PT1341526E - Composições farmacêuticas para a administração oral de calcitonina - Google Patents

Composições farmacêuticas para a administração oral de calcitonina Download PDF

Info

Publication number
PT1341526E
PT1341526E PT01985368T PT01985368T PT1341526E PT 1341526 E PT1341526 E PT 1341526E PT 01985368 T PT01985368 T PT 01985368T PT 01985368 T PT01985368 T PT 01985368T PT 1341526 E PT1341526 E PT 1341526E
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
calcitonin
pharmacologically active
oral delivery
delivery
Prior art date
Application number
PT01985368T
Other languages
English (en)
Inventor
Simon David Bateman
Joseph M Ault
Moise Azria
Joseph Sikora
Gregory Sparta
Rebecca Fai-Ying Yang
Jie Xiao
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1341526E publication Critical patent/PT1341526E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT01985368T 2000-12-06 2001-12-05 Composições farmacêuticas para a administração oral de calcitonina PT1341526E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25172900P 2000-12-06 2000-12-06

Publications (1)

Publication Number Publication Date
PT1341526E true PT1341526E (pt) 2011-09-01

Family

ID=22953160

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01985368T PT1341526E (pt) 2000-12-06 2001-12-05 Composições farmacêuticas para a administração oral de calcitonina

Country Status (27)

Country Link
US (1) US7049283B2 (pt)
EP (1) EP1341526B1 (pt)
JP (2) JP4898078B2 (pt)
KR (1) KR100847695B1 (pt)
CN (1) CN1304048C (pt)
AT (1) ATE513541T1 (pt)
AU (2) AU2002234547B2 (pt)
BR (2) BR0115965A (pt)
CA (1) CA2436599C (pt)
CY (1) CY1112562T1 (pt)
CZ (1) CZ305418B6 (pt)
DK (1) DK1341526T3 (pt)
EC (1) ECSP034639A (pt)
ES (1) ES2367009T3 (pt)
HK (1) HK1059565A1 (pt)
HU (1) HU230632B1 (pt)
IL (2) IL155992A0 (pt)
MX (1) MXPA03005096A (pt)
NO (1) NO332936B1 (pt)
NZ (1) NZ526196A (pt)
PL (1) PL209703B1 (pt)
PT (1) PT1341526E (pt)
RU (1) RU2287999C2 (pt)
SI (1) SI1341526T1 (pt)
SK (1) SK287613B6 (pt)
WO (1) WO2002045754A2 (pt)
ZA (1) ZA200304295B (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60017888T2 (de) 1999-04-05 2006-01-19 Emisphere Technologies, Inc. Dinatrium-salze, monohydrate und ethanol-solvate
CN101837120A (zh) * 2001-06-01 2010-09-22 诺瓦提斯公司 口服施用甲状旁腺激素和降钙素
US20050054557A1 (en) * 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin
TW200403052A (en) * 2002-07-17 2004-03-01 Novartis Ag Use of organic compounds
AR040737A1 (es) * 2002-08-01 2005-04-20 Novartis Ag Administracion oral de calcitonina
EP1603553B9 (en) * 2003-03-17 2012-06-20 Japan Tobacco Inc. Pharmaceutical compositions of cetp inhibitors
TWI393560B (zh) * 2003-05-02 2013-04-21 Japan Tobacco Inc 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合
JP5032844B2 (ja) * 2003-07-11 2012-09-26 ノバルティス アーゲー 微粉末形態の送達物質を含む経口投与用医薬組成物
TR201910447T4 (tr) * 2003-09-12 2019-08-21 Amgen Inc Sinakalset HCI'nin hızlı çözünme formülasyonu.
US9498487B2 (en) * 2004-05-19 2016-11-22 Emisphere Technologies, Inc. Topical cromolyn formulations
GB0422644D0 (en) * 2004-10-12 2004-11-10 Novartis Ag Organic compounds
GB0427603D0 (en) 2004-12-16 2005-01-19 Novartis Ag Organic compounds
JP5175553B2 (ja) * 2005-02-01 2013-04-03 エミスフェアー・テクノロジーズ・インク 胃内滞留および制御放出型送達系
US8030271B2 (en) * 2005-07-05 2011-10-04 Emisphere Technologies, Inc. Compositions and methods for buccal delivery of human growth hormone
NZ566397A (en) 2005-09-19 2010-04-30 Emisphere Tech Inc Crystalline forms of the di-sodium salt of 5-CNAC
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
AU2006318815B2 (en) * 2005-11-17 2010-08-19 Novartis Ag Pharmaceutical composition
JP2009527504A (ja) * 2006-02-23 2009-07-30 イオメディックス スリープ インターナショナル エスアールエル 良質な睡眠の誘導および維持のための組成物および方法
EP2049137A4 (en) * 2006-08-08 2013-05-01 Univ California SALICYLANILIDES AS AMPLIFIERS OF THE ORAL RELEASE OF THERAPEUTIC PEPTIDES
MX2009002314A (es) * 2006-08-31 2009-03-20 Novartis Ag Composiciones farmaceuticas que comprenden hgh para suministro oral.
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
MX2009009243A (es) * 2007-03-02 2009-09-08 Novartis Ag Administracion oral de una calcitonina.
ES2443817T3 (es) 2007-11-02 2014-02-20 Emisphere Technologies, Inc. Método para tratar la deficiencia de vitamina B12
EP2331072B8 (en) 2008-08-18 2020-08-26 Entera Bio Ltd. Methods and compositions for oral administration of proteins
MX2011009559A (es) * 2009-03-12 2012-01-12 Nordic Bioscience As Tratamiento de la diabetes y el sindrome metabolico.
CN103025327A (zh) * 2010-06-09 2013-04-03 艾米斯菲尔技术公司 口服缺铁疗法
RU2600440C3 (ru) 2010-12-16 2021-12-10 Ново Нордиск А/С Твердые композиции, содержащие агонист glp-1 и соль n-(8-(2-гидроксибензоил)амино)каприловой кислоты
WO2012140117A1 (en) 2011-04-12 2012-10-18 Novo Nordisk A/S Double-acylated glp-1 derivatives
DK2827845T3 (en) 2012-03-22 2019-04-01 Novo Nordisk As COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF
ES2952874T3 (es) 2012-03-22 2023-11-06 Novo Nordisk As Composiciones de péptidos GLP-1 y preparación de estas
RS64942B1 (sr) 2012-03-22 2024-01-31 Novo Nordisk As Kompozicije koje obuhvataju sredstvo za isporuku i njihova priprema
CN104487056A (zh) 2012-06-20 2015-04-01 诺和诺德A/S（股份有限公司） 包含肽和递送剂的片剂制剂
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途
BR112017022857B1 (pt) * 2015-07-08 2023-09-26 Research & Business Foundation Sungkyunkwan University Composto, método para preparar o composto, uso de uma composição
EA036204B1 (ru) * 2015-10-16 2020-10-14 Нобел Илач Санайи Ве Тиджарет А.Ш. Фармацевтические композиции нилотиниба гидрохлорида
CN107080739A (zh) * 2017-04-17 2017-08-22 深圳市泛谷药业股份有限公司 一种用于口服给药的固体快速释放布南色林片及其制备方法
MA53076B1 (fr) 2018-02-02 2023-11-30 Novo Nordisk As Compositions solides comportant un agoniste glp-1, du sel d'acide n-(8-(2-hydroxybenzoyl)amino)caprylate et un lubrifiant
JP2021054781A (ja) * 2019-09-26 2021-04-08 デボン エルエス，リミテッド 共結晶形エフィナコナゾール、及びその製造方法
KR102301743B1 (ko) * 2020-12-29 2021-09-13 대봉엘에스 주식회사 에피나코나졸 경구용 조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015633A (en) 1987-04-27 1991-05-14 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing an ace inhibitor
US5756450A (en) 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
US5002771A (en) 1989-02-06 1991-03-26 Rorer Pharmaceutical Corp. Calcitonin suppository formulations
IT1238072B (it) 1990-01-19 1993-07-03 Sclavo Spa Composizioni farmaceutiche e forme di dosaggio per la somministrazione orale di calcitonina
JPH052771A (ja) * 1991-06-25 1993-01-08 Pioneer Electron Corp 光記録媒体
US5681811A (en) 1993-05-10 1997-10-28 Protein Delivery, Inc. Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
IE950946A1 (en) 1994-12-14 1996-06-26 Enbalt Trading Ltd Pharmaceutical tablet formulations.
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
US5972381A (en) 1996-06-28 1999-10-26 Schering Corporation Solid solution of an antifungal agent with enhanced bioavailability
US5958453A (en) 1996-10-31 1999-09-28 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation with improved buccal disintegrability and/or dissolubility
NZ337131A (en) 1997-02-07 2001-08-31 Emisphere Tech Inc Compounds and compositions for delivering lower amounts of biologically or chemically active agents to animals while still achieving the same blood levels and therapeutic effects
US5773647A (en) 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6655379B2 (en) 1998-03-16 2003-12-02 Nektar Therapeutics Aerosolized active agent delivery
AU3574500A (en) 1999-03-25 2000-10-16 Yuhan Corporation Rapidly disintegrable tablet for oral administration
WO2000059480A1 (en) * 1999-04-05 2000-10-12 Emisphere Technologies, Inc. Lyophilized solid dosage forms and methods of making
DE60017888T2 (de) * 1999-04-05 2006-01-19 Emisphere Technologies, Inc. Dinatrium-salze, monohydrate und ethanol-solvate

Also Published As

Publication number Publication date
KR100847695B1 (ko) 2008-07-23
HUP0302319A2 (hu) 2003-11-28
PL362247A1 (en) 2004-10-18
JP2004515480A (ja) 2004-05-27
SK6882003A3 (en) 2004-01-08
DK1341526T3 (da) 2011-10-03
US20020123459A1 (en) 2002-09-05
NO332936B1 (no) 2013-02-04
JP2009185052A (ja) 2009-08-20
ATE513541T1 (de) 2011-07-15
CN1479612A (zh) 2004-03-03
CZ20031566A3 (cs) 2003-09-17
NO20032511D0 (no) 2003-06-03
AU2002234547B2 (en) 2005-03-24
PL209703B1 (pl) 2011-10-31
HU230632B1 (hu) 2017-05-29
CY1112562T1 (el) 2016-02-10
CA2436599C (en) 2011-01-25
CZ305418B6 (cs) 2015-09-09
EP1341526A2 (en) 2003-09-10
CA2436599A1 (en) 2002-06-13
SK287613B6 (sk) 2011-04-05
US7049283B2 (en) 2006-05-23
BRPI0115965B1 (pt) 2017-09-26
EP1341526B1 (en) 2011-06-22
ZA200304295B (en) 2004-05-10
NO20032511L (no) 2003-06-03
AU3454702A (en) 2002-06-18
ECSP034639A (es) 2003-07-25
IL155992A (en) 2008-04-13
ES2367009T3 (es) 2011-10-27
IL155992A0 (en) 2003-12-23
WO2002045754A2 (en) 2002-06-13
RU2287999C2 (ru) 2006-11-27
NZ526196A (en) 2005-01-28
KR20040018309A (ko) 2004-03-03
SI1341526T1 (sl) 2011-10-28
HUP0302319A3 (en) 2013-04-29
HK1059565A1 (en) 2004-07-09
WO2002045754A3 (en) 2003-01-03
BR0115965A (pt) 2003-10-28
MXPA03005096A (es) 2003-09-05
JP4898078B2 (ja) 2012-03-14
CN1304048C (zh) 2007-03-14

Similar Documents

Publication Publication Date Title
IL155992A0 (en) Pharmaceutical compositions for the oral delivery of pharmacologically active agents
HK1089950A1 (en) Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form
ITMI20001173A0 (it) Composizioni farmaceutiche a rilascio prolungato per la somministrazione parenterale di sostanze idrofile biologicamente attiva.
PL348734A1 (en) New sustained release oral formulations
IL166561A0 (en) Pharmaceutical compositions
GEP20074047B (en) Pramipexole once-daily dosage form
YU68199A (sh) Farmaceutske formulacije koje sadrže vorikonazol
AU2001283563A1 (en) Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent
NZ527157A (en) Compositions for delivering bisphosphonates
IL157741A0 (en) Pharmaceutical compositions containing an antihyperplastic active agent
IS6263A (is) Lyfjasamsetningar, sem innihalda trípeptíð
MXPA03010761A (es) Combinaciones farmaceuticas.
IL151909A0 (en) Peptide conjugates for drug delivery
ATE252377T1 (de) Kontrolliert freisetzende pharmazeutische zusammensetzung mit tilidinmesylat als wirkstoff
IL157540A0 (en) N-(aryl)-2-arylethenesulphonamides and therapeutic uses thereof
WO2003041656A3 (en) Soluble drug extended release system
HUP0303860A3 (en) A pharmaceutical tablet having a high active ingredient
MY128759A (en) Oral controlled release formulations
MY136370A (en) Oxazolidinone tablet formulation
MXPA01008348A (es) Microcapsulas para la liberacion prolongada de farmacos.
AU5654701A (en) Drug delivery mask
DE69904020D1 (de) Pharmazeutische zusammensetzung zur nasalen verabreichung von thiocolchicosid