PT87852A - Procede de preparation de nouveaux derives de la 1-benzenesulfonyl 2-oxo 5-alkylthio pyrrolidine - Google Patents

Procede de preparation de nouveaux derives de la 1-benzenesulfonyl 2-oxo 5-alkylthio pyrrolidine

Info

Publication number
PT87852A
PT87852A PT87852A PT8785288A PT87852A PT 87852 A PT87852 A PT 87852A PT 87852 A PT87852 A PT 87852A PT 8785288 A PT8785288 A PT 8785288A PT 87852 A PT87852 A PT 87852A
Authority
PT
Portugal
Prior art keywords
benzenesulfonyl
pyrrolidine
alkylthio
oxo
procedure
Prior art date
Application number
PT87852A
Other languages
English (en)
Other versions
PT87852B (pt
Inventor
Emilio Toja
Carlo Zirotti
Fernando Barzaghi
Giulio Galliani
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT87852A publication Critical patent/PT87852A/pt
Publication of PT87852B publication Critical patent/PT87852B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT87852A 1987-06-29 1988-06-28 Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina PT87852B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721098A IT1215590B (it) 1987-06-29 1987-06-29 Derivati della 1-benzene solfonil 2-oco 5-alchiltio pirrolidina, un loro procedimentodi preparazione e il loro impiegocome stostanze medicinali.

Publications (2)

Publication Number Publication Date
PT87852A true PT87852A (pt) 1988-07-01
PT87852B PT87852B (pt) 1992-10-30

Family

ID=11176711

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87852A PT87852B (pt) 1987-06-29 1988-06-28 Processo para a preparacao de novos derivados de 1-benzenosulfonil 2-oxo 5-alquiltio pirrolidina

Country Status (9)

Country Link
US (1) US4897414A (pt)
EP (1) EP0298818B1 (pt)
JP (1) JPS6426557A (pt)
DE (1) DE3874030T2 (pt)
ES (1) ES2051876T3 (pt)
GR (1) GR3005521T3 (pt)
IT (1) IT1215590B (pt)
MX (1) MX174141B (pt)
PT (1) PT87852B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1228462B (it) * 1989-02-23 1991-06-19 Roussel Maestretti S P A Milan Derivati del 1 arilsolfonil pirrolidin 2 tione oppure del 1 arilsolfonil piperidin 2 tione, loro procedimento di preparazione e loro impiego come medicinali.
BR9712792A (pt) * 1996-08-28 1999-12-14 Procter & Gamble Inibidores de metaloprotease bidentada.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117975A (en) * 1960-04-22 1964-01-14 Rohm & Haas Substituted pyrrolidinones and piperidinones
US3423426A (en) * 1966-01-25 1969-01-21 Chevron Res N-(polyhaloalkylthio) alkenylsuccinimides
US3686169A (en) * 1970-07-20 1972-08-22 Monsanto Co Thiocycloamides
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf

Also Published As

Publication number Publication date
MX12051A (es) 1993-10-01
EP0298818A1 (fr) 1989-01-11
IT8721098A0 (it) 1987-06-29
ES2051876T3 (es) 1994-07-01
IT1215590B (it) 1990-02-14
EP0298818B1 (fr) 1992-08-26
JPS6426557A (en) 1989-01-27
DE3874030D1 (de) 1992-10-01
MX174141B (es) 1994-04-25
DE3874030T2 (de) 1993-03-25
US4897414A (en) 1990-01-30
PT87852B (pt) 1992-10-30
GR3005521T3 (pt) 1993-06-07

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920402

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19951031