PT859612E - Composicao farmaceutica contendo um omeprazol acid-labil e um processo para a sua preparacao - Google Patents
Composicao farmaceutica contendo um omeprazol acid-labil e um processo para a sua preparacaoInfo
- Publication number
- PT859612E PT859612E PT96931211T PT96931211T PT859612E PT 859612 E PT859612 E PT 859612E PT 96931211 T PT96931211 T PT 96931211T PT 96931211 T PT96931211 T PT 96931211T PT 859612 E PT859612 E PT 859612E
- Authority
- PT
- Portugal
- Prior art keywords
- omeprazole
- enteric coating
- layer
- acid
- image
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9511094 | 1995-09-21 | ||
FR9514492A FR2742050A1 (fr) | 1995-12-07 | 1995-12-07 | Nouvelle composition contenant un benzimidazole acido-labile et son procede de preparation |
FR9602265A FR2745181A1 (fr) | 1996-02-23 | 1996-02-23 | Nouvelle composition contenant un benzimidazole acido-labile et son procede de preparation |
FR9605082A FR2747573A1 (fr) | 1996-04-23 | 1996-04-23 | Nouvelle composition contenant un benzimidazole acido-labile et son procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
PT859612E true PT859612E (pt) | 2003-10-31 |
Family
ID=27446956
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00127495T PT1092434E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um benzimidazole acido-labil e processo para a sua preparacao |
PT03001111T PT1308159E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um omeprazole labil a acidos e processo para a sua preparacao |
PT96931211T PT859612E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um omeprazol acid-labil e um processo para a sua preparacao |
PT96931210T PT854718E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um benzimidazole acido-labil e processo para a sua preparacao |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00127495T PT1092434E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um benzimidazole acido-labil e processo para a sua preparacao |
PT03001111T PT1308159E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um omeprazole labil a acidos e processo para a sua preparacao |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96931210T PT854718E (pt) | 1995-09-21 | 1996-09-23 | Composicao farmaceutica contendo um benzimidazole acido-labil e processo para a sua preparacao |
Country Status (19)
Country | Link |
---|---|
US (3) | US6207198B1 (pt) |
EP (4) | EP1308159B1 (pt) |
JP (2) | JP3463266B2 (pt) |
KR (1) | KR100350138B1 (pt) |
CN (1) | CN1093855C (pt) |
AT (4) | ATE286394T1 (pt) |
AU (2) | AU713242B2 (pt) |
CA (1) | CA2231223C (pt) |
CZ (1) | CZ293595B6 (pt) |
DE (4) | DE69631981T2 (pt) |
DK (4) | DK1308159T3 (pt) |
ES (4) | ES2201200T3 (pt) |
HU (1) | HU227566B1 (pt) |
NO (1) | NO320489B1 (pt) |
NZ (1) | NZ318501A (pt) |
PL (1) | PL186605B1 (pt) |
PT (4) | PT1092434E (pt) |
SK (1) | SK284291B6 (pt) |
WO (2) | WO1997012580A2 (pt) |
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FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
GB9710800D0 (en) * | 1997-05-23 | 1997-07-23 | Cipla Limited | Pharmaceutical composition and method of preparing it |
SI9700186B (sl) | 1997-07-14 | 2006-10-31 | Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. | Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin |
FR2774288B1 (fr) | 1998-01-30 | 2001-09-07 | Ethypharm Sa | Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques |
DK173431B1 (da) * | 1998-03-20 | 2000-10-23 | Gea Farmaceutisk Fabrik As | Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs |
ZA9810765B (en) * | 1998-05-28 | 1999-08-06 | Ranbaxy Lab Ltd | Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole. |
PT1105105E (pt) | 1998-08-12 | 2006-07-31 | Altana Pharma Ag | Forma de administracao oral para piridin-2-ilmetilsulfinil-1h-benzimidazois |
US6174902B1 (en) | 1999-04-28 | 2001-01-16 | Sepracor Inc. | R-rabeprazole compositions and methods |
FR2793688B1 (fr) | 1999-05-21 | 2003-06-13 | Ethypharm Lab Prod Ethiques | Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques |
IL130602A0 (en) | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
ES2168043B1 (es) * | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
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SE9402431D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
CZ289804B6 (cs) | 1994-07-08 | 2002-04-17 | Astrazeneca Ab | Multijednotková tabletovaná dávková forma I |
ES2094694B1 (es) | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion. |
US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
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SE9704869D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
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1996
- 1996-09-23 DK DK03001111T patent/DK1308159T3/da active
- 1996-09-23 SK SK314-98A patent/SK284291B6/sk not_active IP Right Cessation
- 1996-09-23 WO PCT/IB1996/001054 patent/WO1997012580A2/en active IP Right Grant
- 1996-09-23 AT AT03001111T patent/ATE286394T1/de active
- 1996-09-23 DE DE69631981T patent/DE69631981T2/de not_active Expired - Lifetime
- 1996-09-23 DK DK96931211T patent/DK0859612T3/da active
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- 1996-09-23 HU HU9900467A patent/HU227566B1/hu not_active IP Right Cessation
- 1996-09-23 EP EP03001111A patent/EP1308159B1/en not_active Expired - Lifetime
- 1996-09-23 ES ES96931211T patent/ES2201200T3/es not_active Expired - Lifetime
- 1996-09-23 DK DK00127495T patent/DK1092434T3/da active
- 1996-09-23 US US09/043,145 patent/US6207198B1/en not_active Expired - Lifetime
- 1996-09-23 EP EP96931211A patent/EP0859612B1/en not_active Expired - Lifetime
- 1996-09-23 PT PT00127495T patent/PT1092434E/pt unknown
- 1996-09-23 CN CN96197132A patent/CN1093855C/zh not_active Expired - Fee Related
- 1996-09-23 CZ CZ1998879A patent/CZ293595B6/cs not_active IP Right Cessation
- 1996-09-23 PL PL96325838A patent/PL186605B1/pl not_active IP Right Cessation
- 1996-09-23 AT AT00127495T patent/ATE262332T1/de active
- 1996-09-23 DE DE69634160T patent/DE69634160T2/de not_active Expired - Lifetime
- 1996-09-23 DE DE69631834T patent/DE69631834T2/de not_active Expired - Lifetime
- 1996-09-23 AU AU69988/96A patent/AU713242B2/en not_active Ceased
- 1996-09-23 US US09/043,663 patent/US6159499A/en not_active Expired - Lifetime
- 1996-09-23 EP EP96931210A patent/EP0854718B1/en not_active Expired - Lifetime
- 1996-09-23 DE DE69628444T patent/DE69628444T2/de not_active Expired - Lifetime
- 1996-09-23 ES ES96931210T patent/ES2220989T3/es not_active Expired - Lifetime
- 1996-09-23 ES ES00127495T patent/ES2218054T3/es not_active Expired - Lifetime
- 1996-09-23 PT PT03001111T patent/PT1308159E/pt unknown
- 1996-09-23 AT AT96931210T patent/ATE261303T1/de active
- 1996-09-23 JP JP51410897A patent/JP3463266B2/ja not_active Expired - Fee Related
- 1996-09-23 JP JP51410797A patent/JP3198337B2/ja not_active Expired - Fee Related
- 1996-09-23 AU AU69987/96A patent/AU6998796A/en not_active Abandoned
- 1996-09-23 PT PT96931211T patent/PT859612E/pt unknown
- 1996-09-23 DK DK96931210T patent/DK0854718T3/da active
- 1996-09-23 WO PCT/IB1996/001055 patent/WO1997012581A2/en active IP Right Grant
- 1996-09-23 EP EP00127495A patent/EP1092434B1/en not_active Expired - Lifetime
- 1996-09-23 ES ES03001111T patent/ES2236628T3/es not_active Expired - Lifetime
- 1996-09-23 PT PT96931210T patent/PT854718E/pt unknown
- 1996-09-23 KR KR10-1998-0701884A patent/KR100350138B1/ko not_active IP Right Cessation
- 1996-09-23 AT AT96931211T patent/ATE241357T1/de active
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1998
- 1998-03-20 NO NO19981284A patent/NO320489B1/no not_active IP Right Cessation
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1999
- 1999-12-30 US US09/538,845 patent/US6248355B1/en not_active Expired - Lifetime
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