PT2389937T - Composição farmacêutica para melhorar as funções cerebrais - Google Patents

Composição farmacêutica para melhorar as funções cerebrais

Info

Publication number
PT2389937T
PT2389937T PT11006318T PT11006318T PT2389937T PT 2389937 T PT2389937 T PT 2389937T PT 11006318 T PT11006318 T PT 11006318T PT 11006318 T PT11006318 T PT 11006318T PT 2389937 T PT2389937 T PT 2389937T
Authority
PT
Portugal
Prior art keywords
cerebral
ingredient
integer
optionally substituted
hydroxyl group
Prior art date
Application number
PT11006318T
Other languages
English (en)
Inventor
Ono Satoshi
Nakagawa Masaya
Nakada Yasushi
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of PT2389937T publication Critical patent/PT2389937T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
PT11006318T 2002-06-14 2003-04-03 Composição farmacêutica para melhorar as funções cerebrais PT2389937T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002173483 2002-06-14

Publications (1)

Publication Number Publication Date
PT2389937T true PT2389937T (pt) 2018-10-26

Family

ID=29727916

Family Applications (2)

Application Number Title Priority Date Filing Date
PT11006318T PT2389937T (pt) 2002-06-14 2003-04-03 Composição farmacêutica para melhorar as funções cerebrais
PT03760132T PT1514542E (pt) 2002-06-14 2003-04-03 Composição medicamentosa incluindo tacrina ou donepezilo para melhorar as funções cerebrais

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT03760132T PT1514542E (pt) 2002-06-14 2003-04-03 Composição medicamentosa incluindo tacrina ou donepezilo para melhorar as funções cerebrais

Country Status (23)

Country Link
US (3) USRE42327E1 (pt)
EP (2) EP1514542B1 (pt)
JP (1) JP4675103B2 (pt)
KR (1) KR100935615B1 (pt)
CN (1) CN100375619C (pt)
AT (1) ATE546140T1 (pt)
AU (1) AU2003236364C1 (pt)
BR (1) BRPI0311780B8 (pt)
CA (1) CA2488120C (pt)
CY (2) CY1112958T1 (pt)
DK (2) DK2389937T3 (pt)
ES (2) ES2685923T3 (pt)
HU (1) HUE041842T2 (pt)
IL (1) IL165589A (pt)
MX (1) MXPA04012534A (pt)
NO (1) NO333504B1 (pt)
NZ (1) NZ537090A (pt)
PL (1) PL217394B1 (pt)
PT (2) PT2389937T (pt)
SI (2) SI2389937T1 (pt)
TR (1) TR201816386T4 (pt)
WO (1) WO2003105830A1 (pt)
ZA (1) ZA200409901B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0213393B8 (pt) * 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
CN100375619C (zh) 2002-06-14 2008-03-19 富山化学工业株式会社 改善脑功能的药物组合物及其用途
CA2521648C (en) * 2003-04-17 2012-07-03 Toyama Chemical Co., Ltd. Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
US7435837B2 (en) 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
EP2258358A3 (en) * 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
MX2008013728A (es) * 2006-04-26 2009-01-07 Toyama Chemical Co Ltd Inductor de neurogenesis o agente terapeutico de neuropatia que abarca el derivado del eter alkilico o sal del mismo.
US8119625B2 (en) * 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
SI2048145T1 (sl) * 2006-08-04 2011-04-29 Toyama Chemical Co Ltd Spodbujevalec aktivnosti proteinske kinaze c, vsebujoäś derivat alkilnega etra ali sol le-tega
US20090221554A1 (en) * 2008-02-28 2009-09-03 Zenyaku Kogyo Kabushiki Kaisha Method of treating cognitive impairment
CN102046620B (zh) * 2008-05-28 2014-04-09 富山化学工业株式会社 新的苯并噻吩氧化物衍生物及其盐
ES2694202T3 (es) 2012-07-12 2018-12-19 Concert Pharmaceuticals, Inc. Idebenona deuterada
EP3100725B1 (en) * 2014-01-31 2020-05-06 FUJIFILM Toyama Chemical Co., Ltd. Post nerve injury rehabilitation effect-enhancing agent comprising an alkyl ether derivative or a salt thereof
BR112019024851A2 (pt) * 2017-06-02 2020-06-09 Fujifilm Toyama Chemical Co Ltd agente para evitar ou tratar atrofia cerebral
EP3632430A4 (en) 2017-06-02 2020-06-10 FUJIFILM Toyama Chemical Co., Ltd. AGENT FOR THE PREVENTION OR TREATMENT OF SPINOCEREBELLOUS ATAXIA
KR20200003102A (ko) 2017-06-02 2020-01-08 후지필름 도야마 케미컬 가부시키가이샤 아밀로이드 β 단백질량 감소제
JP7370859B2 (ja) 2017-06-02 2023-10-30 富士フイルム富山化学株式会社 タウオパチー予防または治療剤
JPWO2018221728A1 (ja) * 2017-06-02 2020-04-02 富士フイルム富山化学株式会社 アルツハイマー型認知症予防または治療剤
SG11202000193UA (en) * 2017-07-08 2020-02-27 Massachusetts Gen Hospital Screening platform to identify therapeutic drugs or agents for treatment of alzheimer's disease
EP3705121B1 (en) 2017-10-30 2023-08-30 FUJIFILM Toyama Chemical Co., Ltd. Emopamil binding protein binding agent and use thereof
CN110464834B (zh) * 2019-09-04 2022-12-02 北京豪思生物科技股份有限公司 铜蓝蛋白联合多奈哌齐的应用
KR20220040291A (ko) 2020-09-23 2022-03-30 씨엔지바이오 주식회사 4-메톡시-2-펜에틸이소인돌린-1-온 유도체 및 이를 포함하는 신경질환의 치료용 조성물
KR20220040294A (ko) 2020-09-23 2022-03-30 씨엔지바이오 주식회사 6-메톡시-2-펜에틸이소인돌린-1-온 유도체 및 이를 포함하는 신경질환의 치료용 조성물

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74497A (en) 1985-03-05 1990-02-09 Proterra Ag Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives
US5177082A (en) 1985-11-05 1993-01-05 Yu Chao Mei Huperzines and analogs
US4663318A (en) 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
JPH0210827A (ja) 1988-06-29 1990-01-16 Matsushita Electron Corp 半導体装置の製造方法
US5280032A (en) 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
JP2887492B2 (ja) 1990-02-05 1999-04-26 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
JP2913196B2 (ja) 1989-04-26 1999-06-28 富山化学工業株式会社 1,2−エタンジオール誘導体またはその塩
NZ232493A (en) * 1989-02-14 1992-06-25 Toyama Chemical Co Ltd Aryl- or heterocyclyl-substituted 1,2-ethanediol derivatives and pharmaceutical compositions
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
JP3044055B2 (ja) 1990-08-09 2000-05-22 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
JPH0676401B2 (ja) 1990-10-19 1994-09-28 エスエス製薬株式会社 キノリン誘導体及びこれを含有する医薬
TW197435B (pt) 1990-11-22 1993-01-01 Takeda Pharm Industry Co Ltd
DE4111861A1 (de) 1991-04-11 1992-10-15 Schwabe Willmar Gmbh & Co Benzopyranone, verfahren zu ihrer herstellung und verwendung
JP2925363B2 (ja) 1991-07-09 1999-07-28 キヤノン株式会社 画像処理方法及び装置
DE4136288A1 (de) * 1991-11-04 1993-05-06 Troponwerke Gmbh & Co Kg, 5000 Koeln, De Kombination von calciumantagonisten mit cholinesterase-inhibitoren
JP3232830B2 (ja) 1993-11-30 2001-11-26 三菱電機株式会社 フレキシブルディスク装置のキャリッジ機構
DE69531877T2 (de) 1994-10-25 2004-07-29 Toyama Chemical Co. Ltd. Ein Wirkstoff für die Forderung von Nervwachstumfaktor Aktivität, der ein 1,2-Ethandiol-Derivat oder ein Salz davon enthält
US5889006A (en) 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
IL117149A0 (en) 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
WO1997030703A1 (fr) * 1996-02-20 1997-08-28 Toyama Chemical Co., Ltd. Agent ameliorant les fonctions cerebrales contenant des derives de 1,2-ethanediol ou des sels de celui-ci
WO1998001425A1 (en) * 1996-07-10 1998-01-15 Schering Corporation 1,4-di-sustituted piperidines as muscarinic antagonists
SK20199A3 (en) * 1996-08-15 2000-03-13 Schering Corp Ether muscarinic antagonists
JPH10259126A (ja) 1997-01-17 1998-09-29 Takeda Chem Ind Ltd アルツハイマー病治療・予防剤
US20030092737A1 (en) 1997-11-14 2003-05-15 Pierre Maffrand Jean Combination of active ingredients for the treatment of senile dementia of the Alzheimer type
CO4980891A1 (es) 1997-11-14 2000-11-27 Sanofi Sa Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer
WO1999031056A1 (fr) * 1997-12-12 1999-06-24 Toyama Chemical Co., Ltd. Derives d'ether alcoylique ou leurs sels, et antagonistes du calcium les contenant
HU229250B1 (en) 1999-06-11 2013-10-28 Toyama Chemical Co Ltd N-alkoxyalkyl-n,n-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same
BRPI0213393B8 (pt) 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
CN100375619C (zh) 2002-06-14 2008-03-19 富山化学工业株式会社 改善脑功能的药物组合物及其用途
CA2521648C (en) 2003-04-17 2012-07-03 Toyama Chemical Co., Ltd. Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
MX2008013728A (es) 2006-04-26 2009-01-07 Toyama Chemical Co Ltd Inductor de neurogenesis o agente terapeutico de neuropatia que abarca el derivado del eter alkilico o sal del mismo.
US8119625B2 (en) 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof

Also Published As

Publication number Publication date
DK1514542T3 (da) 2012-04-10
HUE041842T2 (hu) 2019-05-28
IL165589A (en) 2012-04-30
CY1112958T1 (el) 2016-04-13
NO20045158L (no) 2005-03-10
US20080103126A1 (en) 2008-05-01
PT1514542E (pt) 2012-03-27
KR100935615B1 (ko) 2010-01-07
AU2003236364A1 (en) 2003-12-31
SI2389937T1 (sl) 2018-10-30
AU2003236364B2 (en) 2008-08-21
PL217394B1 (pl) 2014-07-31
US7342043B2 (en) 2008-03-11
US7834053B2 (en) 2010-11-16
EP1514542B1 (en) 2012-02-22
MXPA04012534A (es) 2005-04-19
CN100375619C (zh) 2008-03-19
EP1514542A4 (en) 2009-06-03
KR20050010877A (ko) 2005-01-28
JPWO2003105830A1 (ja) 2005-10-13
TR201816386T4 (tr) 2018-11-21
ES2685923T3 (es) 2018-10-15
ZA200409901B (en) 2006-07-26
US20050250843A1 (en) 2005-11-10
BRPI0311780B1 (pt) 2017-09-26
EP2389937A1 (en) 2011-11-30
NO333504B1 (no) 2013-06-24
USRE42327E1 (en) 2011-05-03
AU2003236364C1 (en) 2009-12-24
CN1662232A (zh) 2005-08-31
CA2488120C (en) 2012-04-17
EP2389937B1 (en) 2018-08-15
JP4675103B2 (ja) 2011-04-20
NZ537090A (en) 2006-02-24
EP1514542A1 (en) 2005-03-16
DK2389937T3 (en) 2018-11-12
IL165589A0 (en) 2006-01-15
WO2003105830A1 (ja) 2003-12-24
SI1514542T1 (sl) 2012-06-29
ES2379948T3 (es) 2012-05-07
ATE546140T1 (de) 2012-03-15
CY1120591T1 (el) 2019-12-11
BR0311780A (pt) 2005-03-15
CA2488120A1 (en) 2003-12-24
PL372934A1 (en) 2005-08-08
BRPI0311780B8 (pt) 2021-05-25

Similar Documents

Publication Publication Date Title
CY1120591T1 (el) Ιατρικη συνθεση για βελτιωση λειτουργιας εγκεφαλου
PT1259489E (pt) Compostos azapoliciclicos condensados con arilo.
BG105365A (en) Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents
UA83899C2 (uk) Сполуки імідазолу для лікування нейродегенеративних розладів
CA2501799A1 (en) Pyrazole compounds for treatment of neurodegenerative disorders
MY140835A (en) Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
CA2534532A1 (en) Compounds for the treatment of neurodegenerative disorders
ATE119885T1 (de) 1,2,3,4-tetrahydro-9-akridinaminderivate.
TW200509933A (en) Therapeutic agents
WO2005095348A3 (en) Pyrazole-amine compounds for the treatment of neurodegenerative disorders
DE69822937D1 (de) Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen
ATE421961T1 (de) Piperidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung zur behandlung von alzheimer-krankheit, die diese derivate enthält
ZA891769B (en) Heterocyclic compounds
WO2005095361A8 (en) Isoxazole- and isothiazole-amine compounds for the treatment of neurodegenerative disorders
DK0950053T3 (da) Hidtil ukendte benzoylalkyl.1,2,3,6-tetrahydropyridinderivater