DK388588A - N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelse - Google Patents
N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelseInfo
- Publication number
- DK388588A DK388588A DK388588A DK388588A DK388588A DK 388588 A DK388588 A DK 388588A DK 388588 A DK388588 A DK 388588A DK 388588 A DK388588 A DK 388588A DK 388588 A DK388588 A DK 388588A
- Authority
- DK
- Denmark
- Prior art keywords
- propanamines
- benzisoxazole
- dimethoxy
- substituted
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/072,954 US4980365A (en) | 1987-07-13 | 1987-07-13 | N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DK388588D0 DK388588D0 (da) | 1988-07-12 |
DK388588A true DK388588A (da) | 1989-01-14 |
Family
ID=22110785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK388588A DK388588A (da) | 1987-07-13 | 1988-07-12 | N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelse |
Country Status (5)
Country | Link |
---|---|
US (1) | US4980365A (da) |
EP (1) | EP0299349A2 (da) |
JP (1) | JPH0193578A (da) |
DK (1) | DK388588A (da) |
PT (1) | PT87968A (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5030639A (en) * | 1987-07-13 | 1991-07-09 | Hoechst-Roussel Pharmaceuticals Inc. | N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents |
US5338857A (en) * | 1989-08-04 | 1994-08-16 | Mitsui Toatsu Chemicals Incorporated | Aminoketone derivatives of 1,2-oxazole and use thereof |
EP0414391B1 (en) * | 1989-08-04 | 1995-03-15 | MITSUI TOATSU CHEMICALS, Inc. | Aminoketone derivatives and use thereof |
ATE231505T1 (de) * | 1991-03-28 | 2003-02-15 | Eisai Co Ltd | Neue heterocyclische/cyclische amine |
US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
CA2152160A1 (en) * | 1992-12-21 | 1994-07-07 | Tomoyuki Ikemoto | N-substituted indole derivative |
ES2074966B1 (es) * | 1994-02-11 | 1996-06-16 | Vita Invest Sa | Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona. |
US6096763A (en) * | 1995-02-23 | 2000-08-01 | Merck & Co., Inc. | α1a adrenergic receptor antagonists |
FR2735129B1 (fr) * | 1995-06-07 | 1997-07-11 | Adir | Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
CN1139580C (zh) * | 1996-04-19 | 2004-02-25 | 阿克佐诺贝尔公司 | 取代的苄胺及它们用于治疗抑郁症的用途 |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
KR100542552B1 (ko) | 2003-08-21 | 2006-01-11 | 삼성전자주식회사 | 인쇄회로기판, 및 이 인쇄회로기판을 갖는 화상기록장치 |
CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료 |
CN101759693B (zh) * | 2008-12-23 | 2011-09-14 | 江苏恩华药业股份有限公司 | 苯骈异恶唑哌啶衍生物及在制备镇痛、镇静药物中的应用 |
PT2398500T (pt) | 2009-02-20 | 2019-06-14 | 2 Bbb Medicines B V | Sistema de entrega de medicamentos à base de glutationas |
TWI556839B (zh) | 2009-05-06 | 2016-11-11 | 研究室護膚股份有限公司 | 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法 |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH556129A (de) * | 1973-03-09 | 1974-11-15 | Bbc Brown Boveri & Cie | Verfahren zur herstellung einer aus schichten bestehenden elektrischen schaltung. |
JPS51136666A (en) * | 1975-05-19 | 1976-11-26 | Dainippon Pharmaceut Co Ltd | Process for preparing 3-aminoalkyl-1,2-benzisoxazole derivatives. |
US4396770A (en) * | 1982-04-09 | 1983-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines |
US4458075A (en) * | 1982-04-09 | 1984-07-03 | Hoechst-Roussel Pharmaceuticals Inc. | 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles |
US4390544A (en) * | 1982-04-09 | 1983-06-28 | Hoechst-Roussel Pharmaceuticals Inc. | {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p |
US4536578A (en) * | 1982-04-09 | 1985-08-20 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines |
US4374245A (en) * | 1982-04-09 | 1983-02-15 | Hoechst-Roussel Pharmaceuticals Inc. | 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
-
1987
- 1987-07-13 US US07/072,954 patent/US4980365A/en not_active Expired - Fee Related
-
1988
- 1988-07-06 EP EP88110775A patent/EP0299349A2/en not_active Withdrawn
- 1988-07-12 JP JP63172009A patent/JPH0193578A/ja active Pending
- 1988-07-12 DK DK388588A patent/DK388588A/da not_active Application Discontinuation
- 1988-07-12 PT PT87968A patent/PT87968A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH0193578A (ja) | 1989-04-12 |
PT87968A (pt) | 1989-06-30 |
US4980365A (en) | 1990-12-25 |
DK388588D0 (da) | 1988-07-12 |
EP0299349A2 (en) | 1989-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |