PT1971601E - Derivados de n4-fenil-quinazolina-4-amina e compostos relacionados como inibidores de tirosina quinases receptoras do tipo i erbb para o tratamento de doenças hiperproliferativas - Google Patents

Derivados de n4-fenil-quinazolina-4-amina e compostos relacionados como inibidores de tirosina quinases receptoras do tipo i erbb para o tratamento de doenças hiperproliferativas Download PDF

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Publication number
PT1971601E
PT1971601E PT06837728T PT06837728T PT1971601E PT 1971601 E PT1971601 E PT 1971601E PT 06837728 T PT06837728 T PT 06837728T PT 06837728 T PT06837728 T PT 06837728T PT 1971601 E PT1971601 E PT 1971601E
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Portugal
Prior art keywords
treatment
type
tyrosine kinase
kinase inhibitors
quinazoline
Prior art date
Application number
PT06837728T
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English (en)
Portuguese (pt)
Inventor
Joseph P Lyssikatos
Fredrik P Marmsater
Qian Zhao
Julie Marie Greschuk
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Array Biopharma Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38022019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1971601(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of PT1971601E publication Critical patent/PT1971601E/pt

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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • C07—ORGANIC CHEMISTRY
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Diabetes (AREA)
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  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
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PT06837728T 2005-11-15 2006-11-15 Derivados de n4-fenil-quinazolina-4-amina e compostos relacionados como inibidores de tirosina quinases receptoras do tipo i erbb para o tratamento de doenças hiperproliferativas PT1971601E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73628905P 2005-11-15 2005-11-15
US81701906P 2006-06-28 2006-06-28

Publications (1)

Publication Number Publication Date
PT1971601E true PT1971601E (pt) 2010-01-26

Family

ID=38022019

Family Applications (2)

Application Number Title Priority Date Filing Date
PT06837728T PT1971601E (pt) 2005-11-15 2006-11-15 Derivados de n4-fenil-quinazolina-4-amina e compostos relacionados como inibidores de tirosina quinases receptoras do tipo i erbb para o tratamento de doenças hiperproliferativas
PT09157031T PT2090575E (pt) 2005-11-15 2006-11-15 Inibidores de erbb

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT09157031T PT2090575E (pt) 2005-11-15 2006-11-15 Inibidores de erbb

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Country Link
US (6) US8648087B2 (enExample)
EP (2) EP1971601B1 (enExample)
JP (2) JP5134548B2 (enExample)
KR (1) KR101086967B1 (enExample)
CN (2) CN102887891B (enExample)
AT (2) ATE446294T1 (enExample)
AU (2) AU2006315383B2 (enExample)
BE (1) BE2021C531I2 (enExample)
BR (2) BRPI0618668B1 (enExample)
CA (2) CA2755268C (enExample)
CY (3) CY1110583T1 (enExample)
DE (2) DE602006009968D1 (enExample)
DK (2) DK1971601T3 (enExample)
ES (2) ES2364901T3 (enExample)
FI (1) FIC20210022I1 (enExample)
FR (1) FR21C1031I2 (enExample)
HU (1) HUS2100028I1 (enExample)
IL (2) IL239149A (enExample)
LT (1) LTC1971601I2 (enExample)
LU (1) LUC00217I2 (enExample)
NL (1) NL301113I2 (enExample)
NO (1) NO342413B1 (enExample)
PL (2) PL1971601T3 (enExample)
PT (2) PT1971601E (enExample)
RU (2) RU2592703C9 (enExample)
SG (1) SG152230A1 (enExample)
SI (2) SI1971601T1 (enExample)
WO (1) WO2007059257A2 (enExample)
ZA (1) ZA200804498B (enExample)

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US7501427B2 (en) * 2003-08-14 2009-03-10 Array Biopharma, Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
EP1971601B1 (en) 2005-11-15 2009-10-21 Array Biopharma Inc. N4-phenyl-quinazoline-4 -amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
KR20090067169A (ko) * 2006-09-11 2009-06-24 쿠리스 인코퍼레이션 아연 결합 부분을 함유한 퀴나졸린 계열 ｅｇｆｒ 억제제
WO2008033747A2 (en) * 2006-09-11 2008-03-20 Curis, Inc. Multi-functional small molecules as anti-proliferative agents
US7547781B2 (en) 2006-09-11 2009-06-16 Curis, Inc. Quinazoline based EGFR inhibitors containing a zinc binding moiety
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
US8304557B2 (en) * 2007-06-05 2012-11-06 Takeda Pharmaceutical Company Limited Fused heterocycle derivatives and use thereof
CN101801951B (zh) 2007-09-14 2013-11-13 杨森制药有限公司 1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮
WO2009033703A1 (en) 2007-09-14 2009-03-19 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones
WO2009033702A1 (en) 2007-09-14 2009-03-19 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
MX2010005110A (es) 2007-11-14 2010-09-09 Ortho Mcneil Janssen Pharm Derivados de imidazo[1,2-a]piridina y su uso como moduladores alostericos positivos de los receptores de glutamato metabotropico 2.
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WO2007059257A3 (en) 2007-08-23
US9693989B2 (en) 2017-07-04
FIC20210022I1 (fi) 2021-07-09
DE602006009968D1 (de) 2009-12-03
JP2010270154A (ja) 2010-12-02
US12171739B2 (en) 2024-12-24
IL248993A0 (en) 2017-01-31
US10780073B2 (en) 2020-09-22
AU2010202330A1 (en) 2010-07-01
US20110034689A1 (en) 2011-02-10
BE2021C531I2 (enExample) 2026-02-02
IL239149A (en) 2016-11-30
RU2008118417A (ru) 2009-12-27
DK2090575T3 (da) 2011-05-23
CA2755268A1 (en) 2007-05-24
HK1119174A1 (en) 2009-02-27
CN102887891A (zh) 2013-01-23
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HUS2100028I1 (hu) 2021-08-30
ATE507224T1 (de) 2011-05-15

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