PT1497293E - Derivados de [1,4]diazepino[6,7,1-ij]quinolina como agentes antipsicóticos e antiobesidade - Google Patents

Derivados de [1,4]diazepino[6,7,1-ij]quinolina como agentes antipsicóticos e antiobesidade Download PDF

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Publication number
PT1497293E
PT1497293E PT03728523T PT03728523T PT1497293E PT 1497293 E PT1497293 E PT 1497293E PT 03728523 T PT03728523 T PT 03728523T PT 03728523 T PT03728523 T PT 03728523T PT 1497293 E PT1497293 E PT 1497293E
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PT
Portugal
Prior art keywords
diazepino
quinoline derivatives
antiobesity agents
anti psychotic
psychotic
Prior art date
Application number
PT03728523T
Other languages
English (en)
Inventor
Sivaramakrishnan P Ramamoorthy
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PT1497293E publication Critical patent/PT1497293E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT03728523T 2002-04-25 2003-04-24 Derivados de [1,4]diazepino[6,7,1-ij]quinolina como agentes antipsicóticos e antiobesidade PT1497293E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37559202P 2002-04-25 2002-04-25

Publications (1)

Publication Number Publication Date
PT1497293E true PT1497293E (pt) 2008-09-05

Family

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PT03728523T PT1497293E (pt) 2002-04-25 2003-04-24 Derivados de [1,4]diazepino[6,7,1-ij]quinolina como agentes antipsicóticos e antiobesidade

Country Status (28)

Country Link
US (2) US7129237B2 (pt)
EP (1) EP1497293B1 (pt)
JP (1) JP4537075B2 (pt)
KR (1) KR101009269B1 (pt)
CN (2) CN1955179B (pt)
AR (1) AR039669A1 (pt)
AT (1) ATE398127T1 (pt)
AU (1) AU2003234213C1 (pt)
BR (1) BR0309664A (pt)
CA (1) CA2481321C (pt)
CR (1) CR7510A (pt)
CY (1) CY1108286T1 (pt)
DE (1) DE60321559D1 (pt)
DK (1) DK1497293T3 (pt)
EC (1) ECSP045379A (pt)
ES (1) ES2307937T3 (pt)
HK (1) HK1069388A1 (pt)
IL (1) IL164806A0 (pt)
MX (1) MXPA04010372A (pt)
NO (1) NO329505B1 (pt)
NZ (1) NZ536115A (pt)
PT (1) PT1497293E (pt)
RU (1) RU2312866C2 (pt)
SI (1) SI1497293T1 (pt)
TW (1) TWI312781B (pt)
UA (1) UA79782C2 (pt)
WO (1) WO2003091250A1 (pt)
ZA (1) ZA200409501B (pt)

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Publication number Publication date
CY1108286T1 (el) 2014-02-12
KR101009269B1 (ko) 2011-01-18
KR20050000405A (ko) 2005-01-03
ES2307937T3 (es) 2008-12-01
RU2004134361A (ru) 2005-05-10
CN1955179A (zh) 2007-05-02
JP2005529893A (ja) 2005-10-06
RU2312866C2 (ru) 2007-12-20
AU2003234213B2 (en) 2009-11-12
JP4537075B2 (ja) 2010-09-01
ECSP045379A (es) 2004-11-26
TWI312781B (en) 2009-08-01
SI1497293T1 (sl) 2008-10-31
EP1497293A1 (en) 2005-01-19
CA2481321C (en) 2012-01-03
AU2003234213A1 (en) 2003-11-10
ATE398127T1 (de) 2008-07-15
WO2003091250A1 (en) 2003-11-06
US20040009970A1 (en) 2004-01-15
IL164806A0 (en) 2005-12-18
CR7510A (es) 2008-07-29
NZ536115A (en) 2007-11-30
DK1497293T3 (da) 2008-09-15
NO20044501L (no) 2005-01-18
CN1955179B (zh) 2010-07-14
US7129237B2 (en) 2006-10-31
ZA200409501B (en) 2007-04-25
AU2003234213C1 (en) 2010-05-20
NO329505B1 (no) 2010-11-01
AR039669A1 (es) 2005-03-02
HK1069388A1 (en) 2005-05-20
BR0309664A (pt) 2005-02-22
CN100376575C (zh) 2008-03-26
UA79782C2 (en) 2007-07-25
DE60321559D1 (de) 2008-07-24
CN1662533A (zh) 2005-08-31
US7687620B2 (en) 2010-03-30
US20070004707A1 (en) 2007-01-04
CA2481321A1 (en) 2003-11-06
EP1497293B1 (en) 2008-06-11
MXPA04010372A (es) 2005-02-03
TW200400038A (en) 2004-01-01

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