실 동족체

Info

Publication number
KR910700062A
KR910700062A KR1019900701723A KR900701723A KR910700062A KR 910700062 A KR910700062 A KR 910700062A KR 1019900701723 A KR1019900701723 A KR 1019900701723A KR 900701723 A KR900701723 A KR 900701723A KR 910700062 A KR910700062 A KR 910700062A
Authority
KR
South Korea
Prior art keywords
amino acid
marganine
peptides
deletion
carboxy
Prior art date
Application number
KR1019900701723A
Other languages
English (en)
Other versions
KR0149015B1 (ko
Inventor
에이치. 쿠에르보 쥴리오
에이. 호크텐 리챠드
Original Assignee
스크립스 클리닉 앤드 리서치 파운데이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스크립스 클리닉 앤드 리서치 파운데이션 filed Critical 스크립스 클리닉 앤드 리서치 파운데이션
Publication of KR910700062A publication Critical patent/KR910700062A/ko
Application granted granted Critical
Publication of KR0149015B1 publication Critical patent/KR0149015B1/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019900701723A 1988-12-09 1989-12-05 마가이닌 펩타이드의 결실 동족체 KR0149015B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US281,981 1988-12-09
US07/281,981 US4962277A (en) 1988-12-09 1988-12-09 Deletion analogues of magainin peptides
PCT/US1989/005499 WO1990006129A1 (en) 1988-12-09 1989-12-05 Deletion analogues of magainin peptides

Publications (2)

Publication Number Publication Date
KR910700062A true KR910700062A (ko) 1991-03-13
KR0149015B1 KR0149015B1 (ko) 1998-10-15

Family

ID=23079584

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900701723A KR0149015B1 (ko) 1988-12-09 1989-12-05 마가이닌 펩타이드의 결실 동족체

Country Status (9)

Country Link
US (1) US4962277A (ko)
EP (1) EP0451190B1 (ko)
JP (1) JP2927539B2 (ko)
KR (1) KR0149015B1 (ko)
AT (1) ATE121755T1 (ko)
CA (1) CA2004991C (ko)
DE (1) DE68922405T2 (ko)
ES (1) ES2071815T3 (ko)
WO (1) WO1990006129A1 (ko)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643876A (en) * 1987-03-04 1997-07-01 The United States Of America As Represented By The Department Of Health And Human Services Biologically active synthetic magainin peptides
SE469132B (sv) * 1989-06-16 1993-05-17 Kabigen Ab Polypeptider och farmaceutisk komposition innehaallande denna
US5912231A (en) * 1989-07-07 1999-06-15 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins
US5585353A (en) * 1990-02-02 1996-12-17 The Rockefeller University Antibiotic peptides containing D-amino acids
US5459237A (en) * 1990-02-08 1995-10-17 Magainin Pharmaceuticals Inc. Peptide compositions and uses therefor
US5792831A (en) * 1990-02-08 1998-08-11 Magainin Pharmaceuticals Inc. Analogues of magainin peptides containing D-amino acids
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
US5208220A (en) * 1990-06-27 1993-05-04 Magainin Pharmaceuticals, Inc. Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase
JPH07242696A (ja) * 1990-08-10 1995-09-19 Enichem Partecipazioni Spa 植物病原体に対して活性な抗菌性ペプチド、その使用法およびこれに関連するスクリーニング法
US5235038A (en) * 1991-01-22 1993-08-10 Torry Pines Institute For Molecular Studies Deletion and substitution analogues of melittin peptide
EP0579763A4 (en) * 1991-04-08 1994-12-21 Magainin Pharma NOVEL PEPTIDE COMPOSITIONS AND USES.
US5225399A (en) * 1991-04-15 1993-07-06 The Children's Hospital Of Philadelphia Antimicrobial amphiphilic peptides
US5239059A (en) * 1991-05-10 1993-08-24 The Children's Hospital Of Philadelphia Ion-channel forming peptides
JPH07502979A (ja) * 1991-07-25 1995-03-30 マゲイニン ファーマス−ティカルズ,インコーポレーテッド 生物活性ペプチドを利用する口腔内の有害な状態の予防と治療
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
AU5081193A (en) * 1992-08-31 1994-03-29 Magainin Pharmaceuticals, Inc. Treatment of gynecological malignancies with biologically active peptides
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
JPH08507749A (ja) * 1992-12-03 1996-08-20 マガイニン ファーマシューティカルズ,インク. 皮膚悪性疾患の生物学的活性を有するペプチドによる治療
WO1995000547A1 (en) * 1993-06-22 1995-01-05 E.I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
ES2146668T3 (es) * 1993-10-25 2000-08-16 Liposome Co Inc Defensinas liposomicas.
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US5688489A (en) * 1995-09-15 1997-11-18 Resolution Pharmaceuticals, Inc. Non-receptor mediated imaging agents
CN114634553B (zh) * 2022-04-27 2024-03-08 贵州医科大学 阳离子肽c9及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds

Also Published As

Publication number Publication date
DE68922405T2 (de) 1996-01-04
US4962277A (en) 1990-10-09
CA2004991C (en) 1999-12-07
ES2071815T3 (es) 1995-07-01
JPH04502159A (ja) 1992-04-16
EP0451190A4 (en) 1992-05-20
CA2004991A1 (en) 1990-06-09
ATE121755T1 (de) 1995-05-15
WO1990006129A1 (en) 1990-06-14
KR0149015B1 (ko) 1998-10-15
EP0451190B1 (en) 1995-04-26
JP2927539B2 (ja) 1999-07-28
EP0451190A1 (en) 1991-10-16
DE68922405D1 (de) 1995-06-01

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