PT88751A - Processo para a preparacao de proteinas - Google Patents

Processo para a preparacao de proteinas

Info

Publication number
PT88751A
PT88751A PT88751A PT8875188A PT88751A PT 88751 A PT88751 A PT 88751A PT 88751 A PT88751 A PT 88751A PT 8875188 A PT8875188 A PT 8875188A PT 88751 A PT88751 A PT 88751A
Authority
PT
Portugal
Prior art keywords
acid
protein
anhydromevalonolactone
hydroxy
production
Prior art date
Application number
PT88751A
Other languages
English (en)
Other versions
PT88751B (pt
Inventor
Axel Zeeck
Rolf-Gunter Werner
Hans Zahner
Andrea Stecher-Schilling
William Werz
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19873734632 external-priority patent/DE3734632A1/de
Priority claimed from DE19873738649 external-priority patent/DE3738649A1/de
Priority claimed from DE19883801562 external-priority patent/DE3801562A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of PT88751A publication Critical patent/PT88751A/pt
Publication of PT88751B publication Critical patent/PT88751B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6459Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/36Lipids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT88751A 1987-10-13 1988-10-13 Processo para a preparacao de proteinas PT88751B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19873734632 DE3734632A1 (de) 1987-10-13 1987-10-13 Verfahren zur herstellung von t-pa
DE19873738649 DE3738649A1 (de) 1987-11-13 1987-11-13 Verfahren zur herstellung von proteinen
DE19883801562 DE3801562A1 (de) 1988-01-20 1988-01-20 Verfahren zur herstellung von proteinen

Publications (2)

Publication Number Publication Date
PT88751A true PT88751A (pt) 1989-07-31
PT88751B PT88751B (pt) 1995-03-01

Family

ID=27196629

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88751A PT88751B (pt) 1987-10-13 1988-10-13 Processo para a preparacao de proteinas

Country Status (16)

Country Link
EP (1) EP0315782B1 (pt)
JP (1) JP2688222B2 (pt)
KR (1) KR890006671A (pt)
AT (1) ATE112308T1 (pt)
AU (1) AU614999B2 (pt)
CA (1) CA1341400C (pt)
DE (1) DE3851685D1 (pt)
DK (1) DK175411B1 (pt)
ES (1) ES2064336T3 (pt)
FI (1) FI94963C (pt)
HU (1) HU205381B (pt)
IE (1) IE65986B1 (pt)
IL (1) IL88001A (pt)
NO (1) NO174778C (pt)
NZ (1) NZ226521A (pt)
PT (1) PT88751B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2164050T3 (es) * 1991-04-18 2002-02-16 Toray Industries Preparacion de compuestos de interleuquina-6.
DE4113750A1 (de) 1991-04-26 1992-10-29 Boehringer Mannheim Gmbh Verbesserung der renaturierung bei der sekretion von disulfidverbrueckten proteinen
US6309864B1 (en) * 1997-04-03 2001-10-30 Yoshitomi Pharmaceutical Industries, Ltd. Process for producing foreign proteins
JP4249028B2 (ja) * 2001-12-04 2009-04-02 田辺三菱製薬株式会社 蛋白質の活性化方法
CA2511228A1 (en) * 2002-12-20 2004-07-08 Mitsubishi Pharma Corporation Method of protecting thiol group of protein
JP5576115B2 (ja) * 2007-04-26 2014-08-20 中外製薬株式会社 高濃度アミノ酸含有培地を用いた細胞の培養方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163751B1 (en) * 1984-06-05 1989-09-20 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
GB8606386D0 (en) * 1986-03-14 1986-04-23 Celltech Ltd Production of protein

Also Published As

Publication number Publication date
DE3851685D1 (de) 1994-11-03
EP0315782B1 (de) 1994-09-28
HU205381B (en) 1992-04-28
DK175411B1 (da) 2004-09-27
DK567888D0 (da) 1988-10-12
IL88001A0 (en) 1989-06-30
FI884652A0 (fi) 1988-10-11
NO174778B (no) 1994-03-28
IL88001A (en) 1996-01-19
NO884549L (no) 1989-04-14
FI884652A (fi) 1989-04-14
EP0315782A3 (en) 1989-09-20
FI94963B (fi) 1995-08-15
JP2688222B2 (ja) 1997-12-08
DK567888A (da) 1989-04-14
IE883079L (en) 1989-04-13
ATE112308T1 (de) 1994-10-15
IE65986B1 (en) 1995-11-29
KR890006671A (ko) 1989-06-15
NO884549D0 (no) 1988-10-12
AU2373388A (en) 1989-05-11
EP0315782A2 (de) 1989-05-17
HUT48306A (en) 1989-05-29
CA1341400C (en) 2002-11-19
FI94963C (fi) 1995-11-27
ES2064336T3 (es) 1995-02-01
PT88751B (pt) 1995-03-01
JPH01231887A (ja) 1989-09-18
AU614999B2 (en) 1991-09-19
NZ226521A (en) 1991-04-26
NO174778C (no) 1994-07-06

Similar Documents

Publication Publication Date Title
ATE96167T1 (de) Verfahren zur kristallisation von enzymen.
BRPI0412063A (pt) um método para produzir ácido orgánico
SE8500621D0 (sv) Forbettrad proteinframstellning med anvendning av hypertoniska medier
BR0002854B1 (pt) suplementos alimentares para animal contendo lisina aquosa e processo para a sua produÇço
DE69213876T2 (de) Verfahren zum Abtrennen von Lysine in Form von einer wässerigen Lösung und Verwendung dieser Lösung in der Tierernährung
AU7126487A (en) Production of proteins by cell culture
ES2059854T3 (es) Nuevo polipeptido y su produccion.
PT88751A (pt) Processo para a preparacao de proteinas
HUT48307A (en) Process for production of herbicides containing as active substance cyclic internal anhydrid either its free acid form or its salts and process for the production of the activ substances
DE3584218D1 (de) Herstellung von derivaten von a-21978c.
US3930945A (en) Urokinase production
WO1988000968A3 (en) Process for inducing secondary metabolite production in plant cultures and means thereof
ATE91711T1 (de) Verfahren zur enzymatischen hydrolyse von alpha- aminoadipinyl-monoaminoverbindungen.
JPS5318787A (en) Method of cultivating microorganisms
JPS5537136A (en) Preparation of cephalosporin antibiotic
SE8204306D0 (sv) Framstellning av aspartas
ITMI913375A1 (it) Procedimento per la produzione di neuraminidasi
DK0395418T3 (da) Phospholipase A2-inhibitor, fremgangsmåde til fremstilling deraf og farmaceutiske eller veterinære formuleringer omfattende inhibitoren
SU1237709A1 (ru) Способ получени @ -лизина
DK378984D0 (da) Fremgangsmaade til fremstilling af arphamenin i hoejt udbytte
DE69923595D1 (de) Herstellung von proteinen
JPS5668395A (en) Production of d(-)-beta-hydroxyisobutyric acid
ES450400A1 (es) Un procedimiento para preparar un derivado de acido 7-(ace- tamido, sustituido en alfa)-3-metil-3-cefem-4-carboxilico.
ATE77365T1 (de) Verfahren zur herstellung von salzen der dimethylglycylgluconsaeure.
JPS54110384A (en) Culturing medium for humanized lymphocyte

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940831

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20090831