ZA886890B - Novel dideoxycytidine derivatives - Google Patents

Novel dideoxycytidine derivatives

Info

Publication number
ZA886890B
ZA886890B ZA886890A ZA886890A ZA886890B ZA 886890 B ZA886890 B ZA 886890B ZA 886890 A ZA886890 A ZA 886890A ZA 886890 A ZA886890 A ZA 886890A ZA 886890 B ZA886890 B ZA 886890B
Authority
ZA
South Africa
Prior art keywords
dideoxycytidine
derivatives
novel
novel dideoxycytidine
dideoxycytidine derivatives
Prior art date
Application number
ZA886890A
Other languages
English (en)
Inventor
John Joseph Partridge
Joseph Partridge John
Steve Tam
Tam Steve
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA886890B publication Critical patent/ZA886890B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA886890A 1987-10-09 1988-09-15 Novel dideoxycytidine derivatives ZA886890B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10722187A 1987-10-09 1987-10-09

Publications (1)

Publication Number Publication Date
ZA886890B true ZA886890B (en) 1989-05-30

Family

ID=22315505

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886890A ZA886890B (en) 1987-10-09 1988-09-15 Novel dideoxycytidine derivatives

Country Status (14)

Country Link
EP (1) EP0311100A3 (fr)
JP (1) JPH01132597A (fr)
KR (1) KR890006624A (fr)
AU (1) AU2355488A (fr)
DK (1) DK564088A (fr)
FI (1) FI884627A (fr)
HU (1) HU201090B (fr)
IL (1) IL87949A0 (fr)
MC (1) MC1982A1 (fr)
NO (1) NO884497L (fr)
NZ (1) NZ226481A (fr)
PT (1) PT88716B (fr)
YU (1) YU187788A (fr)
ZA (1) ZA886890B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448392B1 (en) 1985-03-06 2002-09-10 Chimerix, Inc. Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
NZ223910A (en) * 1987-03-20 1991-02-26 Bristol Myers Co 2',3'-dideoxynucleosides, process for their production and intermediates therefor
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
AU636678B2 (en) * 1989-11-06 1993-05-06 Nycomed Imaging As Nucleoside derivatives
US5192764A (en) * 1991-05-30 1993-03-09 Research Foundation Of State Of N.Y. Pyrazinone n-oxide nucleosides and analogs thereof
CA2079413C (fr) * 1991-09-30 2003-09-09 Masakatsu Kaneko Derives de nucleoside pyrimidique ayant une action anti-tumorale, leur preparation et leur utilisation
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
CA2311581A1 (fr) * 1997-11-25 1999-06-03 Protarga, Inc. Compositions d'analogues de nucleosides et utilisation de ces compositions
ATE556706T1 (de) 2001-03-23 2012-05-15 Luitpold Pharm Inc Fettalkohol-arzneimittel-konjugate
JP2005500988A (ja) 2001-03-23 2005-01-13 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪族アミン薬物複合体
WO2003063771A2 (fr) * 2001-12-14 2003-08-07 Pharmasset Ltd. Nucleosides n4-acylcytosines pour le traitement d'infections virales
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation
EP3261644B1 (fr) * 2015-02-26 2021-06-02 University Of Kentucky Research Foundation Compositions et méthodes pour le traitement de dégradations de la rétine
US11219623B2 (en) 2015-02-26 2022-01-11 University Of Kentucky Research Foundation Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5943550B2 (ja) * 1975-08-29 1984-10-23 田辺製薬株式会社 不飽和ヌクレオシドの製法
DE3689976T2 (de) * 1985-05-15 1995-03-16 Wellcome Found Therapeutische Nucleoside und deren Herstellung.
DE3850571T2 (de) * 1987-03-24 1994-10-27 Nycomed Imaging As 2',3'-dideoxyribofuranoxid-derivate.
EP0294113A1 (fr) * 1987-05-29 1988-12-07 The Wellcome Foundation Limited Nucléosides thérapeutiques
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds

Also Published As

Publication number Publication date
AU2355488A (en) 1989-04-13
MC1982A1 (fr) 1989-11-23
FI884627A0 (fi) 1988-10-07
DK564088A (da) 1989-04-10
EP0311100A3 (fr) 1990-10-31
HUT47592A (en) 1989-03-28
KR890006624A (ko) 1989-06-14
PT88716B (pt) 1992-12-31
FI884627A (fi) 1989-04-10
NO884497L (no) 1989-04-10
JPH01132597A (ja) 1989-05-25
DK564088D0 (da) 1988-10-07
NZ226481A (en) 1992-01-29
NO884497D0 (no) 1988-10-07
YU187788A (en) 1990-04-30
HU201090B (en) 1990-09-28
IL87949A0 (en) 1989-03-31
EP0311100A2 (fr) 1989-04-12

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