PT876362E - Novos taxoides sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Novos taxoides sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number
PT876362E
PT876362E PT96942433T PT96942433T PT876362E PT 876362 E PT876362 E PT 876362E PT 96942433 T PT96942433 T PT 96942433T PT 96942433 T PT96942433 T PT 96942433T PT 876362 E PT876362 E PT 876362E
Authority
PT
Portugal
Prior art keywords
contain
preparation
pharmaceutical compositions
new taxoid
taxoid
Prior art date
Application number
PT96942433T
Other languages
English (en)
Portuguese (pt)
Inventor
Alain Commercon
Herve Bouchard
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PT876362E publication Critical patent/PT876362E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT96942433T 1995-12-22 1996-12-19 Novos taxoides sua preparacao e composicoes farmaceuticas que os contem PT876362E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PT876362E true PT876362E (pt) 2004-02-27

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96942433T PT876362E (pt) 1995-12-22 1996-12-19 Novos taxoides sua preparacao e composicoes farmaceuticas que os contem

Country Status (40)

Country Link
US (1) US5728849A (member.php)
EP (1) EP0876362B1 (member.php)
JP (1) JP3953106B2 (member.php)
KR (1) KR100500351B1 (member.php)
CN (1) CN1103766C (member.php)
AR (1) AR005197A1 (member.php)
AT (1) ATE250593T1 (member.php)
AU (1) AU712597B2 (member.php)
BG (1) BG63204B1 (member.php)
BR (1) BR9612135A (member.php)
CA (1) CA2238884C (member.php)
CO (1) CO4520184A1 (member.php)
CZ (1) CZ294972B6 (member.php)
DE (1) DE69630145T2 (member.php)
DK (1) DK0876362T3 (member.php)
DZ (1) DZ2149A1 (member.php)
EA (1) EA001533B1 (member.php)
ES (1) ES2202490T3 (member.php)
FR (1) FR2742751B1 (member.php)
HU (1) HU225032B1 (member.php)
IL (1) IL124994A (member.php)
IN (4) IN186768B (member.php)
MA (1) MA26412A1 (member.php)
MX (1) MX9804688A (member.php)
MY (1) MY113934A (member.php)
NO (1) NO317358B1 (member.php)
NZ (1) NZ324337A (member.php)
OA (1) OA10700A (member.php)
PE (1) PE25198A1 (member.php)
PL (1) PL189311B1 (member.php)
PT (1) PT876362E (member.php)
RO (1) RO116194B1 (member.php)
SK (1) SK282835B6 (member.php)
TN (1) TNSN96169A1 (member.php)
TR (1) TR199801179T2 (member.php)
TW (1) TW371659B (member.php)
UA (1) UA48205C2 (member.php)
UY (1) UY24386A1 (member.php)
WO (1) WO1997023473A1 (member.php)
ZA (1) ZA9610737B (member.php)

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US6660866B2 (en) 2000-02-02 2003-12-09 Psu Research Foundation, Inc. C10 carbonate substituted taxanes
HRPK20110926B3 (hr) * 2001-02-24 2013-05-31 Boehringer Ingelheim Pharma Gmbh & Co.Kg. Derivati ksantina, njihova proizvodnja i upotreba kao lijekova
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
CA2526278A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
MX2008014024A (es) * 2006-05-04 2008-11-14 Boehringer Ingelheim Int Formas poliformas.
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
EP2190434B1 (en) * 2007-08-17 2019-04-17 Boehringer Ingelheim International GmbH Purin derivatives for use in the treatment of fap-related diseases
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
KR101657960B1 (ko) * 2008-08-15 2016-09-20 베링거 인겔하임 인터내셔날 게엠베하 Ｆａｂ-관련 질환의 치료에 사용하기 위한 푸린 유도체
AU2009290911A1 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
MX2011006713A (es) 2008-12-23 2011-07-13 Boehringer Ingelheim Int Formas salinas de compuesto organico.
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
EP2504002B1 (en) 2009-11-27 2019-10-09 Boehringer Ingelheim International GmbH Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
PH12012502162A1 (en) 2010-05-05 2013-02-04 Boehringer Ingelheim Int Combination therapy
KR102018038B1 (ko) 2010-06-24 2019-09-05 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
PL2731947T3 (pl) 2011-07-15 2019-07-31 Boehringer Ingelheim International Gmbh Podstawiona dimeryczna pochodna chinazoliny, sposób jej wytwarzania i jej zastosowanie w kompozycjach farmaceutycznych do leczenia cukrzycy typu I i II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171166A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
JP6224084B2 (ja) 2012-05-14 2017-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
CN105849086B (zh) 2012-11-24 2018-07-31 杭州多禧生物科技有限公司 亲水性链接体及其在药物分子和细胞结合分子共轭反应上的应用
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
CN114262344A (zh) 2014-02-28 2022-04-01 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
US9526728B2 (en) 2014-02-28 2016-12-27 Boehringer Ingelheim International Gmbh Medical use of a DPP-4 inhibitor
EP3319936B1 (en) 2015-07-12 2025-12-17 Hangzhou Dac Biotech Co., Ltd. Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
BR112018072401A2 (pt) 2016-06-10 2019-02-19 Boehringer Ingelheim International Gmbh combinações de linagliptina e metformina
US12364767B2 (en) 2016-11-14 2025-07-22 Hangzhou Dac Biotech Co., Ltd. Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers
KR20240095442A (ko) 2021-11-03 2024-06-25 항저우 디에이씨 바이오테크 씨오, 엘티디 항체의 특이적 접합

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
EP0639186B1 (en) * 1992-04-17 1999-06-23 Abbott Laboratories Taxol derivatives
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
DK0876362T3 (da) 2004-02-02
IL124994A (en) 2000-12-06
ATE250593T1 (de) 2003-10-15
CO4520184A1 (es) 1997-10-15
EA001533B1 (ru) 2001-04-23
IL124994A0 (en) 1999-01-26
KR19990076680A (ko) 1999-10-15
IN188470B (member.php) 2002-09-28
CZ294972B6 (cs) 2005-04-13
AU1180997A (en) 1997-07-17
MA26412A1 (fr) 2004-12-20
FR2742751A1 (fr) 1997-06-27
PL327405A1 (en) 1998-12-07
BG63204B1 (bg) 2001-06-29
KR100500351B1 (ko) 2005-12-21
AR005197A1 (es) 1999-04-14
RO116194B1 (ro) 2000-11-30
DZ2149A1 (fr) 2002-10-23
CA2238884C (fr) 2007-02-06
EA199800588A1 (ru) 1998-12-24
JP2000502671A (ja) 2000-03-07
HUP9904046A1 (hu) 2001-04-28
JP3953106B2 (ja) 2007-08-08
UY24386A1 (es) 2001-08-27
SK282835B6 (sk) 2002-12-03
IN188680B (member.php) 2002-10-26
EP0876362B1 (fr) 2003-09-24
MY113934A (en) 2002-06-29
FR2742751B1 (fr) 1998-01-30
EP0876362A1 (fr) 1998-11-11
HU225032B1 (en) 2006-05-29
NZ324337A (en) 2000-03-27
TNSN96169A1 (fr) 2005-03-15
NO317358B1 (no) 2004-10-18
IN186768B (member.php) 2001-11-03
DE69630145D1 (de) 2003-10-30
DE69630145T2 (de) 2004-07-15
PL189311B1 (pl) 2005-07-29
CN1103766C (zh) 2003-03-26
NO982580L (no) 1998-06-05
MX9804688A (es) 1998-10-31
PE25198A1 (es) 1998-05-10
HK1017895A1 (en) 1999-12-03
ES2202490T3 (es) 2004-04-01
BG102569A (en) 1999-04-30
ZA9610737B (en) 1997-06-27
IN188469B (member.php) 2002-09-28
HUP9904046A3 (en) 2001-08-28
CA2238884A1 (fr) 1997-07-03
OA10700A (fr) 2002-11-27
TR199801179T2 (xx) 1998-10-21
BR9612135A (pt) 1999-07-13
CN1205697A (zh) 1999-01-20
TW371659B (en) 1999-10-11
NO982580D0 (no) 1998-06-05
US5728849A (en) 1998-03-17
UA48205C2 (uk) 2002-08-15
WO1997023473A1 (fr) 1997-07-03
SK85398A3 (en) 1998-11-04
AU712597B2 (en) 1999-11-11
CZ196198A3 (cs) 1998-09-16

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