TR200102855T1 - Antitümör ajanları olarak C10 karbonat ikameli taksanlar. - Google Patents

Antitümör ajanları olarak C10 karbonat ikameli taksanlar.

Info

Publication number
TR200102855T1
TR200102855T1 TR2001/02855T TR200102855T TR200102855T1 TR 200102855 T1 TR200102855 T1 TR 200102855T1 TR 2001/02855 T TR2001/02855 T TR 2001/02855T TR 200102855 T TR200102855 T TR 200102855T TR 200102855 T1 TR200102855 T1 TR 200102855T1
Authority
TR
Turkey
Prior art keywords
antitumor agents
carbonate substituted
substituted taxanes
taxanes
carbonate
Prior art date
Application number
TR2001/02855T
Other languages
English (en)
Inventor
Robert Holton A.
Original Assignee
Florida State University Research Foundation, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Florida State University Research Foundation, Inc filed Critical Florida State University Research Foundation, Inc
Publication of TR200102855T1 publication Critical patent/TR200102855T1/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)

Abstract

C(10)' da bir karbonat ikamesine C(7)' de bir hidroksi ikamesine ve bir C(2), C(9), C(14) ve yan zincir ikameleri araciligina sahip taksanlar.
TR2001/02855T 2000-02-02 2001-02-02 Antitümör ajanları olarak C10 karbonat ikameli taksanlar. TR200102855T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17968400P 2000-02-02 2000-02-02

Publications (1)

Publication Number Publication Date
TR200102855T1 true TR200102855T1 (tr) 2002-06-21

Family

ID=22657547

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02855T TR200102855T1 (tr) 2000-02-02 2001-02-02 Antitümör ajanları olarak C10 karbonat ikameli taksanlar.

Country Status (25)

Country Link
US (3) US6660866B2 (tr)
EP (1) EP1165550A1 (tr)
JP (1) JP2003522171A (tr)
KR (1) KR20010111582A (tr)
CN (1) CN1186340C (tr)
AU (1) AU782028B2 (tr)
BG (1) BG65298B1 (tr)
BR (1) BR0104779A (tr)
CA (1) CA2368151A1 (tr)
CZ (1) CZ20013405A3 (tr)
GE (1) GEP20043239B (tr)
HK (1) HK1053472A1 (tr)
HU (1) HUP0200759A3 (tr)
IL (1) IL145636A0 (tr)
MX (1) MXPA01009902A (tr)
NO (1) NO20014753L (tr)
NZ (1) NZ514074A (tr)
PL (1) PL350028A1 (tr)
RO (1) RO121269B1 (tr)
RU (1) RU2264400C2 (tr)
SK (1) SK13632001A3 (tr)
TR (1) TR200102855T1 (tr)
UA (1) UA75038C2 (tr)
WO (1) WO2001057031A1 (tr)
ZA (2) ZA200108054B (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003522171A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのｃ１０カーボネート置換タキサン
CZ20013498A3 (cs) * 2000-02-02 2002-04-17 Florida State University Research Foundation, Inc. Taxanové formulace mající zlepąenou rozpustnost
US6649632B2 (en) * 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
JP2003522170A (ja) * 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのｃ７カーボネート置換タキサン
CA2354478A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 carbonate substituted taxanes
US20030082229A1 (en) * 2001-11-01 2003-05-01 Board Of Regents, The University Of Texas Systems Parenteral chlorambucil for treatment of malignant and autoimmune disease and methods of use
HN2005000054A (es) * 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
AU2006214498A1 (en) * 2005-02-14 2006-08-24 Florida State University Research Foundation, Inc. C10 cyclopropyl ester substituted taxane compositions
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン

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US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5243045A (en) 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5714513A (en) 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5227400A (en) 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5430160A (en) 1991-09-23 1995-07-04 Florida State University Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
US5350866A (en) 1991-09-23 1994-09-27 Bristol-Myers Squibb Company 10-desacetoxytaxol derivatives
US5283253A (en) 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5721268A (en) 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
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US5272171A (en) 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5698712A (en) 1992-03-06 1997-12-16 Indena S.P.A. Baccatine III derivatives
US5939561A (en) 1992-03-10 1999-08-17 Rhone-Poulence Rorer S.A. Process for the preparation of β-phenylisoserine and β-lactam and their analogues
FR2691460B1 (fr) 1992-05-21 1994-07-22 Rhone Poulenc Rorer Sa Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent.
US5254580A (en) 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
CA2100808A1 (en) 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
FR2697752B1 (fr) 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
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Also Published As

Publication number Publication date
HUP0200759A3 (en) 2002-10-28
SK13632001A3 (sk) 2002-06-04
UA75038C2 (en) 2006-03-15
RU2264400C2 (ru) 2005-11-20
US20040122055A1 (en) 2004-06-24
HK1053472A1 (en) 2003-10-24
EP1165550A1 (en) 2002-01-02
PL350028A1 (en) 2002-10-21
CZ20013405A3 (cs) 2002-03-13
NO20014753L (no) 2001-11-29
KR20010111582A (ko) 2001-12-19
BG65298B1 (bg) 2007-12-28
AU3330101A (en) 2001-08-14
US6660866B2 (en) 2003-12-09
US20060111401A1 (en) 2006-05-25
US20030114493A1 (en) 2003-06-19
MXPA01009902A (es) 2003-07-28
BR0104779A (pt) 2001-12-26
CN1429225A (zh) 2003-07-09
JP2003522171A (ja) 2003-07-22
NO20014753D0 (no) 2001-10-01
ZA200108054B (en) 2003-12-01
US7256213B2 (en) 2007-08-14
HUP0200759A2 (hu) 2002-07-29
CN1186340C (zh) 2005-01-26
AU782028B2 (en) 2005-06-30
CA2368151A1 (en) 2001-08-09
BG105964A (en) 2002-08-30
NZ514074A (en) 2004-03-26
US7056946B2 (en) 2006-06-06
IL145636A0 (en) 2002-06-30
ZA200108058B (en) 2003-12-01
RO121269B1 (ro) 2007-02-28
GEP20043239B (en) 2004-05-25
WO2001057031A1 (en) 2001-08-09

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