NO883722L - Fremgangsmaate for fremstilling av antibakterielle kinolon- og naftyridinderivater. - Google Patents
Fremgangsmaate for fremstilling av antibakterielle kinolon- og naftyridinderivater.Info
- Publication number
- NO883722L NO883722L NO88883722A NO883722A NO883722L NO 883722 L NO883722 L NO 883722L NO 88883722 A NO88883722 A NO 88883722A NO 883722 A NO883722 A NO 883722A NO 883722 L NO883722 L NO 883722L
- Authority
- NO
- Norway
- Prior art keywords
- naphyridine
- quinolon
- antibacterial
- derivatives
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8795087A | 1987-08-21 | 1987-08-21 | |
US07/220,177 US4851418A (en) | 1987-08-21 | 1988-07-20 | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
Publications (4)
Publication Number | Publication Date |
---|---|
NO883722D0 NO883722D0 (no) | 1988-08-19 |
NO883722L true NO883722L (no) | 1989-02-22 |
NO171979B NO171979B (no) | 1993-02-15 |
NO171979C NO171979C (no) | 1993-05-26 |
Family
ID=26777552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO883722A NO171979C (no) | 1987-08-21 | 1988-08-19 | Analogifremgangsmaate for fremstilling av antibakterielle kinolon- og naftyridinderivater |
Country Status (16)
Country | Link |
---|---|
US (1) | US4851418A (no) |
EP (1) | EP0304087B1 (no) |
JP (1) | JP2679818B2 (no) |
KR (1) | KR0120389B1 (no) |
AU (1) | AU608881B2 (no) |
CA (1) | CA1339216C (no) |
DE (1) | DE3888754T2 (no) |
DK (1) | DK172152B1 (no) |
ES (1) | ES2063011T3 (no) |
FI (1) | FI90237C (no) |
HK (1) | HK1000802A1 (no) |
IE (1) | IE62787B1 (no) |
NO (1) | NO171979C (no) |
NZ (1) | NZ225870A (no) |
PH (1) | PH25460A (no) |
PT (1) | PT88289B (no) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3685157D1 (de) * | 1985-06-26 | 1992-06-11 | Daiichi Seiyaku Co | Pyridoncarbonsaeurederivate. |
IN166416B (no) * | 1985-09-18 | 1990-05-05 | Pfizer | |
JPH089597B2 (ja) * | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた8‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
FI88506C (fi) * | 1986-07-04 | 1993-05-25 | Chemie Linz Gmbh | Foerfarande foer framstaellning av farmaceutiskt anvaendbar 7-diazabicykloalkyl-6-fluor-1-(2,4-difluorfenyl)-1,4-dihydro-4-oxo-kinolin-3-karboxylsyra eller karboxylsyraester |
US4780468A (en) * | 1987-08-07 | 1988-10-25 | Warner-Lambert Company | 8-trifluoromethyl quinolones as antibacterial agents |
MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
JPH0395177A (ja) * | 1988-05-19 | 1991-04-19 | Chugai Pharmaceut Co Ltd | 新規キノロンカルボン酸誘導体 |
JP2844079B2 (ja) * | 1988-05-23 | 1999-01-06 | 塩野義製薬株式会社 | ピリドンカルボン酸系抗菌剤 |
FI95130C (fi) * | 1988-07-20 | 1995-12-27 | Sankyo Co | Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi |
US5057520A (en) * | 1989-03-24 | 1991-10-15 | Abbott Laboratories | 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds |
IE76284B1 (en) * | 1988-09-22 | 1997-10-08 | Abbott Lab | Amino acid quinoline and naphthyridine derivatives |
US5057523A (en) * | 1988-09-22 | 1991-10-15 | Abbott Laboratories | Dipeptide quinolone derivatives |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
US5262417A (en) * | 1988-12-06 | 1993-11-16 | The Upjohn Company | Antibacterial quinolone compounds |
US4916141A (en) * | 1989-03-28 | 1990-04-10 | Warner-Lambert Company | (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid |
CA2012681A1 (en) * | 1989-03-31 | 1990-09-30 | Masayasu Okuhira | Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same |
DE3910920A1 (de) * | 1989-04-05 | 1990-10-11 | Bayer Ag | Enantiomerenreine 7-(3-amino-1-pyrrolidinyl)-chinolon- und -naphthyridoncarbonsaeuren |
US5164402A (en) * | 1989-08-16 | 1992-11-17 | Pfizer Inc | Azabicyclo quinolone and naphthyridinone carboxylic acids |
WO1991004972A1 (en) * | 1989-10-06 | 1991-04-18 | Pfizer Inc. | 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents |
US5385913A (en) * | 1989-10-06 | 1995-01-31 | Pfizer Inc. | 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents |
US5084276A (en) * | 1990-01-05 | 1992-01-28 | Abbott Laboratories | Quinolone carboxylic acid compositions with polymeric additive to reduce vein irritation |
ATE193890T1 (de) | 1990-04-18 | 2000-06-15 | Procter & Gamble Pharma | Antimikrobielle chinolonyl-lactame |
AU6367690A (en) * | 1990-07-10 | 1992-05-21 | Hokuriku Pharmaceutical Co. Ltd. | Optically active thiazetoquinoline-3-carboxylic acid compound, method for preparation thereof, and a pharmaceutical composition comprising the same |
US5342846A (en) * | 1990-12-05 | 1994-08-30 | Synphar Laboratories, Inc. | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents |
CA2058640A1 (en) * | 1991-01-25 | 1992-07-26 | Richard R. Scherschlicht | Tricyclic pyridone derivative |
ZA92803B (en) | 1991-02-06 | 1992-11-25 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets |
FR2673426B1 (fr) * | 1991-03-01 | 1993-07-16 | Bouchara Sa | Nouvelles quinolones, leur procede de preparation et les compositions en refermant. |
FR2676445B1 (fr) * | 1991-05-16 | 1995-02-03 | Esteve Labor Dr | Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments. |
AU661999B2 (en) * | 1991-05-28 | 1995-08-17 | Daiichi Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivative |
US5177217A (en) * | 1992-04-27 | 1993-01-05 | Warner-Lambert Company | Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines |
FR2692577B1 (fr) * | 1992-05-26 | 1996-02-02 | Bouchara Sa | Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant. |
US5290794A (en) * | 1992-10-27 | 1994-03-01 | Warner Lambert Co. | Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms |
AU4272793A (en) * | 1993-04-24 | 1994-11-21 | Korea Research Institute Of Chemical Technology | Novel quinolone carboxylic acid derivatives and process for preparing the same |
KR950018003A (ko) * | 1993-12-09 | 1995-07-22 | 스미스클라인 비참 피엘씨 | 신규한 퀴놀론 유도체 및 그의 제조 방법 |
RU2140919C1 (ru) * | 1994-07-18 | 1999-11-10 | Убе Индастриз Лтд. | Производные 8-трифторметилхинолинкарбоновой кислоты, фармацевтическая композиция и способ ингибирования вируса иммунодефицита |
US5602254A (en) * | 1995-05-26 | 1997-02-11 | Warner-Lambert Company | Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form |
ES2178701T3 (es) * | 1995-06-15 | 2003-01-01 | Pfizer | Procedimiento para preparar derivados del acido azabiciclo naftriridina carboxilico que comprenden un dipeptido. |
JP4057088B2 (ja) * | 1996-04-22 | 2008-03-05 | 株式会社カネカ | ピロリジン誘導体の製造方法 |
KR100516379B1 (ko) * | 1996-11-28 | 2005-09-26 | 와쿠나가 세이야쿠 가부시키 가이샤 | 신규 피리돈카르복실산 유도체 또는 그의 염 및 이를 유효 성분으로 하는 의약 |
US6608078B2 (en) | 2000-05-08 | 2003-08-19 | Wockhardt Limited | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment |
US7098219B2 (en) | 2000-08-01 | 2006-08-29 | Wockhart Limited | Inhibitors of cellular efflux pumps of microbes |
SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
US6878713B2 (en) | 2001-04-25 | 2005-04-12 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
US6964966B2 (en) | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
WO2003099815A1 (en) | 2002-05-28 | 2003-12-04 | Wockhardt Limited | Crystalline fluoroquinolone arginine salt form |
ATE366734T1 (de) | 2003-09-04 | 2007-08-15 | Wockhardt Ltd | Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat |
CA2542012A1 (en) * | 2003-10-08 | 2005-04-21 | Teijin Pharma Limited | A method for producing aminopyrrolidine derivatives and intermediate compounds |
KR100939347B1 (ko) | 2005-07-20 | 2010-01-29 | (주)카이로드 | 광학적으로 순수한 (s)-3-히드록시 피롤리딘의 제조방법 |
CN101239937B (zh) * | 2007-02-07 | 2010-05-19 | 上海雅本化学有限公司 | 一种光学活性r-(-)-1-苄氧羰基-3-氨基吡咯烷及其盐酸盐的制备方法 |
AU2008276512A1 (en) * | 2007-07-17 | 2009-01-22 | Amgen Inc. | Thiadiazole modulators of PKB |
US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
CN101983187A (zh) * | 2008-04-02 | 2011-03-02 | 株式会社钟化 | (s)-3-(1-氰基-1,1-二苯基甲基)吡咯烷的制备方法 |
EP2361244B1 (en) | 2008-11-24 | 2013-07-10 | Council of Scientific & Industrial Research | A process for the preparation of optically active n-benzyl-3 hydroxypyrrolidines |
CN114989165A (zh) * | 2022-05-30 | 2022-09-02 | 青岛大学附属医院 | 一种抗持留菌和生物膜菌的化合物或组合物及其用途 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
JPS58174367A (ja) * | 1982-04-07 | 1983-10-13 | Tanabe Seiyaku Co Ltd | キノリン誘導体及びその製法 |
IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
DE3306771A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
JPS60126271A (ja) * | 1983-12-09 | 1985-07-05 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体 |
ZA85853B (en) * | 1984-02-17 | 1986-09-24 | Warner Lambert Co | Antibacterial agents |
JPS60178867A (ja) * | 1984-02-24 | 1985-09-12 | Dai Ichi Seiyaku Co Ltd | ジハロゲノキノリン誘導体 |
US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
JPS60250573A (ja) * | 1984-05-25 | 1985-12-11 | 富士通株式会社 | 電気接続用ソケツト |
JPS61205258A (ja) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体及びその製造方法 |
US4657913A (en) * | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
JPS62469A (ja) * | 1985-06-27 | 1987-01-06 | Dainippon Pharmaceut Co Ltd | 新規キノロン誘導体、そのエステルおよびその塩 |
US4668680A (en) * | 1985-12-12 | 1987-05-26 | Warner-Lambert Company | 5-amino-6,8-difluoroquinolones as antibacterial agents |
-
1988
- 1988-07-20 US US07/220,177 patent/US4851418A/en not_active Expired - Lifetime
- 1988-08-02 CA CA000573632A patent/CA1339216C/en not_active Expired - Fee Related
- 1988-08-02 IE IE236388A patent/IE62787B1/en not_active IP Right Cessation
- 1988-08-08 AU AU20629/88A patent/AU608881B2/en not_active Ceased
- 1988-08-17 FI FI883807A patent/FI90237C/fi not_active IP Right Cessation
- 1988-08-18 NZ NZ225870A patent/NZ225870A/en unknown
- 1988-08-18 PT PT88289A patent/PT88289B/pt not_active IP Right Cessation
- 1988-08-18 PH PH37426A patent/PH25460A/en unknown
- 1988-08-19 EP EP88113525A patent/EP0304087B1/en not_active Expired - Lifetime
- 1988-08-19 DE DE3888754T patent/DE3888754T2/de not_active Expired - Fee Related
- 1988-08-19 JP JP63204893A patent/JP2679818B2/ja not_active Expired - Fee Related
- 1988-08-19 NO NO883722A patent/NO171979C/no not_active IP Right Cessation
- 1988-08-19 ES ES88113525T patent/ES2063011T3/es not_active Expired - Lifetime
- 1988-08-19 DK DK467388A patent/DK172152B1/da not_active IP Right Cessation
- 1988-08-20 KR KR1019880010617A patent/KR0120389B1/ko not_active IP Right Cessation
-
1997
- 1997-12-10 HK HK97102379A patent/HK1000802A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3888754D1 (de) | 1994-05-05 |
DE3888754T2 (de) | 1994-07-14 |
EP0304087B1 (en) | 1994-03-30 |
CA1339216C (en) | 1997-08-05 |
FI883807A (fi) | 1989-02-22 |
IE62787B1 (en) | 1995-02-22 |
KR0120389B1 (ko) | 1997-11-04 |
JP2679818B2 (ja) | 1997-11-19 |
NO171979C (no) | 1993-05-26 |
DK172152B1 (da) | 1997-12-01 |
HK1000802A1 (en) | 1998-05-01 |
KR890003704A (ko) | 1989-04-17 |
US4851418A (en) | 1989-07-25 |
EP0304087A3 (en) | 1989-10-25 |
NO171979B (no) | 1993-02-15 |
PH25460A (en) | 1991-07-01 |
PT88289A (pt) | 1989-09-14 |
AU608881B2 (en) | 1991-04-18 |
JPH01125371A (ja) | 1989-05-17 |
EP0304087A2 (en) | 1989-02-22 |
DK467388D0 (da) | 1988-08-19 |
FI90237C (fi) | 1994-01-10 |
FI90237B (fi) | 1993-09-30 |
AU2062988A (en) | 1989-02-23 |
NO883722D0 (no) | 1988-08-19 |
IE882363L (en) | 1989-02-21 |
PT88289B (pt) | 1995-03-31 |
ES2063011T3 (es) | 1995-01-01 |
FI883807A0 (fi) | 1988-08-17 |
NZ225870A (en) | 1990-12-21 |
DK467388A (da) | 1989-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |