CY1120591T1 - Ιατρικη συνθεση για βελτιωση λειτουργιας εγκεφαλου - Google Patents

Ιατρικη συνθεση για βελτιωση λειτουργιας εγκεφαλου

Info

Publication number
CY1120591T1
CY1120591T1 CY181100871T CY181100871T CY1120591T1 CY 1120591 T1 CY1120591 T1 CY 1120591T1 CY 181100871 T CY181100871 T CY 181100871T CY 181100871 T CY181100871 T CY 181100871T CY 1120591 T1 CY1120591 T1 CY 1120591T1
Authority
CY
Cyprus
Prior art keywords
cerebral
ingredient
integer
optionally substituted
hydroxyl group
Prior art date
Application number
CY181100871T
Other languages
English (en)
Inventor
Yasushi Nakada
Masaya Nakagawa
Satoshi Ono
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of CY1120591T1 publication Critical patent/CY1120591T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Χρήση των παρακάτω συστατικών σε συνδυασμό για χρήση στη θεραπεία ή την αποτροπή δυσλειτουργίας εγκεφαλικών νευρώνων ακετυλοχολίνης στα επακόλουθα εγκεφαλοαγγειακής άνοιας, γεροντικής άνοιας, ασθένειας Alzheimer, ισχαιμικής εγκεφαλικής βλάβης και εγκεφαλικής αποπληξίας ή την εξασθένηση μνήμης που προκαλείται με εκλεκτικό νευρωνικό θάνατο:
CY181100871T 2002-06-14 2018-08-21 Ιατρικη συνθεση για βελτιωση λειτουργιας εγκεφαλου CY1120591T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002173483 2002-06-14
EP03760132A EP1514542B1 (en) 2002-06-14 2003-04-03 Medicinal composition comprising Tacrine or Donepezil for improving brain function.
PCT/JP2003/004292 WO2003105830A1 (ja) 2002-06-14 2003-04-03 脳機能を改善する医薬組成物および脳機能を改善するための方法

Publications (1)

Publication Number Publication Date
CY1120591T1 true CY1120591T1 (el) 2019-12-11

Family

ID=29727916

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20121100432T CY1112958T1 (el) 2002-06-14 2012-05-08 Ιατρικες συνθεσεις που περιλαμβανουν τακρινη ή ντονεπεζιλη για βελτιωση εγκεφαλικης λειτουργιας
CY181100871T CY1120591T1 (el) 2002-06-14 2018-08-21 Ιατρικη συνθεση για βελτιωση λειτουργιας εγκεφαλου

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20121100432T CY1112958T1 (el) 2002-06-14 2012-05-08 Ιατρικες συνθεσεις που περιλαμβανουν τακρινη ή ντονεπεζιλη για βελτιωση εγκεφαλικης λειτουργιας

Country Status (23)

Country Link
US (3) USRE42327E1 (el)
EP (2) EP1514542B1 (el)
JP (1) JP4675103B2 (el)
KR (1) KR100935615B1 (el)
CN (1) CN100375619C (el)
AT (1) ATE546140T1 (el)
AU (1) AU2003236364C1 (el)
BR (1) BRPI0311780B8 (el)
CA (1) CA2488120C (el)
CY (2) CY1112958T1 (el)
DK (2) DK2389937T3 (el)
ES (2) ES2685923T3 (el)
HU (1) HUE041842T2 (el)
IL (1) IL165589A (el)
MX (1) MXPA04012534A (el)
NO (1) NO333504B1 (el)
NZ (1) NZ537090A (el)
PL (1) PL217394B1 (el)
PT (2) PT1514542E (el)
SI (2) SI1514542T1 (el)
TR (1) TR201816386T4 (el)
WO (1) WO2003105830A1 (el)
ZA (1) ZA200409901B (el)

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KR20200024854A (ko) * 2017-07-08 2020-03-09 더 제너럴 하스피탈 코포레이션 알츠하이머 질환의 치료를 위한 치료 약물 또는 제제를 확인하기 위한 스크리닝 플랫폼
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KR20220040291A (ko) 2020-09-23 2022-03-30 씨엔지바이오 주식회사 4-메톡시-2-펜에틸이소인돌린-1-온 유도체 및 이를 포함하는 신경질환의 치료용 조성물

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DK1437353T3 (da) 2001-10-19 2007-08-06 Toyama Chemical Co Ltd Alkyletherderivater eller deres salte
DK2389937T3 (en) 2002-06-14 2018-11-12 Toyama Chemical Co Ltd Medical composition to improve brain function
US20060205709A1 (en) 2003-04-17 2006-09-14 Toyama Chemical Co., Ltd. Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
US20090093453A1 (en) 2006-04-26 2009-04-09 Toyama Chemical Co., Ltd Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
US8119625B2 (en) 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof

Also Published As

Publication number Publication date
DK2389937T3 (en) 2018-11-12
ES2685923T3 (es) 2018-10-15
US7342043B2 (en) 2008-03-11
CN100375619C (zh) 2008-03-19
USRE42327E1 (en) 2011-05-03
PT1514542E (pt) 2012-03-27
AU2003236364A1 (en) 2003-12-31
TR201816386T4 (tr) 2018-11-21
SI1514542T1 (sl) 2012-06-29
KR100935615B1 (ko) 2010-01-07
AU2003236364B2 (en) 2008-08-21
ES2379948T3 (es) 2012-05-07
PT2389937T (pt) 2018-10-26
KR20050010877A (ko) 2005-01-28
US20050250843A1 (en) 2005-11-10
BR0311780A (pt) 2005-03-15
PL372934A1 (en) 2005-08-08
CN1662232A (zh) 2005-08-31
EP1514542B1 (en) 2012-02-22
US20080103126A1 (en) 2008-05-01
HUE041842T2 (hu) 2019-05-28
US7834053B2 (en) 2010-11-16
JP4675103B2 (ja) 2011-04-20
NO333504B1 (no) 2013-06-24
ZA200409901B (en) 2006-07-26
JPWO2003105830A1 (ja) 2005-10-13
BRPI0311780B1 (pt) 2017-09-26
IL165589A (en) 2012-04-30
EP1514542A1 (en) 2005-03-16
DK1514542T3 (da) 2012-04-10
NO20045158L (no) 2005-03-10
NZ537090A (en) 2006-02-24
AU2003236364C1 (en) 2009-12-24
EP2389937B1 (en) 2018-08-15
BRPI0311780B8 (pt) 2021-05-25
CA2488120A1 (en) 2003-12-24
MXPA04012534A (es) 2005-04-19
CA2488120C (en) 2012-04-17
IL165589A0 (en) 2006-01-15
WO2003105830A1 (ja) 2003-12-24
EP2389937A1 (en) 2011-11-30
SI2389937T1 (sl) 2018-10-30
EP1514542A4 (en) 2009-06-03
CY1112958T1 (el) 2016-04-13
PL217394B1 (pl) 2014-07-31
ATE546140T1 (de) 2012-03-15

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