PT88289A - Processo para a preparacao de derivados de quinolona e de naftiridina conyendo um alfa-aminoacido na cadeia lateral do substituinte na posicao 7, com propriedades antibacterianas e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de quinolona e de naftiridina conyendo um alfa-aminoacido na cadeia lateral do substituinte na posicao 7, com propriedades antibacterianas e de composicoes farmaceuticas que os contem

Info

Publication number
PT88289A
PT88289A PT88289A PT8828988A PT88289A PT 88289 A PT88289 A PT 88289A PT 88289 A PT88289 A PT 88289A PT 8828988 A PT8828988 A PT 8828988A PT 88289 A PT88289 A PT 88289A
Authority
PT
Portugal
Prior art keywords
naftiridine
quinolone
substituent
alpha
contain
Prior art date
Application number
PT88289A
Other languages
English (en)
Other versions
PT88289B (pt
Inventor
Joseph Peter Sanchez
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PT88289A publication Critical patent/PT88289A/pt
Publication of PT88289B publication Critical patent/PT88289B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Saccharide Compounds (AREA)
PT88289A 1987-08-21 1988-08-18 Processo para a preparacao de derivados de quinolona e de naftiridina conyendo um alfa-aminoacido na cadeia lateral do substituinte na posicao 7, com propriedades antibacterianas e de composicoes farmaceuticas que os contem PT88289B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8795087A 1987-08-21 1987-08-21
US07/220,177 US4851418A (en) 1987-08-21 1988-07-20 Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent

Publications (2)

Publication Number Publication Date
PT88289A true PT88289A (pt) 1989-09-14
PT88289B PT88289B (pt) 1995-03-31

Family

ID=26777552

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88289A PT88289B (pt) 1987-08-21 1988-08-18 Processo para a preparacao de derivados de quinolona e de naftiridina conyendo um alfa-aminoacido na cadeia lateral do substituinte na posicao 7, com propriedades antibacterianas e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US4851418A (pt)
EP (1) EP0304087B1 (pt)
JP (1) JP2679818B2 (pt)
KR (1) KR0120389B1 (pt)
AU (1) AU608881B2 (pt)
CA (1) CA1339216C (pt)
DE (1) DE3888754T2 (pt)
DK (1) DK172152B1 (pt)
ES (1) ES2063011T3 (pt)
FI (1) FI90237C (pt)
HK (1) HK1000802A1 (pt)
IE (1) IE62787B1 (pt)
NO (1) NO171979C (pt)
NZ (1) NZ225870A (pt)
PH (1) PH25460A (pt)
PT (1) PT88289B (pt)

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FR2676445B1 (fr) * 1991-05-16 1995-02-03 Esteve Labor Dr Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments.
KR100232937B1 (ko) * 1991-05-28 1999-12-01 스즈키 다다시 피리돈카복실산 유도체 및 이를 함유하는 항균제
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
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US5602254A (en) * 1995-05-26 1997-02-11 Warner-Lambert Company Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form
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ATE247089T1 (de) * 1996-11-28 2003-08-15 Wakunaga Pharma Co Ltd Pyridoncarbonsäurederivate oder ihre salze und diese als aktive bestandteile enthaltende medikamente
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US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
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WO2005035493A1 (ja) * 2003-10-08 2005-04-21 Teijin Pharma Limited アミノピロリジン誘導体の製造方法および中間体化合物
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CN101239937B (zh) * 2007-02-07 2010-05-19 上海雅本化学有限公司 一种光学活性r-(-)-1-苄氧羰基-3-氨基吡咯烷及其盐酸盐的制备方法
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Also Published As

Publication number Publication date
NO883722L (no) 1989-02-22
DK467388D0 (da) 1988-08-19
FI90237B (fi) 1993-09-30
JP2679818B2 (ja) 1997-11-19
DE3888754D1 (de) 1994-05-05
NO171979B (no) 1993-02-15
DK172152B1 (da) 1997-12-01
EP0304087A2 (en) 1989-02-22
PT88289B (pt) 1995-03-31
DE3888754T2 (de) 1994-07-14
AU608881B2 (en) 1991-04-18
JPH01125371A (ja) 1989-05-17
NZ225870A (en) 1990-12-21
PH25460A (en) 1991-07-01
IE62787B1 (en) 1995-02-22
NO171979C (no) 1993-05-26
KR890003704A (ko) 1989-04-17
CA1339216C (en) 1997-08-05
AU2062988A (en) 1989-02-23
FI883807A0 (fi) 1988-08-17
FI883807A (fi) 1989-02-22
HK1000802A1 (en) 1998-05-01
EP0304087A3 (en) 1989-10-25
FI90237C (fi) 1994-01-10
US4851418A (en) 1989-07-25
IE882363L (en) 1989-02-21
DK467388A (da) 1989-02-22
KR0120389B1 (ko) 1997-11-04
EP0304087B1 (en) 1994-03-30
NO883722D0 (no) 1988-08-19
ES2063011T3 (es) 1995-01-01

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