PT87852B - Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina - Google Patents

Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina Download PDF

Info

Publication number
PT87852B
PT87852B PT87852A PT8785288A PT87852B PT 87852 B PT87852 B PT 87852B PT 87852 A PT87852 A PT 87852A PT 8785288 A PT8785288 A PT 8785288A PT 87852 B PT87852 B PT 87852B
Authority
PT
Portugal
Prior art keywords
formula
carbon atoms
compound
group containing
pyrrolidine
Prior art date
Application number
PT87852A
Other languages
English (en)
Portuguese (pt)
Other versions
PT87852A (pt
Inventor
Emilio Toja
Fernando Barzaghi
Giulio Galliani
Carlo Zirotti
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT87852A publication Critical patent/PT87852A/pt
Publication of PT87852B publication Critical patent/PT87852B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT87852A 1987-06-29 1988-06-28 Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina PT87852B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721098A IT1215590B (it) 1987-06-29 1987-06-29 Derivati della 1-benzene solfonil 2-oco 5-alchiltio pirrolidina, un loro procedimentodi preparazione e il loro impiegocome stostanze medicinali.

Publications (2)

Publication Number Publication Date
PT87852A PT87852A (pt) 1988-07-01
PT87852B true PT87852B (pt) 1992-10-30

Family

ID=11176711

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87852A PT87852B (pt) 1987-06-29 1988-06-28 Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina

Country Status (9)

Country Link
US (1) US4897414A (en, 2012)
EP (1) EP0298818B1 (en, 2012)
JP (1) JPS6426557A (en, 2012)
DE (1) DE3874030T2 (en, 2012)
ES (1) ES2051876T3 (en, 2012)
GR (1) GR3005521T3 (en, 2012)
IT (1) IT1215590B (en, 2012)
MX (1) MX174141B (en, 2012)
PT (1) PT87852B (en, 2012)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1228462B (it) * 1989-02-23 1991-06-19 Roussel Maestretti S P A Milan Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali.
BR9712792A (pt) * 1996-08-28 1999-12-14 Procter & Gamble Inibidores de metaloprotease bidentada.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117975A (en) * 1960-04-22 1964-01-14 Rohm & Haas Substituted pyrrolidinones and piperidinones
US3423426A (en) * 1966-01-25 1969-01-21 Chevron Res N-(polyhaloalkylthio) alkenylsuccinimides
US3686169A (en) * 1970-07-20 1972-08-22 Monsanto Co Thiocycloamides
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf

Also Published As

Publication number Publication date
IT8721098A0 (it) 1987-06-29
ES2051876T3 (es) 1994-07-01
US4897414A (en) 1990-01-30
DE3874030D1 (de) 1992-10-01
DE3874030T2 (de) 1993-03-25
MX174141B (es) 1994-04-25
JPS6426557A (en) 1989-01-27
PT87852A (pt) 1988-07-01
EP0298818B1 (fr) 1992-08-26
MX12051A (es) 1993-10-01
EP0298818A1 (fr) 1989-01-11
GR3005521T3 (en, 2012) 1993-06-07
IT1215590B (it) 1990-02-14

Similar Documents

Publication Publication Date Title
DE69320869T2 (de) Hydroxamsäure Derivate als Collagenase Inhibitore
DE1420072C3 (de) (5'-Dibenzo- eckige Klammer auf a,e eckige Klammer zu -cycloheptatrienyliden)-piperidine, Verfahren zu ihrer Herstellung und Arzneimittel
US3674843A (en) Substituted phenylsulfamyl salicylic acids and derivatives thereof
AU2008207170A1 (en) Use of substituted pyranone acid derivatives for the treatment of metabolic syndrome
BR112020012082A2 (pt) derivados de glicosamina para a prevenção ou tratamento de distúrbios articulares
AU2016304862A1 (en) Compositions and methods for treating and preventing neurodegenerative disorders
EP0229566B1 (fr) Dérivés de la 1-benzène sulfonyl 2-oxo 5-alcoxy pyrrolidine, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant
PT87852B (pt) Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina
DE2705416A1 (de) Neue derivate des m-trifluormethylphenylpiperidins und deren salze, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE2702535C2 (de) N,S-Diacyl-L-cysteine, ihre Herstellung und sie enthaltende Mittel
PT87819B (pt) Processo para a preparacao de novos derivados de 1-benzoil 2-oxo-5-alcoxi pirrolidina
SE440651B (sv) Sett att framstella piperidyl-indol-derivat och farmaceutiska kompositioner innehallande vissa av dessa foreningar
DE2801478A1 (de) N hoch 2 -arylsulfonyl-l-argininamide, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
PT87808B (pt) Processo para a preparacao de novos derivados de 1-arilsulfonil 1,5-dihidro 2h-pirrol 2-ona
PT87656B (pt) Processo para a preparacao de novos derivados de 1-arilsulfonil 2-oxo 5-alcoxi pirrolidina
BRPI0912266B1 (pt) Composto derivado de óxido de benzotiofeno, e, composição farmacêutica
US4810722A (en) 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidines and their use for memory restoration after electoshock treatment
DE3612861A1 (de) 1-hydroxy-8-acyloxy-10-acylanthrone, verfahren zu deren hersellung und diese verbindungen enthaltende kosmetische und pharmazeutische mittel
PT87818B (pt) Processo para a preparacao de novos derivados de 1-benzil 2-oxo-5-alcoxi-pirrolidina
DE2404308C3 (de) Thieno bzw. Furo [3,2-c] pyridiniumderivate sowie deren 43,6,7-Tetrahydroderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
CA1155449A (en) 5-sulfamoyl-orthanilic acids, processes for their preparation and their use as medicaments
AT389310B (de) Cyclohexandion-derivat und verfahren zu seiner herstellung
RU2173146C2 (ru) Производные полициклических алкалоидов как антагонисты nmda-рецептора
SU791228A3 (ru) Способ получени производных аминопропанола или их солей
DE3213082A1 (de) Verbindung mit peripherer gefaesserweiternder wirksamkeit zur verwendung als mittel, das eine roetung der haut bewirkt, verfahren zur herstellung desselben und pharmazeutische kompositionen, die diese verbindung enthalten

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920402

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19951031