PT3281939T - Combinação contendo um cristal estável de compostos de 4-oxoquinolina - Google Patents

Combinação contendo um cristal estável de compostos de 4-oxoquinolina

Info

Publication number
PT3281939T
PT3281939T PT171866742T PT17186674T PT3281939T PT 3281939 T PT3281939 T PT 3281939T PT 171866742 T PT171866742 T PT 171866742T PT 17186674 T PT17186674 T PT 17186674T PT 3281939 T PT3281939 T PT 3281939T
Authority
PT
Portugal
Prior art keywords
stable crystal
producing stable
oxoquinoline compound
oxoquinoline
compound
Prior art date
Application number
PT171866742T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3281939(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of PT3281939T publication Critical patent/PT3281939T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
PT171866742T 2004-05-20 2005-05-19 Combinação contendo um cristal estável de compostos de 4-oxoquinolina PT3281939T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004150979 2004-05-20

Publications (1)

Publication Number Publication Date
PT3281939T true PT3281939T (pt) 2023-11-22

Family

ID=35079161

Family Applications (2)

Application Number Title Priority Date Filing Date
PT171866742T PT3281939T (pt) 2004-05-20 2005-05-19 Combinação contendo um cristal estável de compostos de 4-oxoquinolina
PT05726243T PT1636190E (pt) 2004-05-20 2005-05-19 Cristal estável de compostos de 4-oxoquinolina

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT05726243T PT1636190E (pt) 2004-05-20 2005-05-19 Cristal estável de compostos de 4-oxoquinolina

Country Status (33)

Country Link
US (7) US7635704B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (4) EP4299563A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3754064B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR20080064909A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1956961B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (2) AR049280A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2005245296B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE2024C511I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BRPI0510114B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2566922C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (4) CY1113010T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK3281939T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES2960824T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (2) FI3281939T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR23C1040I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HR (2) HRP20231588T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HUE064615T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL179250A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LT (1) LT3281939T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LUC00334I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MXPA06013405A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY134672A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (8) NO339223B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ551839A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PE (2) PE20120361A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (2) PL3281939T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (2) PT3281939T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RS (2) RS52375B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2330845C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (2) SI3281939T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI329015B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2005113508A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA200610647B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6891227B2 (en) 2002-03-20 2005-05-10 International Business Machines Corporation Self-aligned nanotube field effect transistor and method of fabricating same
AR042095A1 (es) * 2002-11-20 2005-06-08 Japan Tobacco Inc Compuesto 4-oxoquinolina y aplicacion del mismo como inhibidor de integrasa de vih
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2007063869A1 (ja) * 2005-11-30 2007-06-07 Japan Tobacco Inc. 高純度キノロン化合物の製造方法
NZ569576A (en) 2005-12-30 2011-09-30 Gilead Sciences Inc Methods for improving the pharmacokinetics of HIV integrase inhibitors
AU2013203476C1 (en) * 2005-12-30 2016-11-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
US20090233964A1 (en) * 2005-12-30 2009-09-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
WO2007089030A1 (en) 2006-02-01 2007-08-09 Japan Tobacco Inc. Use of 6-(3-chloro-2-fluorobenzyl)-1-[(2s)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or salt thereof for treating retrovirus infection
WO2007092802A1 (en) * 2006-02-09 2007-08-16 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and gs 9137
CN101437801B (zh) 2006-03-06 2013-02-06 日本烟草产业株式会社 制备4-氧代喹啉化合物的方法
BRPI0708685B8 (pt) 2006-03-06 2021-05-25 Japan Tobacco Inc composto de 4-oxoquinolina, seu uso e método para produção dos mesmos
US7939553B2 (en) 2006-07-07 2011-05-10 Gilead Sciences, Inc. Modulators of pharmacokinetic properties of therapeutics
WO2008033836A2 (en) 2006-09-12 2008-03-20 Gilead Sciences, Inc. Process and intermediates for preparing integrase inhibitors
MX2009008935A (es) * 2007-02-23 2009-11-02 Gilead Sciences Inc Moduladores de las propiedades farmacocineticas de productos terapeuticos.
AR067184A1 (es) * 2007-06-29 2009-09-30 Gilead Sciences Inc Uso de 6-(3-cloro-2-fluorbencil)-1-[(2s)-1-hidroxi-3-metilbutan-2-il]-7-metoxi-4-oxo-1,4-dihidroquinolina-3-carboxilico. composicion farmaceutica
CN101686972B (zh) * 2007-06-29 2013-08-14 吉里德科学公司 治疗用组合物和方法
AR068403A1 (es) * 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
JP5722213B2 (ja) 2008-05-02 2015-05-20 ギリアード サイエンシーズ, インコーポレイテッド 医薬薬剤の加工性を改良するための固体担体粒子の使用
MX2011008289A (es) 2009-02-06 2011-09-15 Gilead Sciences Inc Tabletas para terapia combinada.
WO2010137032A2 (en) * 2009-05-14 2010-12-02 Matrix Laboratories Ltd. Novel polymorphic forms of elvitegravir and its pharmaceutically acceptable salts
WO2011004389A2 (en) * 2009-06-18 2011-01-13 Matrix Laboratories Ltd An improved process for the preparation of elvitegravir
CN102212032B (zh) * 2011-04-20 2013-07-31 复旦大学 一种5-羟基喹诺酮类衍生物及其制备方法和用途
CN104797555B (zh) 2012-07-06 2017-12-22 基因泰克公司 N‑取代的苯甲酰胺及其使用方法
BR112015002275A2 (pt) 2012-08-03 2017-07-04 Gilead Sciences Inc processos e intermediários para a preparação de inibidores da integrase
CN103819402B (zh) * 2012-11-17 2016-03-30 上海迪赛诺化学制药有限公司 埃替拉韦中间体及其制备方法和应用
CN103864682B (zh) * 2012-12-18 2016-12-28 上海迪赛诺化学制药有限公司 一种制备iii型埃替拉韦晶体的方法
PL2822954T3 (pl) 2012-12-21 2016-09-30 Policykliczne związki karbamoilopirydonu i ich farmaceutyczne zastosowanie
NO2865735T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2013-07-12 2018-07-21
EP3019503B1 (en) 2013-07-12 2017-09-06 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their use for the treatment of hiv infections
CN105315203A (zh) * 2014-06-06 2016-02-10 上海迪赛诺化学制药有限公司 一种v型埃替拉韦晶体及其制备方法
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
NO2717902T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2014-06-20 2018-06-23
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
NZ735575A (en) 2015-04-02 2018-11-30 Gilead Sciences Inc Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
CN106008195B (zh) * 2016-05-19 2018-08-03 绍兴文理学院 一种2,4-二氟-5-碘苯甲酸的制备方法
EP3984536B1 (en) * 2020-10-19 2025-06-25 Centre national de la recherche scientifique Inhibition of the hiv-1 replication by compounds directed against a new target of the viral cycle

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472859A (en) * 1966-11-01 1969-10-14 Sterling Drug Inc 1-alkyl-1,4-dihydro-4-oxo-3 quinoline-carboxylic acids and esters
JPS567162B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-09-14 1981-02-16
JPS4826772A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-08-11 1973-04-09
JPS6450979A (en) 1987-08-21 1989-02-27 Hitachi Shipbuilding Eng Co Method for discriminating whistle sound
JPH0651229B2 (ja) 1989-07-31 1994-07-06 新日本製鐵株式会社 プラズマアーク溶接方法および装置
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
NO304832B1 (no) * 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
JP2993316B2 (ja) 1992-05-27 1999-12-20 宇部興産株式会社 アリール基又は複素芳香環基置換アミノキノロン誘導体及びエイズ治療剤
JPH06199835A (ja) 1993-01-08 1994-07-19 Hokuriku Seiyaku Co Ltd 8−ジフルオロメトキシキノリン−3−カルボン酸誘導体
JPH06271568A (ja) 1993-03-22 1994-09-27 Hokuriku Seiyaku Co Ltd 7−フェニルピペラジニルキノリン−3−カルボン酸誘導体
HUT76643A (en) * 1994-07-18 1997-10-28 Sankyo Co Trifluoromethylquinolinecarboxylic acid derivative, pharmaceutical compositions containing them and their use
JP2930539B2 (ja) 1994-07-18 1999-08-03 三共株式会社 トリフルオロメチルキノリンカルボン酸誘導体
JPH0826772A (ja) 1994-07-22 1996-01-30 Sony Corp 融着用ガラス、その製造方法及び製造装置、並びに磁気ヘッドの製造方法
ES2171260T3 (es) 1996-04-12 2002-09-01 Us Gov Health & Human Serv Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos.
FR2761687B1 (fr) * 1997-04-08 2000-09-15 Centre Nat Rech Scient Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques
JP3776203B2 (ja) 1997-05-13 2006-05-17 第一製薬株式会社 Icam−1産生阻害剤
GB9721964D0 (en) * 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines
US6399629B1 (en) 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
SE9802549D0 (sv) * 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
US6248736B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company 4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
US6248739B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company Quinolinecarboxamides as antiviral agents
PE20011349A1 (es) 2000-06-16 2002-01-19 Upjohn Co 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US6559145B2 (en) * 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
ES2274913T3 (es) 2000-10-12 2007-06-01 MERCK & CO., INC. Aza y poliaza-naftalenil carboxamidas utiles como inhibidores de vih integrada.
EP1333831A2 (en) 2000-10-12 2003-08-13 Merck & Co., Inc. Aza-and polyaza-naphthalenyl ketones useful as hiv integrase inhibitors
WO2002070486A1 (fr) * 2001-03-01 2002-09-12 Shionogi & Co., Ltd. Composes d'heteroaryle azote exerçant un effet inhibiteur sur l'integrase du vih
JP2002293745A (ja) 2001-03-29 2002-10-09 St Marianna Univ School Of Medicine 慢性関節リウマチ治療剤
US20030138483A1 (en) * 2001-05-25 2003-07-24 Sergio Petriconi Soft elastic capsules and compositions thereof
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
FR2827600A1 (fr) 2001-07-20 2003-01-24 Lipha Derives acides de quinolone et leurs applications en therapeutique
RU2206564C1 (ru) * 2002-03-07 2003-06-20 Общество с ограниченной ответственностью "Поливит" Способ получения этилового эфира 6-фтор-7-хлор-1,4-дигидро-4-оксо-3-хинолинкарбоновой кислоты
JP4035765B2 (ja) 2002-10-31 2008-01-23 横河電機株式会社 フーリエ変換型赤外線分光計
AR042095A1 (es) * 2002-11-20 2005-06-08 Japan Tobacco Inc Compuesto 4-oxoquinolina y aplicacion del mismo como inhibidor de integrasa de vih
JP3567162B1 (ja) 2002-11-20 2004-09-22 日本たばこ産業株式会社 4−オキソキノリン化合物及びそのhivインテグラーゼ阻害剤としての利用
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2005113509A1 (en) * 2004-05-20 2005-12-01 Japan Tobacco Inc. Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
EP2332538A1 (en) * 2004-05-21 2011-06-15 Japan Tobacco, Inc. Combinations comprising a 4-isoquinolone derivative and anti-HIV agents

Also Published As

Publication number Publication date
PE20060358A1 (es) 2006-05-12
NO20161297A1 (no) 2007-02-07
HRP20120681T1 (hr) 2012-09-30
ES2388441T3 (es) 2012-10-15
PL3281939T3 (pl) 2024-03-18
NO20065790L (no) 2007-02-07
HK1083341A1 (en) 2006-06-30
PT1636190E (pt) 2012-08-20
CA2566922A1 (en) 2005-12-01
JP3754064B2 (ja) 2006-03-08
ES2960824T3 (es) 2024-03-06
RU2330845C1 (ru) 2008-08-10
NO20230913A1 (no) 2007-02-07
HRP20231588T3 (hr) 2024-03-15
US20190185433A1 (en) 2019-06-20
US7635704B2 (en) 2009-12-22
RS52375B (en) 2012-12-31
CA2566922C (en) 2011-01-11
US20250091995A1 (en) 2025-03-20
LUC00334I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2024-07-01
JP2006001927A (ja) 2006-01-05
US20100204271A1 (en) 2010-08-12
EP4299563A3 (en) 2024-02-28
SI1636190T1 (sl) 2012-09-28
CY1113010T1 (el) 2016-04-13
EP3281939A1 (en) 2018-02-14
AR049280A1 (es) 2006-07-12
CN1956961B (zh) 2010-05-26
KR20080064909A (ko) 2008-07-09
DK1636190T3 (da) 2012-09-24
MY134672A (en) 2007-12-31
AR096100A2 (es) 2015-12-09
NO20240384A1 (no) 2007-02-07
EP4299563A2 (en) 2024-01-03
US8981103B2 (en) 2015-03-17
NO20200873A1 (no) 2007-02-07
SI3281939T1 (sl) 2024-02-29
CY2024008I1 (el) 2024-09-20
TWI329015B (en) 2010-08-21
PE20120361A1 (es) 2012-05-03
US20180029989A1 (en) 2018-02-01
NO339223B1 (no) 2016-11-21
LT3281939T (lt) 2023-11-27
ZA200610647B (en) 2008-06-25
US20150361044A1 (en) 2015-12-17
FIC20240008I1 (fi) 2024-03-20
IL179250A0 (en) 2007-03-08
NO20190051A1 (no) 2007-02-07
RS64845B1 (sr) 2023-12-29
HUE064615T2 (hu) 2024-04-28
FR23C1040I1 (fr) 2023-12-29
BRPI0510114B8 (pt) 2021-05-25
NO20220690A1 (no) 2007-02-07
MXPA06013405A (es) 2007-03-01
NO347902B1 (no) 2024-05-06
EP1636190A1 (en) 2006-03-22
CY1126560T1 (el) 2024-09-20
CY2015009I2 (el) 2024-09-20
PL1636190T3 (pl) 2012-10-31
NO2024034I1 (no) 2024-07-15
EP2514746A1 (en) 2012-10-24
US20220235009A1 (en) 2022-07-28
AU2005245296A1 (en) 2005-12-01
NZ551839A (en) 2009-11-27
FI3281939T3 (fi) 2023-10-23
EP3281939B1 (en) 2023-10-18
US20060030710A1 (en) 2006-02-09
HUS2400006I1 (hu) 2024-04-28
WO2005113508A1 (en) 2005-12-01
EP1636190B1 (en) 2012-06-27
TW200600097A (en) 2006-01-01
CN1956961A (zh) 2007-05-02
BRPI0510114A (pt) 2007-09-25
BE2024C511I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2024-10-08
DK3281939T3 (da) 2024-01-22
AU2005245296B2 (en) 2010-08-12
CY2024008I2 (el) 2024-09-20
BRPI0510114B1 (pt) 2020-09-15
CY2015009I1 (el) 2024-09-20

Similar Documents

Publication Publication Date Title
PT3281939T (pt) Combinação contendo um cristal estável de compostos de 4-oxoquinolina
IL180742A0 (en) Method of manufacture
IL181303A0 (en) Method for the production of dihydropteridinones
IL180854A (en) Methods for producing antibodies against vegf
EG25686A (en) Method of producing aminophenol compounds
PL1767528T3 (pl) Sposób wytwarzania związku 5-hydroksy-4-tiometylopirazolowego
EP1813678A4 (en) GLYCOGEN SYNTHESIS METHOD
IL182544A0 (en) Production method of pyrimidine compounds
EP1713719A4 (en) METHOD FOR PRODUCING HYDROGEN
IL176722A0 (en) Method of producing salts of dinitramidic acid
EP1776948A4 (en) METHOD FOR PRODUCING LIPOSO-CONTAINING PREPARATION
GB2416597B (en) Method of manufacturing domain inverted crystal
EP1764416A4 (en) PROCESS FOR THE MANUFACTURE OF THEANIN
SI1794111T1 (sl) Postopek za pridobivanje ciklopentanona
IL181339A0 (en) Method for the production of diarylcycloalkyl derivatives
IL191826A0 (en) Method for producing purified formylcyclopropane compound and intermediate of such formylcyclopropane compound
PL370547A1 (pl) Sposób wytwarzania poliestroli o budowie rozgałęzionej
PL367920A1 (en) Method for manufacture of oligoetheroles
GB0414159D0 (en) Process for manufacture of microbeads
GEU20041064U (en) Method for production of Matsoni
PL378312A1 (pl) Sposób wytwarzania tert-butyloacetylenu
ZA200700282B (en) Method for the production of dihydropteridinones
PL370044A1 (pl) Sposób wytwarzania elementów dekoracyjnych
PL369884A1 (pl) Sposób wytwarzania podstawionych cyjanowinylooksiranów
HUP0401136A3 (en) Method for post-blinding of gas-plumbing