MXPA01009902A - Taxanos sustituidos con carbonato en c10 como agentes antitumor. - Google Patents
Taxanos sustituidos con carbonato en c10 como agentes antitumor.Info
- Publication number
- MXPA01009902A MXPA01009902A MXPA01009902A MXPA01009902A MXPA01009902A MX PA01009902 A MXPA01009902 A MX PA01009902A MX PA01009902 A MXPA01009902 A MX PA01009902A MX PA01009902 A MXPA01009902 A MX PA01009902A MX PA01009902 A MXPA01009902 A MX PA01009902A
- Authority
- MX
- Mexico
- Prior art keywords
- antitumor agents
- carbonate substituted
- substituted taxanes
- taxanes
- carbonate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17968400P | 2000-02-02 | 2000-02-02 | |
| PCT/US2001/003588 WO2001057031A1 (en) | 2000-02-02 | 2001-02-02 | C10 carbonate substituted taxanes as antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA01009902A true MXPA01009902A (es) | 2003-07-28 |
Family
ID=22657547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA01009902A MXPA01009902A (es) | 2000-02-02 | 2001-02-02 | Taxanos sustituidos con carbonato en c10 como agentes antitumor. |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US6660866B2 (es) |
| EP (1) | EP1165550A1 (es) |
| JP (1) | JP2003522171A (es) |
| KR (1) | KR20010111582A (es) |
| CN (1) | CN1186340C (es) |
| AU (1) | AU782028B2 (es) |
| BG (1) | BG65298B1 (es) |
| BR (1) | BR0104779A (es) |
| CA (1) | CA2368151A1 (es) |
| CZ (1) | CZ20013405A3 (es) |
| GE (1) | GEP20043239B (es) |
| HK (1) | HK1053472A1 (es) |
| HU (1) | HUP0200759A3 (es) |
| IL (1) | IL145636A0 (es) |
| MX (1) | MXPA01009902A (es) |
| NO (1) | NO20014753L (es) |
| NZ (1) | NZ514074A (es) |
| PL (1) | PL350028A1 (es) |
| RO (1) | RO121269B1 (es) |
| RU (1) | RU2264400C2 (es) |
| SK (1) | SK13632001A3 (es) |
| TR (1) | TR200102855T1 (es) |
| UA (1) | UA75038C2 (es) |
| WO (1) | WO2001057031A1 (es) |
| ZA (2) | ZA200108054B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003522171A (ja) | 2000-02-02 | 2003-07-22 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | 抗腫瘍剤としてのｃ１０カーボネート置換タキサン |
| US6649632B2 (en) * | 2000-02-02 | 2003-11-18 | Fsu Research Foundation, Inc. | C10 ester substituted taxanes |
| RU2265019C2 (ru) * | 2000-02-02 | 2005-11-27 | Флорида Стейт Юниверсити Рисерч Фаундейшн, Инк. | Таксаны, фармацевтические композиции, способы ингибирования |
| JP2003521545A (ja) * | 2000-02-02 | 2003-07-15 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | 改良された溶解性を有するタキサン製剤 |
| CA2354478A1 (en) * | 2001-07-31 | 2003-01-31 | Florida State University Research Foundation, Inc. | C10 carbonate substituted taxanes |
| US20030082229A1 (en) * | 2001-11-01 | 2003-05-01 | Board Of Regents, The University Of Texas Systems | Parenteral chlorambucil for treatment of malignant and autoimmune disease and methods of use |
| SV2006002010A (es) * | 2004-02-13 | 2006-08-23 | Univ Florida State Res Found | Taxanos sustituidos con esteres de ciclopentilo en c10 |
| EP1848423A4 (en) * | 2005-02-14 | 2008-12-31 | Univ Florida State Res Found | C10 CYCLOPROPYL ESTER SUBSTITUTED TAXAN COMPOSITIONS |
| US8242166B2 (en) * | 2008-03-31 | 2012-08-14 | Florida State University Research Foundation, Inc. | C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| US5243045A (en) | 1991-09-23 | 1993-09-07 | Florida State University | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them |
| US5227400A (en) | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
| US5714513A (en) | 1991-09-23 | 1998-02-03 | Florida State University | C10 taxane derivatives and pharmaceutical compositions |
| US5283253A (en) | 1991-09-23 | 1994-02-01 | Florida State University | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them |
| US5350866A (en) | 1991-09-23 | 1994-09-27 | Bristol-Myers Squibb Company | 10-desacetoxytaxol derivatives |
| US5430160A (en) | 1991-09-23 | 1995-07-04 | Florida State University | Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides |
| US5721268A (en) | 1991-09-23 | 1998-02-24 | Florida State University | C7 taxane derivatives and pharmaceutical compositions containing them |
| DE69333675T2 (de) | 1992-01-15 | 2006-02-02 | E.R. Squibb & Sons, Inc. | Enzymatische Verfahren zur Trennung von Enantiomerengemischen von Verbindungen, die als Zwischenprodukte zur Herstellung von Taxanen nützlich sind |
| US5272171A (en) | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| US5698712A (en) | 1992-03-06 | 1997-12-16 | Indena S.P.A. | Baccatine III derivatives |
| US5939561A (en) | 1992-03-10 | 1999-08-17 | Rhone-Poulence Rorer S.A. | Process for the preparation of β-phenylisoserine and β-lactam and their analogues |
| FR2691460B1 (fr) | 1992-05-21 | 1994-07-22 | Rhone Poulenc Rorer Sa | Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent. |
| US5254580A (en) | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
| CA2100808A1 (en) | 1992-10-01 | 1994-04-02 | Vittorio Farina | Deoxy paclitaxels |
| FR2697752B1 (fr) | 1992-11-10 | 1995-04-14 | Rhone Poulenc Rorer Sa | Compositions antitumorales contenant des dérivés du taxane. |
| DE4241664C2 (de) | 1992-12-04 | 1995-04-06 | Borus Spezialverfahren | Elektronisches Lebensdetektionssystem |
| CA2109861C (en) | 1992-12-04 | 1999-03-16 | Shu-Hui Chen | 6,7-modified paclitaxels |
| MX9307777A (es) | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
| NO310238B1 (no) | 1992-12-24 | 2001-06-11 | Bristol Myers Squibb Co | Kjemiske forbindelser og farmasöytisk preparat samt anvendelse av slike preparater |
| FR2702212B1 (fr) | 1993-03-02 | 1995-04-07 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| US5703247A (en) | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
| US5475011A (en) | 1993-03-26 | 1995-12-12 | The Research Foundation Of State University Of New York | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
| IT1261667B (it) | 1993-05-20 | 1996-05-29 | Tassano ad attivita' antitumorale. | |
| ATE249448T1 (de) | 1993-06-11 | 2003-09-15 | Upjohn Co | Delta 6,7-taxol derivate antineoplastische verbindungen und diese enthaltende pharmazeutische zusammenstellungen |
| IL109926A (en) | 1993-06-15 | 2000-02-29 | Bristol Myers Squibb Co | Methods for the preparation of taxanes and microorganisms and enzymes utilized therein |
| TW397866B (en) | 1993-07-14 | 2000-07-11 | Bristol Myers Squibb Co | Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
| CA2129288C (en) | 1993-08-17 | 2000-05-16 | Jerzy Golik | Phosphonooxymethyl esters of taxane derivatives |
| WO1996013495A1 (en) | 1994-10-28 | 1996-05-09 | The Research Foundation Of State University Of New York | Taxoid derivatives, their preparation and their use as antitumor agents |
| US6100411A (en) * | 1994-10-28 | 2000-08-08 | The Research Foundation Of State University Of New York | Taxoid anti-tumor agents and pharmaceutical compositions thereof |
| CA2162759A1 (en) | 1994-11-17 | 1996-05-18 | Kenji Tsujihara | Baccatin derivatives and processes for preparing the same |
| FR2732342B1 (fr) | 1995-04-03 | 1997-04-30 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2732968B1 (fr) | 1995-04-14 | 1997-05-16 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US5801191A (en) | 1995-06-01 | 1998-09-01 | Biophysica Foundation | Taxoids |
| US5780653A (en) | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
| CA2231837A1 (en) | 1995-09-13 | 1997-03-20 | Florida State University | Radiosensitizing taxanes and their pharmaceutical preparations |
| FR2742751B1 (fr) * | 1995-12-22 | 1998-01-30 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2745814B1 (fr) * | 1996-03-06 | 1998-04-03 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| WO1997042181A1 (en) | 1996-05-06 | 1997-11-13 | Florida State University | 1-deoxy baccatin iii, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof |
| JPH1045583A (ja) | 1996-05-14 | 1998-02-17 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
| EP0930309A4 (en) | 1996-07-15 | 2001-09-26 | Yakult Honsha Kk | TAXANE DERIVATIVES AND MEDICINES CONTAINING THEM |
| US5811452A (en) | 1997-01-08 | 1998-09-22 | The Research Foundation Of State University Of New York | Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof |
| US5912264A (en) | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
| US7288665B1 (en) | 1997-08-18 | 2007-10-30 | Florida State University | Process for selective derivatization of taxanes |
| JP2003026673A (ja) | 1999-03-05 | 2003-01-29 | Asahi Kasei Corp | 骨形成促進剤 |
| JP2003522171A (ja) * | 2000-02-02 | 2003-07-22 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | 抗腫瘍剤としてのｃ１０カーボネート置換タキサン |
| BR0104358A (pt) | 2000-02-02 | 2002-01-02 | Univ Florida State Res Found | Formulações de taxana tendo solubilidade aperfeiçoada |
-
2001
- 2001-02-02 JP JP2001557863A patent/JP2003522171A/ja not_active Withdrawn
- 2001-02-02 MX MXPA01009902A patent/MXPA01009902A/es active IP Right Grant
- 2001-02-02 PL PL01350028A patent/PL350028A1/xx not_active Application Discontinuation
- 2001-02-02 GE GEAP20016129A patent/GEP20043239B/en unknown
- 2001-02-02 AU AU33301/01A patent/AU782028B2/en not_active Ceased
- 2001-02-02 US US09/776,274 patent/US6660866B2/en not_active Expired - Fee Related
- 2001-02-02 UA UA2001106731A patent/UA75038C2/uk unknown
- 2001-02-02 EP EP01905420A patent/EP1165550A1/en not_active Withdrawn
- 2001-02-02 HU HU0200759A patent/HUP0200759A3/hu unknown
- 2001-02-02 CN CNB018001483A patent/CN1186340C/zh not_active Expired - Fee Related
- 2001-02-02 TR TR2001/02855T patent/TR200102855T1/xx unknown
- 2001-02-02 IL IL14563601A patent/IL145636A0/xx unknown
- 2001-02-02 CA CA002368151A patent/CA2368151A1/en not_active Abandoned
- 2001-02-02 RU RU2001129533/04A patent/RU2264400C2/ru not_active IP Right Cessation
- 2001-02-02 NZ NZ514074A patent/NZ514074A/xx unknown
- 2001-02-02 CZ CZ20013405A patent/CZ20013405A3/cs unknown
- 2001-02-02 SK SK1363-2001A patent/SK13632001A3/sk unknown
- 2001-02-02 KR KR1020017012590A patent/KR20010111582A/ko not_active Application Discontinuation
- 2001-02-02 RO ROA200101082A patent/RO121269B1/ro unknown
- 2001-02-02 WO PCT/US2001/003588 patent/WO2001057031A1/en active Application Filing
- 2001-02-02 BR BR0104779-5A patent/BR0104779A/pt not_active IP Right Cessation
- 2001-10-01 ZA ZA200108054A patent/ZA200108054B/xx unknown
- 2001-10-01 BG BG105964A patent/BG65298B1/bg unknown
- 2001-10-01 ZA ZA200108058A patent/ZA200108058B/en unknown
- 2001-10-01 NO NO20014753A patent/NO20014753L/no not_active Application Discontinuation
-
2003
- 2003-08-14 HK HK03105846A patent/HK1053472A1/xx not_active IP Right Cessation
- 2003-11-24 US US10/720,615 patent/US7056946B2/en not_active Expired - Fee Related
-
2006
- 2006-01-12 US US11/330,770 patent/US7256213B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |