DK1514542T3 - Medicinsk sammensætning omfattende Tacrin eller Donepezil til forbedring af hjernefunktionen - Google Patents

Medicinsk sammensætning omfattende Tacrin eller Donepezil til forbedring af hjernefunktionen

Info

Publication number
DK1514542T3
DK1514542T3 DK03760132.5T DK03760132T DK1514542T3 DK 1514542 T3 DK1514542 T3 DK 1514542T3 DK 03760132 T DK03760132 T DK 03760132T DK 1514542 T3 DK1514542 T3 DK 1514542T3
Authority
DK
Denmark
Prior art keywords
donepezil
cerebral
ingredient
integer
tacrin
Prior art date
Application number
DK03760132.5T
Other languages
English (en)
Inventor
Yasushi Nakada
Masaya Nakagawa
Satoshi Ono
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK1514542T3 publication Critical patent/DK1514542T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
DK03760132.5T 2002-06-14 2003-04-03 Medicinsk sammensætning omfattende Tacrin eller Donepezil til forbedring af hjernefunktionen DK1514542T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002173483 2002-06-14
PCT/JP2003/004292 WO2003105830A1 (ja) 2002-06-14 2003-04-03 脳機能を改善する医薬組成物および脳機能を改善するための方法

Publications (1)

Publication Number Publication Date
DK1514542T3 true DK1514542T3 (da) 2012-04-10

Family

ID=29727916

Family Applications (2)

Application Number Title Priority Date Filing Date
DK11006318.7T DK2389937T3 (da) 2002-06-14 2003-04-03 Medicinsk sammensætning til forbedring af hjernefunktionen
DK03760132.5T DK1514542T3 (da) 2002-06-14 2003-04-03 Medicinsk sammensætning omfattende Tacrin eller Donepezil til forbedring af hjernefunktionen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK11006318.7T DK2389937T3 (da) 2002-06-14 2003-04-03 Medicinsk sammensætning til forbedring af hjernefunktionen

Country Status (23)

Country Link
US (3) US7342043B2 (da)
EP (2) EP2389937B1 (da)
JP (1) JP4675103B2 (da)
KR (1) KR100935615B1 (da)
CN (1) CN100375619C (da)
AT (1) ATE546140T1 (da)
AU (1) AU2003236364C1 (da)
BR (1) BRPI0311780B8 (da)
CA (1) CA2488120C (da)
CY (2) CY1112958T1 (da)
DK (2) DK2389937T3 (da)
ES (2) ES2379948T3 (da)
HU (1) HUE041842T2 (da)
IL (1) IL165589A (da)
MX (1) MXPA04012534A (da)
NO (1) NO333504B1 (da)
NZ (1) NZ537090A (da)
PL (1) PL217394B1 (da)
PT (2) PT2389937T (da)
SI (2) SI2389937T1 (da)
TR (1) TR201816386T4 (da)
WO (1) WO2003105830A1 (da)
ZA (1) ZA200409901B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL215264B1 (pl) * 2001-10-19 2013-11-29 Toyama Chemical Co Ltd Pochodne eteru alkilowego lub ich sole, sposób ich wytwarzania oraz kompozycja farmaceutyczna
SI2389937T1 (sl) 2002-06-14 2018-10-30 Toyama Chemical Co., Ltd, Farmacevtska sestava za izboljšanje možganske funkcije
KR101096528B1 (ko) * 2003-04-17 2011-12-20 토야마 케미칼 컴퍼니 리미티드 알킬에테르 유도체 또는 그 염을 함유하는 망막신경질환의예방·치료제
US7435837B2 (en) 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
EP2258359A3 (en) * 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US8119625B2 (en) * 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
WO2007125913A1 (ja) * 2006-04-26 2007-11-08 Toyama Chemical Co., Ltd. アルキルエーテル誘導体またはその塩を含有する神経細胞新生誘導剤および精神障害治療剤
JP5255441B2 (ja) * 2006-08-04 2013-08-07 富山化学工業株式会社 アルキルエーテル誘導体またはその塩を含有するプロテインキナーゼc活性促進剤
US20090221554A1 (en) * 2008-02-28 2009-09-03 Zenyaku Kogyo Kabushiki Kaisha Method of treating cognitive impairment
PT2287160E (pt) * 2008-05-28 2014-06-24 Toyama Chemical Co Ltd Derivado de óxido de benzotiofeno e os seus sais
EP2885267B1 (en) 2012-07-12 2018-09-05 Concert Pharmaceuticals, Inc. Deuterated idebenone
SG10201907035TA (en) * 2014-01-31 2019-09-27 Fujifilm Toyama Chemical Co Ltd Post nerve injury rehabilitation effect-enhancing agent comprising alkyl ether derivative or salt thereof
EP3636262A4 (en) 2017-06-02 2020-06-10 FUJIFILM Toyama Chemical Co., Ltd. AGENT FOR PREVENTING OR TREATING ALZHEIMER-LIKE DEMENTIA
BR112019024851A2 (pt) 2017-06-02 2020-06-09 Fujifilm Toyama Chemical Co Ltd agente para evitar ou tratar atrofia cerebral
IL270910B2 (en) 2017-06-02 2024-03-01 Fujifilm Toyama Chemical Co Ltd 1-(3-(2-(1-benzothiophene-5-yl)ethoxy)propyl)aztidine-3-ol or a salt thereof for use in suppressing cerebral atrophy
RU2019138538A (ru) 2017-06-02 2021-07-09 ФУДЖИФИЛМ Тояма Кемикал Ко., Лтд. СРЕДСТВО ДЛЯ УМЕНЬШЕНИЯ КОЛИЧЕСТВА АМИЛОИДНОГО β-БЕЛКА
KR20220101001A (ko) 2017-06-02 2022-07-18 후지필름 도야마 케미컬 가부시키가이샤 타우병증 예방 또는 치료제
SG11202000193UA (en) * 2017-07-08 2020-02-27 Massachusetts Gen Hospital Screening platform to identify therapeutic drugs or agents for treatment of alzheimer's disease
EP3705121B1 (en) 2017-10-30 2023-08-30 FUJIFILM Toyama Chemical Co., Ltd. Emopamil binding protein binding agent and use thereof
CN110464834B (zh) * 2019-09-04 2022-12-02 北京豪思生物科技股份有限公司 铜蓝蛋白联合多奈哌齐的应用
KR20220040291A (ko) 2020-09-23 2022-03-30 씨엔지바이오 주식회사 4-메톡시-2-펜에틸이소인돌린-1-온 유도체 및 이를 포함하는 신경질환의 치료용 조성물
KR20220040294A (ko) 2020-09-23 2022-03-30 씨엔지바이오 주식회사 6-메톡시-2-펜에틸이소인돌린-1-온 유도체 및 이를 포함하는 신경질환의 치료용 조성물

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74497A (en) 1985-03-05 1990-02-09 Proterra Ag Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives
US5177082A (en) 1985-11-05 1993-01-05 Yu Chao Mei Huperzines and analogs
US4663318A (en) 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
JPH0210827A (ja) 1988-06-29 1990-01-16 Matsushita Electron Corp 半導体装置の製造方法
NZ232493A (en) * 1989-02-14 1992-06-25 Toyama Chemical Co Ltd Aryl- or heterocyclyl-substituted 1,2-ethanediol derivatives and pharmaceutical compositions
US5280032A (en) 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
JP2887492B2 (ja) 1990-02-05 1999-04-26 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
JP2913196B2 (ja) 1989-04-26 1999-06-28 富山化学工業株式会社 1,2−エタンジオール誘導体またはその塩
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
JP3044055B2 (ja) * 1990-08-09 2000-05-22 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
JPH0676401B2 (ja) 1990-10-19 1994-09-28 エスエス製薬株式会社 キノリン誘導体及びこれを含有する医薬
TW197435B (da) 1990-11-22 1993-01-01 Takeda Pharm Industry Co Ltd
DE4111861A1 (de) 1991-04-11 1992-10-15 Schwabe Willmar Gmbh & Co Benzopyranone, verfahren zu ihrer herstellung und verwendung
JP2925363B2 (ja) 1991-07-09 1999-07-28 キヤノン株式会社 画像処理方法及び装置
DE4136288A1 (de) 1991-11-04 1993-05-06 Troponwerke Gmbh & Co Kg, 5000 Koeln, De Kombination von calciumantagonisten mit cholinesterase-inhibitoren
JP3232830B2 (ja) 1993-11-30 2001-11-26 三菱電機株式会社 フレキシブルディスク装置のキャリッジ機構
PL187004B1 (pl) 1994-10-25 2004-04-30 Toyama Chemical Co Ltd Nowe pochodne 1,2-etanodiolu oraz kompozycje farmaceutyczne je zawierające
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
WO1997030703A1 (fr) * 1996-02-20 1997-08-28 Toyama Chemical Co., Ltd. Agent ameliorant les fonctions cerebrales contenant des derives de 1,2-ethanediol ou des sels de celui-ci
NZ333513A (en) 1996-07-10 2000-04-28 Schering Corp 1,4-di-substituted piperidines and medicaments useful as muscarinic antagonists
PL331536A1 (en) * 1996-08-15 1999-07-19 Schering Corp Muscarinic antagonists with an etheric bond
JPH10259126A (ja) 1997-01-17 1998-09-29 Takeda Chem Ind Ltd アルツハイマー病治療・予防剤
US20030092737A1 (en) 1997-11-14 2003-05-15 Pierre Maffrand Jean Combination of active ingredients for the treatment of senile dementia of the Alzheimer type
CO4980891A1 (es) 1997-11-14 2000-11-27 Sanofi Sa Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer
AU1506499A (en) 1997-12-12 1999-07-05 Toyama Chemical Co. Ltd. Alkyl ether derivatives or salts thereof and calcium antagonists containing the same
KR100641352B1 (ko) * 1999-06-11 2006-11-02 토야마 케미칼 컴퍼니 리미티드 N-알콕시알킬-n,n-디알킬아민 유도체 또는 그 염, 및이를 함유하는 신경퇴행성질환 치료제
PL215264B1 (pl) 2001-10-19 2013-11-29 Toyama Chemical Co Ltd Pochodne eteru alkilowego lub ich sole, sposób ich wytwarzania oraz kompozycja farmaceutyczna
SI2389937T1 (sl) 2002-06-14 2018-10-30 Toyama Chemical Co., Ltd, Farmacevtska sestava za izboljšanje možganske funkcije
KR101096528B1 (ko) 2003-04-17 2011-12-20 토야마 케미칼 컴퍼니 리미티드 알킬에테르 유도체 또는 그 염을 함유하는 망막신경질환의예방·치료제
WO2007125913A1 (ja) 2006-04-26 2007-11-08 Toyama Chemical Co., Ltd. アルキルエーテル誘導体またはその塩を含有する神経細胞新生誘導剤および精神障害治療剤
US8119625B2 (en) 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof

Also Published As

Publication number Publication date
WO2003105830A1 (ja) 2003-12-24
IL165589A (en) 2012-04-30
JP4675103B2 (ja) 2011-04-20
SI1514542T1 (sl) 2012-06-29
AU2003236364A1 (en) 2003-12-31
BR0311780A (pt) 2005-03-15
PL217394B1 (pl) 2014-07-31
NO333504B1 (no) 2013-06-24
AU2003236364B2 (en) 2008-08-21
CA2488120C (en) 2012-04-17
US20080103126A1 (en) 2008-05-01
EP1514542B1 (en) 2012-02-22
CY1120591T1 (el) 2019-12-11
BRPI0311780B1 (pt) 2017-09-26
EP1514542A4 (en) 2009-06-03
ZA200409901B (en) 2006-07-26
CY1112958T1 (el) 2016-04-13
DK2389937T3 (da) 2018-11-12
TR201816386T4 (tr) 2018-11-21
HUE041842T2 (hu) 2019-05-28
KR100935615B1 (ko) 2010-01-07
SI2389937T1 (sl) 2018-10-30
PT1514542E (pt) 2012-03-27
CN100375619C (zh) 2008-03-19
JPWO2003105830A1 (ja) 2005-10-13
MXPA04012534A (es) 2005-04-19
CN1662232A (zh) 2005-08-31
AU2003236364C1 (en) 2009-12-24
BRPI0311780B8 (pt) 2021-05-25
CA2488120A1 (en) 2003-12-24
NO20045158L (no) 2005-03-10
USRE42327E1 (en) 2011-05-03
ATE546140T1 (de) 2012-03-15
EP2389937A1 (en) 2011-11-30
PL372934A1 (en) 2005-08-08
US7342043B2 (en) 2008-03-11
US7834053B2 (en) 2010-11-16
NZ537090A (en) 2006-02-24
ES2685923T3 (es) 2018-10-15
ES2379948T3 (es) 2012-05-07
US20050250843A1 (en) 2005-11-10
IL165589A0 (en) 2006-01-15
KR20050010877A (ko) 2005-01-28
EP2389937B1 (en) 2018-08-15
PT2389937T (pt) 2018-10-26
EP1514542A1 (en) 2005-03-16

Similar Documents

Publication Publication Date Title
CY1120591T1 (el) Ιατρικη συνθεση για βελτιωση λειτουργιας εγκεφαλου
PT1259489E (pt) Compostos azapoliciclicos condensados con arilo.
ATE361287T1 (de) Neue indol-2-on derivate
TR199900255T2 (xx) Muskarinik antagonistleri
EA200601192A1 (ru) ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ 8'-ПИРИ(МИ)ДИНИЛДИГИДРОСПИРО[ЦИКЛОАЛКИЛАМИН]ПИРИМИДО[1,2-a]ПИРИМИДИН-6-ОНА
SG161217A1 (en) New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-alzheimer agents
EP1201239A4 (en) CYCLIC AMINES AS CCR3 ANTAGONISTS
MY140835A (en) Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
NO20073760L (no) Triazolon-, tetrazolon- og imidazolonderivater for anvendelse som alfa-2C-adrenoreseptorantagonister
NO940163D0 (no) Tricyklisk kondenserte heterocykliske forbindelser, deres fremstilling og anvendelse
CA2534532A1 (en) Compounds for the treatment of neurodegenerative disorders
NO20075477L (no) Tetrahydro-pyridoazepin-8-one og beslektede forbindelser for behandling av schizofreni
ATE401082T1 (de) Medizinische zusammensetzung zur prävention oder behandlung von zerebrovaskulären störungen
WO2005095348A3 (en) Pyrazole-amine compounds for the treatment of neurodegenerative disorders
ATE420853T1 (de) 5-amidino-2-hydroxybenzolsulfonamidderivate, pharmazeutischen zusammensetzungen, die diese verbindungen enthalten, und zwischenprodukte zu deren herstellung
WO2005097114A3 (en) Thiazole sulfonamide compounds for the treatment of neurodegenerative disorders
DE60139409D1 (de) Pharmazeutische zusammensetzungen die ein dibenzocyclooctanlignanderivat enthalten zur vorbeugung und behandlung neurodegenerativer erkrankungen
DE60231054D1 (de) Piperidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung zur behandlung von alzheimer-krankheit, die diese derivate enthält
MX9300203A (es) Compuestos policiclicos disubstituidos y composicion farmaceutica que los contiene.
ATE263769T1 (de) Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen
ATE334680T1 (de) 4-aminopiperidin-derivate, verfahren zur herstellung und ihre verwendung als arzneimittel
NO891071L (no) Fremgangsmaate for fremstilling av 4,5,6,7-tetrahydro-isotiazolo(4,5-c)-pyridinderivater og isomere.
DE69724418D1 (de) Heterocyclische verbindungen und ihre herstellung und verwendung
ATE423093T1 (de) Neue mao-b-hemmer
DE60233715D1 (de) Mittel zur behandlung des haares