DE3874030D1 - 1-benzensulfonyl-2-oxo 5-alkylthio pyrrolidin-derivate, verfahren zur herstellung und zwischenprodukte und verwendung als heilmittel. - Google Patents
1-benzensulfonyl-2-oxo 5-alkylthio pyrrolidin-derivate, verfahren zur herstellung und zwischenprodukte und verwendung als heilmittel.Info
- Publication number
- DE3874030D1 DE3874030D1 DE8888401588T DE3874030T DE3874030D1 DE 3874030 D1 DE3874030 D1 DE 3874030D1 DE 8888401588 T DE8888401588 T DE 8888401588T DE 3874030 T DE3874030 T DE 3874030T DE 3874030 D1 DE3874030 D1 DE 3874030D1
- Authority
- DE
- Germany
- Prior art keywords
- benzensulfonyl
- alkylthio
- oxo
- production
- intermediate products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8721098A IT1215590B (it) | 1987-06-29 | 1987-06-29 | Derivati della 1-benzene solfonil 2-oco 5-alchiltio pirrolidina, un loro procedimentodi preparazione e il loro impiegocome stostanze medicinali. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3874030D1 true DE3874030D1 (de) | 1992-10-01 |
DE3874030T2 DE3874030T2 (de) | 1993-03-25 |
Family
ID=11176711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888401588T Expired - Fee Related DE3874030T2 (de) | 1987-06-29 | 1988-06-23 | 1-benzensulfonyl-2-oxo 5-alkylthio pyrrolidin-derivate, verfahren zur herstellung und zwischenprodukte und verwendung als heilmittel. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4897414A (de) |
EP (1) | EP0298818B1 (de) |
JP (1) | JPS6426557A (de) |
DE (1) | DE3874030T2 (de) |
ES (1) | ES2051876T3 (de) |
GR (1) | GR3005521T3 (de) |
IT (1) | IT1215590B (de) |
MX (1) | MX174141B (de) |
PT (1) | PT87852B (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1228462B (it) * | 1989-02-23 | 1991-06-19 | Roussel Maestretti S P A Milan | Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali. |
BR9712792A (pt) * | 1996-08-28 | 1999-12-14 | Procter & Gamble | Inibidores de metaloprotease bidentada. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3117975A (en) * | 1960-04-22 | 1964-01-14 | Rohm & Haas | Substituted pyrrolidinones and piperidinones |
US3423426A (en) * | 1966-01-25 | 1969-01-21 | Chevron Res | N-(polyhaloalkylthio) alkenylsuccinimides |
US3686169A (en) * | 1970-07-20 | 1972-08-22 | Monsanto Co | Thiocycloamides |
FR2553409B1 (fr) * | 1983-10-18 | 1986-04-18 | Choay Sa | Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques |
CH666891A5 (de) * | 1985-11-26 | 1988-08-31 | Lonza Ag | 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung. |
DK167393B1 (da) * | 1985-12-30 | 1993-10-25 | Roussel Uclaf | 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf |
-
1987
- 1987-06-29 IT IT8721098A patent/IT1215590B/it active
-
1988
- 1988-06-23 ES ES88401588T patent/ES2051876T3/es not_active Expired - Lifetime
- 1988-06-23 EP EP88401588A patent/EP0298818B1/de not_active Expired - Lifetime
- 1988-06-23 DE DE8888401588T patent/DE3874030T2/de not_active Expired - Fee Related
- 1988-06-27 US US07/211,720 patent/US4897414A/en not_active Expired - Fee Related
- 1988-06-27 MX MX012051A patent/MX174141B/es unknown
- 1988-06-28 PT PT87852A patent/PT87852B/pt not_active IP Right Cessation
- 1988-06-28 JP JP63158223A patent/JPS6426557A/ja active Pending
-
1992
- 1992-08-27 GR GR920401011T patent/GR3005521T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
MX12051A (es) | 1993-10-01 |
EP0298818A1 (de) | 1989-01-11 |
IT8721098A0 (it) | 1987-06-29 |
ES2051876T3 (es) | 1994-07-01 |
IT1215590B (it) | 1990-02-14 |
PT87852A (pt) | 1988-07-01 |
EP0298818B1 (de) | 1992-08-26 |
JPS6426557A (en) | 1989-01-27 |
MX174141B (es) | 1994-04-25 |
DE3874030T2 (de) | 1993-03-25 |
US4897414A (en) | 1990-01-30 |
PT87852B (pt) | 1992-10-30 |
GR3005521T3 (de) | 1993-06-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |