PT876362E - Novos taxoides sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Novos taxoides sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number
PT876362E
PT876362E PT96942433T PT96942433T PT876362E PT 876362 E PT876362 E PT 876362E PT 96942433 T PT96942433 T PT 96942433T PT 96942433 T PT96942433 T PT 96942433T PT 876362 E PT876362 E PT 876362E
Authority
PT
Portugal
Prior art keywords
contain
preparation
pharmaceutical compositions
new taxoid
taxoid
Prior art date
Application number
PT96942433T
Other languages
English (en)
Portuguese (pt)
Inventor
Alain Commercon
Herve Bouchard
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PT876362E publication Critical patent/PT876362E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT96942433T 1995-12-22 1996-12-19 Novos taxoides sua preparacao e composicoes farmaceuticas que os contem PT876362E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PT876362E true PT876362E (pt) 2004-02-27

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96942433T PT876362E (pt) 1995-12-22 1996-12-19 Novos taxoides sua preparacao e composicoes farmaceuticas que os contem

Country Status (40)

Country Link
US (1) US5728849A (cg-RX-API-DMAC7.html)
EP (1) EP0876362B1 (cg-RX-API-DMAC7.html)
JP (1) JP3953106B2 (cg-RX-API-DMAC7.html)
KR (1) KR100500351B1 (cg-RX-API-DMAC7.html)
CN (1) CN1103766C (cg-RX-API-DMAC7.html)
AR (1) AR005197A1 (cg-RX-API-DMAC7.html)
AT (1) ATE250593T1 (cg-RX-API-DMAC7.html)
AU (1) AU712597B2 (cg-RX-API-DMAC7.html)
BG (1) BG63204B1 (cg-RX-API-DMAC7.html)
BR (1) BR9612135A (cg-RX-API-DMAC7.html)
CA (1) CA2238884C (cg-RX-API-DMAC7.html)
CO (1) CO4520184A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ294972B6 (cg-RX-API-DMAC7.html)
DE (1) DE69630145T2 (cg-RX-API-DMAC7.html)
DK (1) DK0876362T3 (cg-RX-API-DMAC7.html)
DZ (1) DZ2149A1 (cg-RX-API-DMAC7.html)
EA (1) EA001533B1 (cg-RX-API-DMAC7.html)
ES (1) ES2202490T3 (cg-RX-API-DMAC7.html)
FR (1) FR2742751B1 (cg-RX-API-DMAC7.html)
HU (1) HU225032B1 (cg-RX-API-DMAC7.html)
IL (1) IL124994A (cg-RX-API-DMAC7.html)
IN (4) IN186768B (cg-RX-API-DMAC7.html)
MA (1) MA26412A1 (cg-RX-API-DMAC7.html)
MX (1) MX9804688A (cg-RX-API-DMAC7.html)
MY (1) MY113934A (cg-RX-API-DMAC7.html)
NO (1) NO317358B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ324337A (cg-RX-API-DMAC7.html)
OA (1) OA10700A (cg-RX-API-DMAC7.html)
PE (1) PE25198A1 (cg-RX-API-DMAC7.html)
PL (1) PL189311B1 (cg-RX-API-DMAC7.html)
PT (1) PT876362E (cg-RX-API-DMAC7.html)
RO (1) RO116194B1 (cg-RX-API-DMAC7.html)
SK (1) SK282835B6 (cg-RX-API-DMAC7.html)
TN (1) TNSN96169A1 (cg-RX-API-DMAC7.html)
TR (1) TR199801179T2 (cg-RX-API-DMAC7.html)
TW (1) TW371659B (cg-RX-API-DMAC7.html)
UA (1) UA48205C2 (cg-RX-API-DMAC7.html)
UY (1) UY24386A1 (cg-RX-API-DMAC7.html)
WO (1) WO1997023473A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA9610737B (cg-RX-API-DMAC7.html)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
CZ20013405A3 (cs) 2000-02-02 2002-03-13 Florida State University Research Foundation, Inc. C10 karbonátem substituované taxany jako protinádorová činidla
DK1757606T3 (da) * 2001-02-24 2009-09-07 Boehringer Ingelheim Pharma Anvendelse af xanthinderivater som l gemidler samt fremgangsm de til deres fremstilling
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
CA2526278A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
JP5323684B2 (ja) * 2006-05-04 2013-10-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 多形体
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
AU2008290582B2 (en) * 2007-08-17 2014-08-14 Boehringer Ingelheim International Gmbh Purin derivatives for use in the treatment of fab-related diseases
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
EP2326326B1 (en) * 2008-08-15 2019-10-09 Boehringer Ingelheim International GmbH Dpp-4 inhibitors for use for the treatment of wound healing in diabetic patients
JP2012502081A (ja) 2008-09-10 2012-01-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糖尿病及び関連症状の治療のための組み合わせ治療
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
TWI508965B (zh) 2008-12-23 2015-11-21 Boehringer Ingelheim Int 有機化合物的鹽形式
TW201036975A (en) 2009-01-07 2010-10-16 Boehringer Ingelheim Int Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
KR20190071840A (ko) 2009-11-27 2019-06-24 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
MX366325B (es) 2010-05-05 2019-07-05 Boehringer Ingelheim Int Terapia de combinacion.
CA2803504C (en) 2010-06-24 2022-08-30 Boehringer Ingelheim International Gmbh A combination for diabetes therapy comprising linagliptin and a long-acting insulin
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
KR101985384B1 (ko) 2011-07-15 2019-06-03 베링거 인겔하임 인터내셔날 게엠베하 치환된 퀴나졸린, 이의 제조 및 약제학적 조성물에서의 이의 용도
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
JP6218811B2 (ja) 2012-05-14 2017-10-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｓｉｒｓ及び／又は敗血症の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
EP2849755A1 (en) 2012-05-14 2015-03-25 Boehringer Ingelheim International GmbH A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
AU2012395148B2 (en) 2012-11-24 2016-10-27 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
PT3122757T (pt) 2014-02-28 2023-11-03 Hangzhou Dac Biotech Co Ltd Ligantes carregados e as suas utilizações em conjugação
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
WO2015151081A2 (en) 2015-07-12 2015-10-08 Suzhou M-Conj Biotech Co., Ltd Bridge linkers for conjugation of a cell-binding molecule
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
BR112018072401A2 (pt) 2016-06-10 2019-02-19 Boehringer Ingelheim International Gmbh combinações de linagliptina e metformina
WO2018086139A1 (en) 2016-11-14 2018-05-17 Hangzhou Dac Biotech Co., Ltd Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers
JP2024541058A (ja) 2021-11-03 2024-11-06 ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． 抗体の特異的共役

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
ES2134847T3 (es) * 1992-04-17 1999-10-16 Abbott Lab Derivados de taxol.
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
AU1180997A (en) 1997-07-17
EP0876362A1 (fr) 1998-11-11
IN188469B (cg-RX-API-DMAC7.html) 2002-09-28
IN186768B (cg-RX-API-DMAC7.html) 2001-11-03
NZ324337A (en) 2000-03-27
UY24386A1 (es) 2001-08-27
DE69630145D1 (de) 2003-10-30
OA10700A (fr) 2002-11-27
PL189311B1 (pl) 2005-07-29
CO4520184A1 (es) 1997-10-15
IL124994A0 (en) 1999-01-26
HUP9904046A1 (hu) 2001-04-28
CZ294972B6 (cs) 2005-04-13
TW371659B (en) 1999-10-11
EA199800588A1 (ru) 1998-12-24
TR199801179T2 (xx) 1998-10-21
HUP9904046A3 (en) 2001-08-28
AU712597B2 (en) 1999-11-11
CA2238884A1 (fr) 1997-07-03
IL124994A (en) 2000-12-06
NO982580L (no) 1998-06-05
IN188470B (cg-RX-API-DMAC7.html) 2002-09-28
JP3953106B2 (ja) 2007-08-08
SK282835B6 (sk) 2002-12-03
BR9612135A (pt) 1999-07-13
DZ2149A1 (fr) 2002-10-23
EA001533B1 (ru) 2001-04-23
US5728849A (en) 1998-03-17
KR100500351B1 (ko) 2005-12-21
ZA9610737B (en) 1997-06-27
MX9804688A (es) 1998-10-31
ATE250593T1 (de) 2003-10-15
UA48205C2 (uk) 2002-08-15
CZ196198A3 (cs) 1998-09-16
PL327405A1 (en) 1998-12-07
IN188680B (cg-RX-API-DMAC7.html) 2002-10-26
BG63204B1 (bg) 2001-06-29
AR005197A1 (es) 1999-04-14
KR19990076680A (ko) 1999-10-15
DE69630145T2 (de) 2004-07-15
RO116194B1 (ro) 2000-11-30
FR2742751B1 (fr) 1998-01-30
CA2238884C (fr) 2007-02-06
CN1205697A (zh) 1999-01-20
ES2202490T3 (es) 2004-04-01
NO317358B1 (no) 2004-10-18
HK1017895A1 (en) 1999-12-03
EP0876362B1 (fr) 2003-09-24
MA26412A1 (fr) 2004-12-20
DK0876362T3 (da) 2004-02-02
TNSN96169A1 (fr) 2005-03-15
PE25198A1 (es) 1998-05-10
MY113934A (en) 2002-06-29
FR2742751A1 (fr) 1997-06-27
BG102569A (en) 1999-04-30
HU225032B1 (en) 2006-05-29
SK85398A3 (en) 1998-11-04
WO1997023473A1 (fr) 1997-07-03
CN1103766C (zh) 2003-03-26
JP2000502671A (ja) 2000-03-07
NO982580D0 (no) 1998-06-05

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