PT831098E - Intermediarios e processo para a preparacao de olanzapina - Google Patents

Intermediarios e processo para a preparacao de olanzapina

Info

Publication number
PT831098E
PT831098E PT97307383T PT97307383T PT831098E PT 831098 E PT831098 E PT 831098E PT 97307383 T PT97307383 T PT 97307383T PT 97307383 T PT97307383 T PT 97307383T PT 831098 E PT831098 E PT 831098E
Authority
PT
Portugal
Prior art keywords
olanzapine
intermediaries
preparation
Prior art date
Application number
PT97307383T
Other languages
English (en)
Portuguese (pt)
Inventor
Samuel Dean Larsen
Gregory Alan Stephenson
Charles Arthur Bunnell
John Richard Nichols
Susan Marie Reutzel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT831098(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT831098E publication Critical patent/PT831098E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT97307383T 1996-09-23 1997-09-22 Intermediarios e processo para a preparacao de olanzapina PT831098E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2648796P 1996-09-23 1996-09-23

Publications (1)

Publication Number Publication Date
PT831098E true PT831098E (pt) 2002-04-29

Family

ID=21832120

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97307383T PT831098E (pt) 1996-09-23 1997-09-22 Intermediarios e processo para a preparacao de olanzapina

Country Status (35)

Country Link
US (1) US6020487A (h)
EP (1) EP0831098B1 (h)
JP (2) JP2001500877A (h)
KR (1) KR100560015B1 (h)
CN (1) CN1122036C (h)
AR (1) AR013838A1 (h)
AT (1) ATE209208T1 (h)
AU (1) AU719441B2 (h)
BR (1) BR9712100A (h)
CA (1) CA2265712C (h)
CO (1) CO4910140A1 (h)
CZ (1) CZ299248B6 (h)
DE (1) DE69708428T2 (h)
DK (1) DK0831098T3 (h)
EA (1) EA001642B1 (h)
EG (1) EG23861A (h)
ES (1) ES2166051T3 (h)
HU (1) HU226484B1 (h)
ID (1) ID27275A (h)
IL (1) IL128962A (h)
IN (1) IN187156B (h)
MY (1) MY125565A (h)
NO (1) NO323980B1 (h)
NZ (1) NZ334448A (h)
PE (1) PE110398A1 (h)
PL (3) PL196068B1 (h)
PT (1) PT831098E (h)
RS (1) RS49598B (h)
SI (1) SI0831098T1 (h)
SV (1) SV1997000081A (h)
TR (1) TR199900640T2 (h)
TW (1) TW470746B (h)
UA (1) UA59371C2 (h)
WO (1) WO1998012199A1 (h)
ZA (1) ZA978515B (h)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004507548A (ja) * 2000-08-31 2004-03-11 ドクター・レディーズ・ラボラトリーズ・リミテッド オランザピン水和物の調製方法、及びこれを結晶形態のオランザピンに変換する方法
US6740753B2 (en) * 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
AU2002340328A1 (en) * 2001-10-29 2003-05-12 Janet I. Cord Olanzapine dihydrate-ii a process for its preparation and use thereof
JP4530664B2 (ja) 2001-12-24 2010-08-25 サン・ファーマシューティカル・インダストリーズ・リミテッド ２−メチル−４−（４−メチル−１−ピペラジニル）−１０Ｈ−チエノ［２，３−ｂ］［１，５］ベンゾジアゼピンの結晶形Ｉ、この結晶形Ｉの製造方法、及び医薬組成物
AU2003243153A1 (en) * 2002-04-23 2003-11-10 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
AU2003237305A1 (en) * 2002-05-31 2003-12-19 Geneva Pharmaceuticals, Inc. Process of preparation of olanzapine form i
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
JP2007511605A (ja) * 2003-11-18 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー オランザピン含有経皮薬物送達組成物
JP2007515428A (ja) * 2003-12-22 2007-06-14 テバ ファーマシューティカル インダストリーズ リミティド オランザピンの合成方法
WO2005070938A1 (en) 2004-01-27 2005-08-04 Synthon B.V. Stable salts of olanzapine
US20070072845A1 (en) * 2004-02-19 2007-03-29 Davuluri Rammohan Rao Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2006006185A1 (en) * 2004-07-14 2006-01-19 Shasun Chemicals And Drugs Limited Improved process for making form i of olanzapine.
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
US7829700B2 (en) 2004-09-06 2010-11-09 Shasun Chemicals And Drugs Limited Process for preparation of a pharmaceutically pure polymorphic form I of Olanzapine
KR20130030305A (ko) * 2004-11-16 2013-03-26 엘란 파마 인터내셔널 리미티드 주사가능한 나노입자형 올란자핀 제형
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
EP0582368B1 (en) * 1992-05-29 2001-01-24 Eli Lilly And Company Limited Thienobenzodiazepine derivatives for treatment of CNS disorders
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
IL128956A0 (en) * 1996-09-23 2000-02-17 Lilly Co Eli Olanzapine dihydrate D

Also Published As

Publication number Publication date
ID27275A (id) 2001-03-22
WO1998012199A1 (en) 1998-03-26
NZ334448A (en) 2000-08-25
HU226484B1 (en) 2009-03-02
JP2009242407A (ja) 2009-10-22
UA59371C2 (uk) 2003-09-15
ATE209208T1 (de) 2001-12-15
KR20000048520A (ko) 2000-07-25
PL332482A1 (en) 1999-09-13
TR199900640T2 (xx) 1999-06-21
CA2265712C (en) 2006-10-31
EP0831098B1 (en) 2001-11-21
US6020487A (en) 2000-02-01
KR100560015B1 (ko) 2006-03-15
CA2265712A1 (en) 1998-03-26
EA199900326A1 (ru) 1999-08-26
EA001642B1 (ru) 2001-06-25
IL128962A0 (en) 2000-02-17
NO991382L (no) 1999-03-22
EP0831098A3 (en) 1998-04-29
CO4910140A1 (es) 2000-04-24
ES2166051T3 (es) 2002-04-01
YU15599A (sh) 2001-12-26
DK0831098T3 (da) 2002-05-21
EG23861A (en) 2007-11-18
DE69708428D1 (de) 2002-01-03
CZ299248B6 (cs) 2008-05-28
EP0831098A2 (en) 1998-03-25
JP2001500877A (ja) 2001-01-23
SI0831098T1 (en) 2002-04-30
PL196069B1 (pl) 2007-12-31
SV1997000081A (es) 1999-01-14
HUP0000066A3 (en) 2000-11-28
AU719441B2 (en) 2000-05-11
HUP0000066A2 (hu) 2000-06-28
RS49598B (sr) 2007-06-04
ZA978515B (en) 1999-03-23
DE69708428T2 (de) 2002-07-04
CN1234802A (zh) 1999-11-10
PE110398A1 (es) 1999-01-14
IN187156B (h) 2002-02-16
MY125565A (en) 2006-08-30
PL194565B1 (pl) 2007-06-29
CZ99099A3 (cs) 1999-11-17
TW470746B (en) 2002-01-01
BR9712100A (pt) 1999-08-31
HK1009807A1 (en) 1999-06-11
AR013838A1 (es) 2001-01-31
NO323980B1 (no) 2007-07-30
CN1122036C (zh) 2003-09-24
AU4484197A (en) 1998-04-14
NO991382D0 (no) 1999-03-22
PL196068B1 (pl) 2007-12-31
IL128962A (en) 2003-01-12

Similar Documents

Publication Publication Date Title
PT831098E (pt) Intermediarios e processo para a preparacao de olanzapina
BR9710457A (pt) Processo para a prepara-Æo de ciclohexanodimetanol
BR9711020A (pt) Composi-Æo aquosa de xanpu e processo para fabricar a composi-Æo aquosa de xampu
BR9505754A (pt) Processo para a preparação de copolímeros de poliéster
PT770615E (pt) Processo para a preparacao de di-haloazolopirimidinas
BR9706465A (pt) Processo para a preparação contínua de metilmercaptano
PT909270E (pt) Processo para a preparacao de 2,4-dihidroxipiridina e de 2,4-dihidroxi-3-nitropiridina
BR9500613A (pt) Processo para a preparação contínua de mononitrotoluenos
BR9507494A (pt) Processo para a preparação de famciclovi de 2-amino-6-cloro purina e processo para a preparação de penciclovi de 2-amino-6- cloro purina
BR9607413A (pt) Processo para produçao de pentafluoretano e tetrafluorcloroetano
BR9800557A (pt) Processo contínuo para preparação de 4-aminopiperidinas
PT877738E (pt) Processo para a preparacao de derivados de fenil-imidazolidina
PT925292E (pt) Processos e intermediarios para a preparacao de derivados de cromanol substituido
BR9505251A (pt) Processo para a fabricação de um composto e composto obtido
BR9408530A (pt) Intermediário e processo para preparação
BR9612457A (pt) Processo para a fabricação de felodipina
BR9711732A (pt) Processo para a prepara-Æo de alfa -mega-amino-nitrilas alif ticas
PT915874E (pt) Processo de preparacao de valaciclovir e intermediarios relevantes
BR9707173A (pt) Processo para a preparação de um composto e composto
PT803576E (pt) Processo para a preparacao de lipstatina e de tetra-hidrolipstatina
BR9706239A (pt) Processo para preparação de 3-(1-hidroxifenil-1-alcoxiimino-metil)dioxazinas
PT1012152E (pt) Processo para a preparacao de oxazafosforina-2-aminas
BR9501539A (pt) Processo para a preparação de ácido 3-mercaptopropiônico e 3-mercaptopropionitrila
BR9804794A (pt) Processo para prepara-Æo de 1-alquil-4-(2-cloro-3-alcÄxi-4-alquil-sulfonil-benzoil) -5-hidrÄxi-pirazol e compostos relacioonados
BR9602731A (pt) Processo para a preparação de hidroxibiarilfosfinas e hidroxibiarilfosfina assim obtidas