PT1268469E - N-(heterociclil)benzeno ou piridino-sulfonamidas como agentes anti-tromboticos eanti-coagulantes - Google Patents

N-(heterociclil)benzeno ou piridino-sulfonamidas como agentes anti-tromboticos eanti-coagulantes

Info

Publication number
PT1268469E
PT1268469E PT01919537T PT01919537T PT1268469E PT 1268469 E PT1268469 E PT 1268469E PT 01919537 T PT01919537 T PT 01919537T PT 01919537 T PT01919537 T PT 01919537T PT 1268469 E PT1268469 E PT 1268469E
Authority
PT
Portugal
Prior art keywords
eanti
sulfonamid
coagulating
heterocyclyl
pyridine
Prior art date
Application number
PT01919537T
Other languages
English (en)
Portuguese (pt)
Inventor
Gerard Cremer
Jean-Michel Altenburger
Gilbert Lassalle
Mostafa Matrougui
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of PT1268469E publication Critical patent/PT1268469E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT01919537T 2000-03-23 2001-03-22 N-(heterociclil)benzeno ou piridino-sulfonamidas como agentes anti-tromboticos eanti-coagulantes PT1268469E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0003724A FR2806722B1 (fr) 2000-03-23 2000-03-23 Derives de n-(heterocyclylbutyl) benzene-ou pyridine sulfonamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
PT1268469E true PT1268469E (pt) 2004-10-29

Family

ID=8848428

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01919537T PT1268469E (pt) 2000-03-23 2001-03-22 N-(heterociclil)benzeno ou piridino-sulfonamidas como agentes anti-tromboticos eanti-coagulantes

Country Status (34)

Country Link
US (1) US6680329B2 (enExample)
EP (1) EP1268469B1 (enExample)
JP (1) JP2003528098A (enExample)
KR (1) KR100791693B1 (enExample)
CN (1) CN1183128C (enExample)
AR (1) AR029900A1 (enExample)
AT (1) ATE269325T1 (enExample)
AU (2) AU2001246617B2 (enExample)
BG (1) BG65863B1 (enExample)
BR (1) BR0109385A (enExample)
CA (1) CA2401637C (enExample)
DE (1) DE60103868T2 (enExample)
DK (1) DK1268469T3 (enExample)
EA (1) EA004986B1 (enExample)
EE (1) EE05084B1 (enExample)
ES (1) ES2222358T3 (enExample)
FR (1) FR2806722B1 (enExample)
HR (1) HRP20020762B1 (enExample)
HU (1) HUP0300695A2 (enExample)
IL (2) IL151619A0 (enExample)
IS (1) IS2304B (enExample)
ME (1) MEP17408A (enExample)
MX (1) MXPA02009276A (enExample)
NO (1) NO324835B1 (enExample)
PL (1) PL204660B1 (enExample)
PT (1) PT1268469E (enExample)
RS (1) RS50370B (enExample)
SI (1) SI1268469T1 (enExample)
SK (1) SK286687B6 (enExample)
TR (1) TR200402343T4 (enExample)
TW (1) TWI290141B (enExample)
UA (1) UA71667C2 (enExample)
WO (1) WO2001070736A1 (enExample)
ZA (1) ZA200206996B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2508165C (en) 2002-12-06 2014-05-06 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US7750162B2 (en) 2004-04-19 2010-07-06 Daiso Co., Ltd. Process for preparation of nonnatural amino acid and intermediate thereof
WO2005102991A1 (ja) * 2004-04-19 2005-11-03 Daiso Co., Ltd. 非天然型アミノ酸の製造方法およびその中間体
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
US8586748B2 (en) * 2008-04-09 2013-11-19 Boehringer Ingelheim International Gmbh 2-sulfonylamino-4-heteroaryl butyramide antagonists of CCR10
JP2011522801A (ja) * 2008-05-22 2011-08-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング CCR10のα−置換N−スルホニルグリシン(GYLCINE)アミドアンタゴニスト、それらを含有する組成物およびそれらを使用するための方法
WO2011094496A2 (en) * 2010-01-28 2011-08-04 The Medicines Company Trypsin-like serine protease inhibitors, and their preparation and use
FR2981071B1 (fr) * 2011-10-10 2014-02-07 Centre Nat Rech Scient Synthese versatile et stereospecifique d'acides amines gamma,delta-insatures par la reaction de wittig

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727410B1 (fr) * 1994-11-25 1996-12-20 Synthelabo Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese
FR2728570B1 (fr) * 1994-12-23 1997-04-11 Synthelabo Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique
FR2756285B1 (fr) * 1996-11-22 1998-12-18 Synthelabo Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique
FR2756220B1 (fr) * 1996-11-27 1998-12-24 Lorraine Laminage Roue pour vehicule terrestre a moteur
FR2771094B1 (fr) * 1997-11-19 2000-02-04 Synthelabo Derives de piperidine-2-carboxylate, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ZA200206996B (en) 2003-09-01
IL151619A (en) 2009-05-04
SK286687B6 (sk) 2009-03-05
YU67002A (sh) 2005-07-19
HRP20020762A2 (en) 2003-12-31
AU4661701A (en) 2001-10-03
TR200402343T4 (tr) 2004-12-21
CN1183128C (zh) 2005-01-05
PL364988A1 (en) 2004-12-27
HK1051537A1 (en) 2003-08-08
DK1268469T3 (da) 2004-10-11
BR0109385A (pt) 2003-06-03
UA71667C2 (uk) 2004-12-15
ATE269325T1 (de) 2004-07-15
FR2806722B1 (fr) 2002-05-17
KR20020081476A (ko) 2002-10-26
PL204660B1 (pl) 2010-01-29
IL151619A0 (en) 2003-04-10
EP1268469B1 (fr) 2004-06-16
IS2304B (is) 2007-10-15
TWI290141B (en) 2007-11-21
EA004986B1 (ru) 2004-10-28
CA2401637C (en) 2009-11-10
WO2001070736A1 (fr) 2001-09-27
CN1426407A (zh) 2003-06-25
FR2806722A1 (fr) 2001-09-28
BG107130A (bg) 2003-06-30
NO20024496D0 (no) 2002-09-19
SK13512002A3 (sk) 2003-03-04
AU2001246617B2 (en) 2006-03-02
NO324835B1 (no) 2007-12-17
EA200200838A1 (ru) 2003-04-24
MXPA02009276A (es) 2003-05-23
RS50370B (sr) 2009-11-10
DE60103868D1 (de) 2004-07-22
DE60103868T2 (de) 2005-06-09
EP1268469A1 (fr) 2003-01-02
MEP17408A (en) 2010-06-10
ES2222358T3 (es) 2005-02-01
AR029900A1 (es) 2003-07-23
IS6535A (is) 2002-08-30
BG65863B1 (bg) 2010-03-31
HRP20020762B1 (en) 2005-02-28
EE200200540A (et) 2004-04-15
NO20024496L (no) 2002-11-22
JP2003528098A (ja) 2003-09-24
KR100791693B1 (ko) 2008-01-03
US20030207920A1 (en) 2003-11-06
SI1268469T1 (en) 2004-10-31
US6680329B2 (en) 2004-01-20
HUP0300695A2 (hu) 2003-07-28
EE05084B1 (et) 2008-10-15
CA2401637A1 (en) 2001-09-27

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