ECSP034639A - Composiciones farmaceuticas para el suministro oral de agente farmacológicamente activos - Google Patents

Composiciones farmaceuticas para el suministro oral de agente farmacológicamente activos

Info

Publication number
ECSP034639A
ECSP034639A EC2003004639A ECSP034639A ECSP034639A EC SP034639 A ECSP034639 A EC SP034639A EC 2003004639 A EC2003004639 A EC 2003004639A EC SP034639 A ECSP034639 A EC SP034639A EC SP034639 A ECSP034639 A EC SP034639A
Authority
EC
Ecuador
Prior art keywords
pharmacologically active
pharmaceutical compositions
active agent
agent
oral supply
Prior art date
Application number
EC2003004639A
Other languages
English (en)
Inventor
Joseph M Ault
Moise Azria
Simon David Bateman
Joseph Sikora
Gregory Sparta
Rebecca Fai-Ying Yang
Jie Xiao
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP034639A publication Critical patent/ECSP034639A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se dan a conocer composiciones farmacéuticas sólidas adecuadas para el suministro oral de agentes farmacológica mente activos, por ejemplo péptidos, las cuales comprenden una cantidad terapéuticamente efectiva de un agente farmacológica mente activo, una crospovidona o providona, y un agente de suministro para este agente farmacológica mente activo,. Las composiciones proporcionan una excelente biodisponiblidad oral de los agentes farmacológica mente activos, en particular calcitonina
EC2003004639A 2000-12-06 2003-06-04 Composiciones farmaceuticas para el suministro oral de agente farmacológicamente activos ECSP034639A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25172900P 2000-12-06 2000-12-06

Publications (1)

Publication Number Publication Date
ECSP034639A true ECSP034639A (es) 2003-07-25

Family

ID=22953160

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004639A ECSP034639A (es) 2000-12-06 2003-06-04 Composiciones farmaceuticas para el suministro oral de agente farmacológicamente activos

Country Status (27)

Country Link
US (1) US7049283B2 (es)
EP (1) EP1341526B1 (es)
JP (2) JP4898078B2 (es)
KR (1) KR100847695B1 (es)
CN (1) CN1304048C (es)
AT (1) ATE513541T1 (es)
AU (2) AU2002234547B2 (es)
BR (2) BRPI0115965B1 (es)
CA (1) CA2436599C (es)
CY (1) CY1112562T1 (es)
CZ (1) CZ305418B6 (es)
DK (1) DK1341526T3 (es)
EC (1) ECSP034639A (es)
ES (1) ES2367009T3 (es)
HK (1) HK1059565A1 (es)
HU (1) HU230632B1 (es)
IL (2) IL155992A0 (es)
MX (1) MXPA03005096A (es)
NO (1) NO332936B1 (es)
NZ (1) NZ526196A (es)
PL (1) PL209703B1 (es)
PT (1) PT1341526E (es)
RU (1) RU2287999C2 (es)
SI (1) SI1341526T1 (es)
SK (1) SK287613B6 (es)
WO (1) WO2002045754A2 (es)
ZA (1) ZA200304295B (es)

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DE60218842T2 (de) * 2001-06-01 2007-12-20 Novartis Ag Orale verabreichung von parathyroidhormon und calcitonin
US20050054557A1 (en) * 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin
TW200403052A (en) * 2002-07-17 2004-03-01 Novartis Ag Use of organic compounds
TWI307279B (en) * 2002-08-01 2009-03-11 Novartis Ag Oral administration of calcitonin
US20040225018A1 (en) * 2003-03-17 2004-11-11 Japan Tobacco Inc. Pharmaceutical compositions of CETP inhibitors
TWI393560B (zh) * 2003-05-02 2013-04-21 Japan Tobacco Inc 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合
PL1651248T3 (pl) * 2003-07-11 2010-02-26 Novartis Ag Doustnie dawkowana kompozycja farmaceutyczna zawierająca środek dostarczający w postaci mikronizowanej
DK1663182T4 (da) * 2003-09-12 2020-02-17 Amgen Inc Hurtigt opløsende formulering af cinacalcet HCI
US9498487B2 (en) * 2004-05-19 2016-11-22 Emisphere Technologies, Inc. Topical cromolyn formulations
GB0422644D0 (en) * 2004-10-12 2004-11-10 Novartis Ag Organic compounds
GB0427603D0 (en) * 2004-12-16 2005-01-19 Novartis Ag Organic compounds
WO2006084164A2 (en) * 2005-02-01 2006-08-10 Emisphere Technologies, Inc. Gastric retention and controlled release delivery system
US8030271B2 (en) * 2005-07-05 2011-10-04 Emisphere Technologies, Inc. Compositions and methods for buccal delivery of human growth hormone
KR20080049128A (ko) 2005-09-19 2008-06-03 에미스페어 테크놀로지스, 인코포레이티드 Ｎ-(5-클로로살리실로일)-8-아미노카프릴산 이나트륨염의결정형
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
WO2007061829A2 (en) * 2005-11-17 2007-05-31 Novartis Ag Pharmaceutical composition
US7476405B2 (en) * 2006-02-23 2009-01-13 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
WO2008021088A2 (en) * 2006-08-08 2008-02-21 The Regents Of The University Of Californina Salicylanilides enhance oral delivery of therapeutic peptides
ES2426485T3 (es) * 2006-08-31 2013-10-23 Novartis Ag Composiciones farmacéuticas que comprenden hGH para administración oral
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
ES2365648T3 (es) * 2007-03-02 2011-10-07 Novartis Ag Administración oral de una calcitonina.
PL2215047T3 (pl) 2007-11-02 2014-05-30 Emisphere Tech Inc Sposób leczenia niedoborów witaminy b12
EP2331072B8 (en) 2008-08-18 2020-08-26 Entera Bio Ltd. Methods and compositions for oral administration of proteins
EP2405934B1 (en) * 2009-03-12 2014-03-26 Nordic Bioscience A/S Treatment of diabetes and metabolic syndrome
JP5865903B2 (ja) * 2010-06-09 2016-02-17 エミスフェアー・テクノロジーズ・インク 経口鉄欠乏療法
DK2651398T3 (en) 2010-12-16 2018-03-12 Novo Nordisk As Solid compositions comprising a GLP-1 agonist and a salt of N- (8- (2-hydroxybenzyl) amino) caprylic acid
KR101972836B1 (ko) 2011-04-12 2019-04-29 노보 노르디스크 에이/에스 이중 아실화된 ｇｌｐ-1 유도체
CN111494324B (zh) 2012-03-22 2023-05-16 诺和诺德股份有限公司 包含递送剂的组合物及其制备
RS57727B1 (sr) 2012-03-22 2018-12-31 Novo Nordisk As Kompozicije glp-1 peptida i njihovo dobijanje
DK2827845T3 (en) 2012-03-22 2019-04-01 Novo Nordisk As COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF
CN104487056A (zh) 2012-06-20 2015-04-01 诺和诺德A/S（股份有限公司） 包含肽和递送剂的片剂制剂
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途
KR101963559B1 (ko) * 2015-07-08 2019-03-28 한국화학연구원 피롤리딘 카복스아미도 유도체 및 이의 제조 방법 및 용도
EA036204B1 (ru) * 2015-10-16 2020-10-14 Нобел Илач Санайи Ве Тиджарет А.Ш. Фармацевтические композиции нилотиниба гидрохлорида
CN107080739A (zh) * 2017-04-17 2017-08-22 深圳市泛谷药业股份有限公司 一种用于口服给药的固体快速释放布南色林片及其制备方法
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Also Published As

Publication number Publication date
HU230632B1 (hu) 2017-05-29
DK1341526T3 (da) 2011-10-03
HK1059565A1 (en) 2004-07-09
CZ305418B6 (cs) 2015-09-09
SK6882003A3 (en) 2004-01-08
SI1341526T1 (sl) 2011-10-28
CA2436599C (en) 2011-01-25
WO2002045754A2 (en) 2002-06-13
NZ526196A (en) 2005-01-28
HUP0302319A3 (en) 2013-04-29
MXPA03005096A (es) 2003-09-05
CN1304048C (zh) 2007-03-14
PL209703B1 (pl) 2011-10-31
AU3454702A (en) 2002-06-18
NO332936B1 (no) 2013-02-04
CA2436599A1 (en) 2002-06-13
US7049283B2 (en) 2006-05-23
CY1112562T1 (el) 2016-02-10
WO2002045754A3 (en) 2003-01-03
AU2002234547B2 (en) 2005-03-24
PT1341526E (pt) 2011-09-01
CZ20031566A3 (cs) 2003-09-17
JP2004515480A (ja) 2004-05-27
KR100847695B1 (ko) 2008-07-23
SK287613B6 (sk) 2011-04-05
HUP0302319A2 (hu) 2003-11-28
EP1341526A2 (en) 2003-09-10
JP2009185052A (ja) 2009-08-20
ES2367009T3 (es) 2011-10-27
IL155992A0 (en) 2003-12-23
BRPI0115965B1 (pt) 2017-09-26
BR0115965A (pt) 2003-10-28
KR20040018309A (ko) 2004-03-03
US20020123459A1 (en) 2002-09-05
RU2287999C2 (ru) 2006-11-27
EP1341526B1 (en) 2011-06-22
IL155992A (en) 2008-04-13
NO20032511D0 (no) 2003-06-03
JP4898078B2 (ja) 2012-03-14
NO20032511L (no) 2003-06-03
ZA200304295B (en) 2004-05-10
CN1479612A (zh) 2004-03-03
ATE513541T1 (de) 2011-07-15
PL362247A1 (en) 2004-10-18

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