PT87968A - Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem

Info

Publication number
PT87968A
PT87968A PT87968A PT8796888A PT87968A PT 87968 A PT87968 A PT 87968A PT 87968 A PT87968 A PT 87968A PT 8796888 A PT8796888 A PT 8796888A PT 87968 A PT87968 A PT 87968A
Authority
PT
Portugal
Prior art keywords
propanamins
dimetoxy
benzimidazolo
substituted
contain
Prior art date
Application number
PT87968A
Other languages
English (en)
Inventor
Larry Davis
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT87968A publication Critical patent/PT87968A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT87968A 1987-07-13 1988-07-12 Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem PT87968A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/072,954 US4980365A (en) 1987-07-13 1987-07-13 N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents

Publications (1)

Publication Number Publication Date
PT87968A true PT87968A (pt) 1989-06-30

Family

ID=22110785

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87968A PT87968A (pt) 1987-07-13 1988-07-12 Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem

Country Status (5)

Country Link
US (1) US4980365A (pt)
EP (1) EP0299349A2 (pt)
JP (1) JPH0193578A (pt)
DK (1) DK388588A (pt)
PT (1) PT87968A (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030639A (en) * 1987-07-13 1991-07-09 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
ATE119890T1 (de) * 1989-08-04 1995-04-15 Mitsui Toatsu Chemicals Aminoketonderivate und ihre verwendung.
US5338857A (en) * 1989-08-04 1994-08-16 Mitsui Toatsu Chemicals Incorporated Aminoketone derivatives of 1,2-oxazole and use thereof
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
CZ289756B6 (cs) * 1991-03-28 2002-04-17 Eisai Co., Ltd. Heterocyklicko-cyklické aminové deriváty, meziprodukty postupu přípravy těchto sloučenin, farmaceutický prostředek a pouľití uvedených derivátů
WO1994014769A1 (fr) * 1992-12-21 1994-07-07 Taisho Pharmaceutical Co., Ltd. Derive indolique a substitution n
ES2074966B1 (es) * 1994-02-11 1996-06-16 Vita Invest Sa Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
FR2735129B1 (fr) * 1995-06-07 1997-07-11 Adir Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4008033B2 (ja) * 1996-04-19 2007-11-14 ナームローゼ・フエンノートチヤツプ・オルガノン 置換ベンジルアミン及びうつ病の治療のためのその使用
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
KR100542552B1 (ko) 2003-08-21 2006-01-11 삼성전자주식회사 인쇄회로기판, 및 이 인쇄회로기판을 갖는 화상기록장치
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
CN101759693B (zh) * 2008-12-23 2011-09-14 江苏恩华药业股份有限公司 苯骈异恶唑哌啶衍生物及在制备镇痛、镇静药物中的应用
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH556129A (de) * 1973-03-09 1974-11-15 Bbc Brown Boveri & Cie Verfahren zur herstellung einer aus schichten bestehenden elektrischen schaltung.
JPS51136666A (en) * 1975-05-19 1976-11-26 Dainippon Pharmaceut Co Ltd Process for preparing 3-aminoalkyl-1,2-benzisoxazole derivatives.
US4396770A (en) * 1982-04-09 1983-08-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4458075A (en) * 1982-04-09 1984-07-03 Hoechst-Roussel Pharmaceuticals Inc. 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles

Also Published As

Publication number Publication date
JPH0193578A (ja) 1989-04-12
US4980365A (en) 1990-12-25
DK388588D0 (da) 1988-07-12
DK388588A (da) 1989-01-14
EP0299349A2 (en) 1989-01-18

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Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19941114