ZA200804498B - N4-phenyl-quinazoline-4 -amine derivatives and related compounds as ERBB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases - Google Patents

N4-phenyl-quinazoline-4 -amine derivatives and related compounds as ERBB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases

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Publication number
ZA200804498B
ZA200804498B ZA200804498A ZA200804498A ZA200804498B ZA 200804498 B ZA200804498 B ZA 200804498B ZA 200804498 A ZA200804498 A ZA 200804498A ZA 200804498 A ZA200804498 A ZA 200804498A ZA 200804498 B ZA200804498 B ZA 200804498B
Authority
ZA
South Africa
Prior art keywords
treatment
tyrosine kinase
kinase inhibitors
quinazoline
receptor tyrosine
Prior art date
Application number
ZA200804498A
Other languages
English (en)
Inventor
Joseph P Lyssikatos
Fredrik P Marmsater
Zhao Qian
Greschuk Julie Marie
Liu Weidong
Hennings D David
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38022019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200804498(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of ZA200804498B publication Critical patent/ZA200804498B/xx

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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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ZA200804498A 2005-11-15 2006-11-15 N4-phenyl-quinazoline-4 -amine derivatives and related compounds as ERBB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases ZA200804498B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73628905P 2005-11-15 2005-11-15
US81701906P 2006-06-28 2006-06-28

Publications (1)

Publication Number Publication Date
ZA200804498B true ZA200804498B (en) 2009-07-29

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ZA200804498A ZA200804498B (en) 2005-11-15 2006-11-15 N4-phenyl-quinazoline-4 -amine derivatives and related compounds as ERBB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases

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US (6) US8648087B2 (enExample)
EP (2) EP1971601B1 (enExample)
JP (2) JP5134548B2 (enExample)
KR (1) KR101086967B1 (enExample)
CN (2) CN102887891B (enExample)
AT (2) ATE507224T1 (enExample)
AU (2) AU2006315383B2 (enExample)
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AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
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SG174772A1 (en) * 2006-09-11 2011-10-28 Curis Inc Multi-functional small molecules as anti-proliferative agents
CA2662617C (en) * 2006-09-11 2014-11-18 Changgeng Qian Quinazoline based egfr inhibitors containing a zinc binding moiety
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
JP5352476B2 (ja) * 2007-06-05 2013-11-27 武田薬品工業株式会社 キナーゼ阻害剤としての二環式複素環化合物
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JP5547194B2 (ja) 2008-09-02 2014-07-09 ジャンセン ファーマシューティカルズ， インコーポレイテッド． 代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体
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EP2090575A1 (en) 2009-08-19
AU2010202330B2 (en) 2012-07-19
JP5232841B2 (ja) 2013-07-10
CY1110583T1 (el) 2015-04-29
NL301113I1 (nl) 2021-07-01
US20140023643A1 (en) 2014-01-23
BRPI0618668A2 (pt) 2011-09-06
JP2009515988A (ja) 2009-04-16
IL239149A0 (en) 2015-07-30
NO20082598L (no) 2008-08-06
CY2021019I2 (el) 2021-12-31
FR21C1031I1 (enExample) 2021-08-27
FR21C1031I2 (fr) 2022-07-15
PT1971601E (pt) 2010-01-26
ATE446294T1 (de) 2009-11-15
BR122018075851B1 (pt) 2022-01-11
BRPI0618668B1 (pt) 2021-09-21
DE602006021645D1 (de) 2011-06-09
DK2090575T3 (da) 2011-05-23
AU2010202330A1 (en) 2010-07-01
IL248993A0 (en) 2017-01-31
KR20080070064A (ko) 2008-07-29
PL2090575T3 (pl) 2011-09-30
WO2007059257A8 (en) 2008-06-19

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