MC1982A1 - Procede de preparation de derives de la didesoxycitidine - Google Patents

Procede de preparation de derives de la didesoxycitidine

Info

Publication number
MC1982A1
MC1982A1 MC882009A MC2009A MC1982A1 MC 1982 A1 MC1982 A1 MC 1982A1 MC 882009 A MC882009 A MC 882009A MC 2009 A MC2009 A MC 2009A MC 1982 A1 MC1982 A1 MC 1982A1
Authority
MC
Monaco
Prior art keywords
didesoxycitidin
derivatives
preparation
didesoxycitidin derivatives
Prior art date
Application number
MC882009A
Other languages
English (en)
Inventor
Joseph Partridge John
Tam Steve
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1982A1 publication Critical patent/MC1982A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
MC882009A 1987-10-09 1988-10-07 Procede de preparation de derives de la didesoxycitidine MC1982A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10722187A 1987-10-09 1987-10-09

Publications (1)

Publication Number Publication Date
MC1982A1 true MC1982A1 (fr) 1989-11-23

Family

ID=22315505

Family Applications (1)

Application Number Title Priority Date Filing Date
MC882009A MC1982A1 (fr) 1987-10-09 1988-10-07 Procede de preparation de derives de la didesoxycitidine

Country Status (14)

Country Link
EP (1) EP0311100A3 (fr)
JP (1) JPH01132597A (fr)
KR (1) KR890006624A (fr)
AU (1) AU2355488A (fr)
DK (1) DK564088A (fr)
FI (1) FI884627A (fr)
HU (1) HU201090B (fr)
IL (1) IL87949A0 (fr)
MC (1) MC1982A1 (fr)
NO (1) NO884497L (fr)
NZ (1) NZ226481A (fr)
PT (1) PT88716B (fr)
YU (1) YU187788A (fr)
ZA (1) ZA886890B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US6448392B1 (en) 1985-03-06 2002-09-10 Chimerix, Inc. Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use
NZ223910A (en) * 1987-03-20 1991-02-26 Bristol Myers Co 2',3'-dideoxynucleosides, process for their production and intermediates therefor
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
JPH05501404A (ja) * 1989-11-06 1993-03-18 ニユコメド・アクシエセルカペト ヌクレオシド誘導体
US5192764A (en) * 1991-05-30 1993-03-09 Research Foundation Of State Of N.Y. Pyrazinone n-oxide nucleosides and analogs thereof
FI105556B (fi) * 1991-09-30 2000-09-15 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten pyrimidiiniukleosidijohdannaisten valmistamiseksi, joilla on kasvaimen vastaista vaikutusta
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
AU1412299A (en) * 1997-11-25 1999-06-15 Protarga, Inc. Nucleoside analog compositions and uses thereof
WO2002076404A2 (fr) 2001-03-23 2002-10-03 Protarga, Inc. Conjugues d'agents pharmaceutiques et d'alcools gras
JP2005500988A (ja) 2001-03-23 2005-01-13 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪族アミン薬物複合体
KR100978904B1 (ko) * 2001-12-14 2010-08-31 파마셋 인코포레이티드 바이러스 감염 치료용 ｎ4-아실사이토신 뉴클레오사이드
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation
EP3261644B1 (fr) 2015-02-26 2021-06-02 University Of Kentucky Research Foundation Compositions et méthodes pour le traitement de dégradations de la rétine
US11219623B2 (en) 2015-02-26 2022-01-11 University Of Kentucky Research Foundation Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5943550B2 (ja) * 1975-08-29 1984-10-23 田辺製薬株式会社 不飽和ヌクレオシドの製法
AU591125B2 (en) * 1985-05-15 1989-11-30 Wellcome Foundation Limited, The Therapeutic nucleosides
AU613026B2 (en) * 1987-03-24 1991-07-25 Nycomed As 2',3' dideoxyribofuranoxide derivatives
EP0294113A1 (fr) * 1987-05-29 1988-12-07 The Wellcome Foundation Limited Nucléosides thérapeutiques
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds

Also Published As

Publication number Publication date
FI884627A0 (fi) 1988-10-07
ZA886890B (en) 1989-05-30
NO884497D0 (no) 1988-10-07
JPH01132597A (ja) 1989-05-25
EP0311100A3 (fr) 1990-10-31
PT88716B (pt) 1992-12-31
NZ226481A (en) 1992-01-29
DK564088D0 (da) 1988-10-07
HUT47592A (en) 1989-03-28
NO884497L (no) 1989-04-10
IL87949A0 (en) 1989-03-31
FI884627A (fi) 1989-04-10
AU2355488A (en) 1989-04-13
HU201090B (en) 1990-09-28
EP0311100A2 (fr) 1989-04-12
DK564088A (da) 1989-04-10
YU187788A (en) 1990-04-30
KR890006624A (ko) 1989-06-14

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