ATE507224T1 - Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten - Google Patents

Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten

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Publication number
ATE507224T1
ATE507224T1 AT09157031T AT09157031T ATE507224T1 AT E507224 T1 ATE507224 T1 AT E507224T1 AT 09157031 T AT09157031 T AT 09157031T AT 09157031 T AT09157031 T AT 09157031T AT E507224 T1 ATE507224 T1 AT E507224T1
Authority
AT
Austria
Prior art keywords
quinazoline
phenyl
producing
intermediate compounds
amine derivatives
Prior art date
Application number
AT09157031T
Other languages
German (de)
English (en)
Inventor
Joseph Lyssikatos
Julie Greschuk
Qian Zhao
Fredrik Marmsaeter
Weidong Lui
David D Hennings
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38022019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE507224(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Application granted granted Critical
Publication of ATE507224T1 publication Critical patent/ATE507224T1/de

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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • C07—ORGANIC CHEMISTRY
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Communicable Diseases (AREA)
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  • Hematology (AREA)
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AT09157031T 2005-11-15 2006-11-15 Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten ATE507224T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73628905P 2005-11-15 2005-11-15
US81701906P 2006-06-28 2006-06-28

Publications (1)

Publication Number Publication Date
ATE507224T1 true ATE507224T1 (de) 2011-05-15

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ID=38022019

Family Applications (2)

Application Number Title Priority Date Filing Date
AT09157031T ATE507224T1 (de) 2005-11-15 2006-11-15 Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten
AT06837728T ATE446294T1 (de) 2005-11-15 2006-11-15 N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06837728T ATE446294T1 (de) 2005-11-15 2006-11-15 N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten

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US (6) US8648087B2 (enExample)
EP (2) EP2090575B1 (enExample)
JP (2) JP5134548B2 (enExample)
KR (1) KR101086967B1 (enExample)
CN (2) CN102887891B (enExample)
AT (2) ATE507224T1 (enExample)
AU (2) AU2006315383B2 (enExample)
BR (2) BR122018075851B1 (enExample)
CA (2) CA2632194C (enExample)
CY (3) CY1110583T1 (enExample)
DE (2) DE602006021645D1 (enExample)
DK (2) DK2090575T3 (enExample)
ES (2) ES2364901T3 (enExample)
FI (1) FIC20210022I1 (enExample)
FR (1) FR21C1031I2 (enExample)
HU (1) HUS2100028I1 (enExample)
IL (2) IL239149A (enExample)
LT (1) LTC1971601I2 (enExample)
LU (1) LUC00217I2 (enExample)
NL (1) NL301113I2 (enExample)
NO (1) NO342413B1 (enExample)
PL (2) PL2090575T3 (enExample)
PT (2) PT2090575E (enExample)
RU (2) RU2592703C9 (enExample)
SG (1) SG152230A1 (enExample)
SI (2) SI1971601T1 (enExample)
WO (1) WO2007059257A2 (enExample)
ZA (1) ZA200804498B (enExample)

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ES2364901T3 (es) 2005-11-15 2011-09-16 Array Biopharma, Inc. Procesos e intermedios para la preparación de derivados de n4-fenil-quinazolin-4-amina.
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
SG174774A1 (en) * 2006-09-11 2011-10-28 Curis Inc Quinazoline based egfr inhibitors containing a zinc binding moiety
JP2010502743A (ja) * 2006-09-11 2010-01-28 キュリス，インコーポレイテッド 抗増殖薬剤としての多機能性低分子
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TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
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CN101848893B (zh) 2007-09-14 2012-06-06 奥梅-杨森制药有限公司 1,3-二取代的4-(芳基-x-苯基)-1h-吡啶-2-酮
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TWI445532B (zh) 2007-09-14 2014-07-21 Janssen Pharmaceuticals Inc １’，３’－二取代－４－苯基－３，４，５，６－四氫－２ｈ，１’ｈ－〔１，４’〕聯吡啶基－２’－酮化物
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HUS2100028I1 (hu) 2021-08-30
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NL301113I2 (nl) 2021-08-03
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RU2592703C9 (ru) 2016-10-20
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CN102887891B (zh) 2016-03-09
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IL248993B (en) 2018-11-29
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US20180271824A1 (en) 2018-09-27
BRPI0618668B1 (pt) 2021-09-21
PL1971601T3 (pl) 2010-03-31
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US9693989B2 (en) 2017-07-04
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IL239149A (en) 2016-11-30
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