ATE513541T1 - Pharmazeutische zusammensetzungen zur oralen verabreichung von calcitonin - Google Patents

Pharmazeutische zusammensetzungen zur oralen verabreichung von calcitonin

Info

Publication number
ATE513541T1
ATE513541T1 AT01985368T AT01985368T ATE513541T1 AT E513541 T1 ATE513541 T1 AT E513541T1 AT 01985368 T AT01985368 T AT 01985368T AT 01985368 T AT01985368 T AT 01985368T AT E513541 T1 ATE513541 T1 AT E513541T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
calcitonin
pharmacologically active
oral administration
agent
Prior art date
Application number
AT01985368T
Other languages
English (en)
Inventor
Joseph Ault
Moise Azria
Simon Bateman
Joseph Sikora
Gregory Sparta
Rebecca Yang
Jie Xiao
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE513541T1 publication Critical patent/ATE513541T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01985368T 2000-12-06 2001-12-05 Pharmazeutische zusammensetzungen zur oralen verabreichung von calcitonin ATE513541T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25172900P 2000-12-06 2000-12-06
PCT/EP2001/014294 WO2002045754A2 (en) 2000-12-06 2001-12-05 Pharmaceutical compositions for the oral delivery of pharmacologically active agents

Publications (1)

Publication Number Publication Date
ATE513541T1 true ATE513541T1 (de) 2011-07-15

Family

ID=22953160

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01985368T ATE513541T1 (de) 2000-12-06 2001-12-05 Pharmazeutische zusammensetzungen zur oralen verabreichung von calcitonin

Country Status (26)

Country Link
US (1) US7049283B2 (de)
EP (1) EP1341526B1 (de)
JP (2) JP4898078B2 (de)
KR (1) KR100847695B1 (de)
CN (1) CN1304048C (de)
AT (1) ATE513541T1 (de)
AU (2) AU2002234547B2 (de)
BR (2) BR0115965A (de)
CA (1) CA2436599C (de)
CY (1) CY1112562T1 (de)
CZ (1) CZ305418B6 (de)
DK (1) DK1341526T3 (de)
EC (1) ECSP034639A (de)
ES (1) ES2367009T3 (de)
HU (1) HU230632B1 (de)
IL (2) IL155992A0 (de)
MX (1) MXPA03005096A (de)
NO (1) NO332936B1 (de)
NZ (1) NZ526196A (de)
PL (1) PL209703B1 (de)
PT (1) PT1341526E (de)
RU (1) RU2287999C2 (de)
SI (1) SI1341526T1 (de)
SK (1) SK287613B6 (de)
WO (1) WO2002045754A2 (de)
ZA (1) ZA200304295B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2369591C (en) 1999-04-05 2011-06-14 Emisphere Technologies, Inc. Disodium salts, monohydrate, and ethanol solvates
NZ529439A (en) * 2001-06-01 2005-11-25 Novartis Ag Method for orally administering parathyroid hormone (PTH)
US20050054557A1 (en) * 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin
TW200403052A (en) * 2002-07-17 2004-03-01 Novartis Ag Use of organic compounds
TWI307279B (en) * 2002-08-01 2009-03-11 Novartis Ag Oral administration of calcitonin
MXPA05009848A (es) * 2003-03-17 2005-12-06 Japan Tobacco Inc Composiciones farmaceuticas de inhibidores de la proteina de transferencia del ester de colesterilo.
TWI494102B (zh) * 2003-05-02 2015-08-01 Japan Tobacco Inc 包含s-〔2(〔〔1-(2-乙基丁基)環己基〕羰基〕胺基)苯基〕2-甲基丙烷硫酯及hmg輔酶a還原酶抑制劑之組合
AU2004255458B2 (en) * 2003-07-11 2007-09-13 Emisphere Technologies, Inc. Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form
BRPI0412265A (pt) * 2003-07-23 2006-09-05 Novartis Ag uso de calcitonina em osteoartrite
DK3395340T3 (da) * 2003-09-12 2019-07-15 Amgen Inc Hurtigt opløsende formulering af cinacalcet-hcl
AU2005244986B2 (en) * 2004-05-19 2011-01-27 Emisphere Technologies, Inc. Topical cromolyn formulations
GB0422644D0 (en) * 2004-10-12 2004-11-10 Novartis Ag Organic compounds
GB0427603D0 (en) * 2004-12-16 2005-01-19 Novartis Ag Organic compounds
EP1843755B1 (de) * 2005-02-01 2015-04-01 Emisphere Technologies, Inc. System zur magenretention und zur gesteuerten freisetzung
US8030271B2 (en) * 2005-07-05 2011-10-04 Emisphere Technologies, Inc. Compositions and methods for buccal delivery of human growth hormone
JP2009508875A (ja) 2005-09-19 2009-03-05 エミスフェアー・テクノロジーズ・インク N−(5−クロロサリチロイル)−8−アミノカプリル酸二ナトリウム塩の結晶形
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
RU2469709C2 (ru) * 2005-11-17 2012-12-20 Новартис Аг Фармацевтическая композиция
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
AU2007284801A1 (en) * 2006-08-08 2008-02-21 The Regents Of The University Of Californina Salicylanilides enhance oral delivery of therapeutic peptides
EP2059260B1 (de) * 2006-08-31 2013-06-19 Novartis AG Pharmazeutische Zusammensetzungen mit hGH zur oralen Verabreichung
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
AU2008223108B2 (en) * 2007-03-02 2013-10-10 Novartis Ag Oral administration of a calcitonin
PL2215047T3 (pl) 2007-11-02 2014-05-30 Emisphere Tech Inc Sposób leczenia niedoborów witaminy b12
AU2009283821B2 (en) * 2008-08-18 2014-05-29 Entera Bio Ltd. Methods and compositions for oral administration of proteins
CN102369018B (zh) * 2009-03-12 2016-08-03 关键生物科学有限公司 糖尿病和代谢综合征的治疗
CN103025327A (zh) 2010-06-09 2013-04-03 艾米斯菲尔技术公司 口服缺铁疗法
HRP20180425T1 (hr) 2010-12-16 2018-04-20 Novo Nordisk A/S Čvrste kompozicije koje sadrže agonist glp-1 i sol n-(8-(2-hidroksibenzoil)amino)kaprilne kiseline
BR112013026195A2 (pt) 2011-04-12 2016-11-29 Novo Nordisk As derivados de glp-1 duplamente acilados
WO2013139695A1 (en) 2012-03-22 2013-09-26 Novo Nordisk A/S Compositions comprising a delivery agent and preparation thereof
SMT201800491T1 (it) 2012-03-22 2018-11-09 Novo Nordisk As Composizioni di peptidi glp-1 e relativa preparazione
PT2827845T (pt) 2012-03-22 2019-03-29 Novo Nordisk As Composições compreendendo um agente de entrega e sua preparação
JP6517690B2 (ja) 2012-06-20 2019-05-22 ノヴォ ノルディスク アー/エス ペプチド及び送達剤を含む錠剤製剤
ES2688462T3 (es) 2013-05-02 2018-11-02 Novo Nordisk A/S Dosificación oral de compuestos de GLP-1
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途
KR101963559B1 (ko) * 2015-07-08 2019-03-28 한국화학연구원 피롤리딘 카복스아미도 유도체 및 이의 제조 방법 및 용도
EA036204B1 (ru) * 2015-10-16 2020-10-14 Нобел Илач Санайи Ве Тиджарет А.Ш. Фармацевтические композиции нилотиниба гидрохлорида
CN107080739A (zh) * 2017-04-17 2017-08-22 深圳市泛谷药业股份有限公司 一种用于口服给药的固体快速释放布南色林片及其制备方法
EP3746111B1 (de) 2018-02-02 2023-07-19 Novo Nordisk A/S Feste zusammensetzungen mit einem glp-1-agonisten, einem salz aus n-(8-(2-hydroxybenzoyl)amino)caprylsäure und einem schmierstoff
JP2021054781A (ja) * 2019-09-26 2021-04-08 デボン エルエス,リミテッド 共結晶形エフィナコナゾール、及びその製造方法
KR102301743B1 (ko) * 2020-12-29 2021-09-13 대봉엘에스 주식회사 에피나코나졸 경구용 조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015633A (en) 1987-04-27 1991-05-14 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing an ace inhibitor
US5756450A (en) 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
US5002771A (en) 1989-02-06 1991-03-26 Rorer Pharmaceutical Corp. Calcitonin suppository formulations
IT1238072B (it) 1990-01-19 1993-07-03 Sclavo Spa Composizioni farmaceutiche e forme di dosaggio per la somministrazione orale di calcitonina
JPH052771A (ja) * 1991-06-25 1993-01-08 Pioneer Electron Corp 光記録媒体
US5681811A (en) 1993-05-10 1997-10-28 Protein Delivery, Inc. Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
AU4353996A (en) 1994-12-14 1996-07-03 Bioglan Ireland (R & D) Limited Pharmaceutical tablet formulations for direct compression
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
US5972381A (en) 1996-06-28 1999-10-26 Schering Corporation Solid solution of an antifungal agent with enhanced bioavailability
EP0839526A3 (de) * 1996-10-31 1999-01-07 Takeda Chemical Industries, Ltd. Festes pharmazeutisches Präparat mit schneller Auflösungs- oder Disintegrationeigenschaften
DK0993831T3 (da) 1997-02-07 2008-03-25 Emisphere Tech Inc Forbindelser og præparater til tilförsel af aktive stoffer
US5773647A (en) 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
HRP20000608A2 (en) 1998-03-16 2001-04-30 Inhale Therapeutic Syst Aerosolized active agent delivery
WO2000057857A1 (en) 1999-03-25 2000-10-05 Yuhan Corporation Rapidly disintegrable tablet for oral administration
AU4218400A (en) * 1999-04-05 2000-10-23 Emisphere Technologies, Inc. Lyophilized solid dosage forms and methods of making
CA2369591C (en) * 1999-04-05 2011-06-14 Emisphere Technologies, Inc. Disodium salts, monohydrate, and ethanol solvates

Also Published As

Publication number Publication date
CA2436599C (en) 2011-01-25
PL362247A1 (en) 2004-10-18
EP1341526A2 (de) 2003-09-10
SI1341526T1 (sl) 2011-10-28
PL209703B1 (pl) 2011-10-31
HK1059565A1 (en) 2004-07-09
AU2002234547B2 (en) 2005-03-24
IL155992A (en) 2008-04-13
US20020123459A1 (en) 2002-09-05
JP2004515480A (ja) 2004-05-27
HUP0302319A2 (hu) 2003-11-28
HUP0302319A3 (en) 2013-04-29
CN1479612A (zh) 2004-03-03
ES2367009T3 (es) 2011-10-27
JP4898078B2 (ja) 2012-03-14
JP2009185052A (ja) 2009-08-20
HU230632B1 (hu) 2017-05-29
BRPI0115965B1 (pt) 2017-09-26
KR100847695B1 (ko) 2008-07-23
CZ20031566A3 (cs) 2003-09-17
WO2002045754A2 (en) 2002-06-13
NO20032511D0 (no) 2003-06-03
AU3454702A (en) 2002-06-18
CY1112562T1 (el) 2016-02-10
EP1341526B1 (de) 2011-06-22
SK287613B6 (sk) 2011-04-05
NZ526196A (en) 2005-01-28
IL155992A0 (en) 2003-12-23
CZ305418B6 (cs) 2015-09-09
RU2287999C2 (ru) 2006-11-27
NO332936B1 (no) 2013-02-04
SK6882003A3 (en) 2004-01-08
NO20032511L (no) 2003-06-03
MXPA03005096A (es) 2003-09-05
ZA200304295B (en) 2004-05-10
ECSP034639A (es) 2003-07-25
PT1341526E (pt) 2011-09-01
KR20040018309A (ko) 2004-03-03
WO2002045754A3 (en) 2003-01-03
CN1304048C (zh) 2007-03-14
CA2436599A1 (en) 2002-06-13
BR0115965A (pt) 2003-10-28
US7049283B2 (en) 2006-05-23
DK1341526T3 (da) 2011-10-03

Similar Documents

Publication Publication Date Title
ATE513541T1 (de) Pharmazeutische zusammensetzungen zur oralen verabreichung von calcitonin
ITMI20001173A0 (it) Composizioni farmaceutiche a rilascio prolungato per la somministrazione parenterale di sostanze idrofile biologicamente attiva.
ATE442158T1 (de) Oral verabreichte pharmazeutische zusammensetzungen mit einem abgabemittel in mikronisierter form
DE60335557D1 (de) Pharmazeutische zusammensetzungen enthaltend ein opioidanalgetikum
BG66093B1 (bg) Състави с контролирано освобождаване, съдържащи нимесулид
DE69906518D1 (de) Arzneistoff-abgabesystem enthaltend eine festgepackte, feste arzneistoffbasis
ID27504A (id) Formulasi oral baru
CY1111698T1 (el) Συνδυασμος που περιλαμβανει εναν ανταγωνιστη υποδοχεα ατ1 και εναν ενισχυτη εκκρισης ινσουλινης ή εναν ευαισθητοποιητη ινσουλινης
CY1110906T1 (el) Φαρμακευτικη συνθεση για ρινικη χορηγηση φεντανυλης
ATE252377T1 (de) Kontrolliert freisetzende pharmazeutische zusammensetzung mit tilidinmesylat als wirkstoff
DE60102590T2 (de) Darreichungsformen zur behandlung von oralen mykosen
ATE297760T1 (de) Pharmazeutische zusammensetzungen enthaltend terbinafin
ATE460934T1 (de) Pharmazeutische zubereitungen von ciprofloxacin
DE69904020D1 (de) Pharmazeutische zusammensetzung zur nasalen verabreichung von thiocolchicosid
BR0111018A (pt) Formulações estáveis lìquidas e sólidas
DE50005282D1 (de) Medikament sowie aufeinander abgestimmte kombination von medikamenten
HRP20070081T5 (hr) Nazalni farmaceutski pripravak piribedila
PA8531801A1 (es) Formulaciones estabilizadas que comprenden composiciones hidroliticamente inestables
UY27017A1 (es) Composiciones hidrolíticamente inestables

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1341526

Country of ref document: EP