AU2003240742A1 - 4,5-dihydro-imidazo (4,5,1-ij) quinolin-6-ones derivatives and their use as poly (adp-ribosyl) transferase (parp) inhibitors - Google Patents

4,5-dihydro-imidazo (4,5,1-ij) quinolin-6-ones derivatives and their use as poly (adp-ribosyl) transferase (parp) inhibitors

Info

Publication number
AU2003240742A1
AU2003240742A1 AU2003240742A AU2003240742A AU2003240742A1 AU 2003240742 A1 AU2003240742 A1 AU 2003240742A1 AU 2003240742 A AU2003240742 A AU 2003240742A AU 2003240742 A AU2003240742 A AU 2003240742A AU 2003240742 A1 AU2003240742 A1 AU 2003240742A1
Authority
AU
Australia
Prior art keywords
ribosyl
parp
quinolin
adp
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003240742A
Inventor
Rainer Boer
Frank Dullweber
Thomas Klein
Thomas Wagner
Steffen Weinbrenner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Publication of AU2003240742A1 publication Critical patent/AU2003240742A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2003240742A 2002-06-07 2003-06-04 4,5-dihydro-imidazo (4,5,1-ij) quinolin-6-ones derivatives and their use as poly (adp-ribosyl) transferase (parp) inhibitors Abandoned AU2003240742A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02012704 2002-06-07
EP02012704.9 2002-06-07
PCT/EP2003/005834 WO2003104233A1 (en) 2002-06-07 2003-06-04 4,5-dihydro-imidazo (4,5,1-ij) quinolin-6-ones derivatives and their use as poly (adp-ribosyl) transferase (parp) inhibitors

Publications (1)

Publication Number Publication Date
AU2003240742A1 true AU2003240742A1 (en) 2003-12-22

Family

ID=29724381

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003240742A Abandoned AU2003240742A1 (en) 2002-06-07 2003-06-04 4,5-dihydro-imidazo (4,5,1-ij) quinolin-6-ones derivatives and their use as poly (adp-ribosyl) transferase (parp) inhibitors

Country Status (2)

Country Link
AU (1) AU2003240742A1 (en)
WO (1) WO2003104233A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2497903A1 (en) * 2002-09-18 2004-04-01 Ono Pharmaceutical Co., Ltd. Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient
DE102005012875B4 (en) 2005-03-19 2006-11-16 Sanofi-Aventis Deutschland Gmbh Use of amino-substituted 8-N-benzimidazoles
DE102005012874A1 (en) 2005-03-19 2006-09-21 Sanofi-Aventis Deutschland Gmbh Amide-substituted 8-N-benzimidazoles, process for their preparation and their use as pharmaceuticals
TW200804382A (en) 2005-12-05 2008-01-16 Incyte Corp Lactam compounds and methods of using the same
US8273900B2 (en) 2008-08-07 2012-09-25 Novartis Ag Organic compounds
GB201220157D0 (en) * 2012-11-08 2012-12-26 Selvita Sa Substitute tricyclic benzimidazoles as kinase inhibitors
CN111349094B (en) * 2020-04-23 2021-02-02 杭州师范大学 6H-imidazo [4,5,1-ij ] quinolone and synthesis method and application thereof
WO2022226166A1 (en) * 2021-04-22 2022-10-27 Protego Biopharma, Inc. Spirocyclic imidazolidinones and imidazolidinediones for treatment of light chain amyloidosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710915B1 (en) * 1993-10-04 1995-11-24 Synthelabo Piperidine derivatives, their preparation and their therapeutic use.
DE10039610A1 (en) * 2000-08-09 2002-02-28 Basf Ag Azepinoindole derivatives are PARP inhibitors and are useful for the treatment of neurodegenerative diseases, ischemia, tumor, septic shock, inflammation, rheumatic diseases, ARDS and diabetes mellitus
AR030121A1 (en) * 2000-08-08 2003-08-13 Sanofi Aventis DERIVATIVES OF BENZIMIDAZOL, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS

Also Published As

Publication number Publication date
WO2003104233A1 (en) 2003-12-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase