JP5134548B2 - 過剰増殖性疾患の処置のためのＥｒｂＢＩ型受容体チロシンキナーゼ阻害剤としてのＮ４−フェニルキナゾリン−４−アミン誘導体および関連化合物 - Google Patents

過剰増殖性疾患の処置のためのＥｒｂＢＩ型受容体チロシンキナーゼ阻害剤としてのＮ４−フェニルキナゾリン−４−アミン誘導体および関連化合物 Download PDF

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JP5134548B2
JP5134548B2 JP2008541330A JP2008541330A JP5134548B2 JP 5134548 B2 JP5134548 B2 JP 5134548B2 JP 2008541330 A JP2008541330 A JP 2008541330A JP 2008541330 A JP2008541330 A JP 2008541330A JP 5134548 B2 JP5134548 B2 JP 5134548B2
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alkyl
saturated
partially unsaturated
heterocyclyl
heteroaryl
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リーシイカトーズ，ジョセフ・ピィ
マーマセーテル，フレドリック・ピィ
チャオ，チアン
グレシューク，ジュリー・マリー
リュウ，ウェイトン
ヘニングズ，ディ・デイビッド
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アレイ バイオファーマ、インコーポレイテッド
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JP2008541330A 2005-11-15 2006-11-15 過剰増殖性疾患の処置のためのＥｒｂＢＩ型受容体チロシンキナーゼ阻害剤としてのＮ４−フェニルキナゾリン−４−アミン誘導体および関連化合物 Active JP5134548B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73628905P 2005-11-15 2005-11-15
US60/736,289 2005-11-15
US81701906P 2006-06-28 2006-06-28
US60/817,019 2006-06-28
PCT/US2006/044431 WO2007059257A2 (en) 2005-11-15 2006-11-15 N4-phenyl-quinaz0line-4 -amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases

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JP2010198848A Division JP5232841B2 (ja) 2005-11-15 2010-09-06 Ｎ４−フェニルキナゾリン−４−アミン誘導体の製造方法およびその中間体

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JP2009515988A JP2009515988A (ja) 2009-04-16
JP2009515988A5 JP2009515988A5 (enExample) 2010-10-21
JP5134548B2 true JP5134548B2 (ja) 2013-01-30

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JP2008541330A Active JP5134548B2 (ja) 2005-11-15 2006-11-15 過剰増殖性疾患の処置のためのＥｒｂＢＩ型受容体チロシンキナーゼ阻害剤としてのＮ４−フェニルキナゾリン−４−アミン誘導体および関連化合物
JP2010198848A Active JP5232841B2 (ja) 2005-11-15 2010-09-06 Ｎ４−フェニルキナゾリン−４−アミン誘導体の製造方法およびその中間体

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WO2005016346A1 (en) 2003-08-14 2005-02-24 Array Biopharma Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
US7501427B2 (en) 2003-08-14 2009-03-10 Array Biopharma, Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
PT2090575E (pt) 2005-11-15 2011-06-06 Array Biopharma Inc Inibidores de erbb
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HK1129678A1 (en) 2009-12-04
SG152230A1 (en) 2009-05-29
IL248993B (en) 2018-11-29
EP1971601B1 (en) 2009-10-21
JP2009515988A (ja) 2009-04-16
CN102887891A (zh) 2013-01-23
CA2632194A1 (en) 2007-05-24
RU2011122539A (ru) 2012-12-10
IL239149A0 (en) 2015-07-30
PL2090575T3 (pl) 2011-09-30
KR20080070064A (ko) 2008-07-29
CY1112754T1 (el) 2016-02-10
US9693989B2 (en) 2017-07-04
BR122018075851B1 (pt) 2022-01-11
RU2592703C9 (ru) 2016-10-20
PL1971601T3 (pl) 2010-03-31
FIC20210022I1 (fi) 2021-07-09
ATE446294T1 (de) 2009-11-15
CN102887891B (zh) 2016-03-09
AU2006315383B2 (en) 2011-06-02
ZA200804498B (en) 2009-07-29
RU2592703C2 (ru) 2016-07-27
AU2010202330A1 (en) 2010-07-01
SI2090575T1 (sl) 2011-08-31
AU2010202330B2 (en) 2012-07-19
PT2090575E (pt) 2011-06-06
NO20082598L (no) 2008-08-06
WO2007059257A3 (en) 2007-08-23
DK1971601T3 (da) 2010-02-08
AU2006315383A1 (en) 2007-05-24
EP2090575B1 (en) 2011-04-27
JP5232841B2 (ja) 2013-07-10
LTPA2021516I1 (enExample) 2021-08-10
CY2021019I1 (el) 2021-10-15
IL239149A (en) 2016-11-30
RU2008118417A (ru) 2009-12-27
SI1971601T1 (sl) 2010-03-31
EP2090575A1 (en) 2009-08-19
US20210008023A1 (en) 2021-01-14
US20140023643A1 (en) 2014-01-23
WO2007059257A2 (en) 2007-05-24
HUS2100028I1 (hu) 2021-08-30
IL248993A0 (en) 2017-01-31
CY1110583T1 (el) 2015-04-29
DE602006009968D1 (de) 2009-12-03
JP2010270154A (ja) 2010-12-02
FR21C1031I2 (fr) 2022-07-15
HK1119174A1 (en) 2009-02-27
NL301113I1 (nl) 2021-07-01
LTC1971601I2 (enExample) 2022-10-25
NO342413B1 (no) 2018-05-22
US12171739B2 (en) 2024-12-24
RU2428421C2 (ru) 2011-09-10
US20180271824A1 (en) 2018-09-27
CA2632194C (en) 2012-01-03
DK2090575T3 (da) 2011-05-23
ATE507224T1 (de) 2011-05-15
US20230142839A1 (en) 2023-05-11
LUC00217I2 (enExample) 2022-10-07
NL301113I2 (nl) 2021-08-03
ES2364901T3 (es) 2011-09-16
CY2021019I2 (el) 2021-12-31
CA2755268A1 (en) 2007-05-24

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