BR0109385A - N-(heterociclil) benzeno - ou piridina sulfonamidas como agentes antitrombóticos e anticoagulantes - Google Patents
N-(heterociclil) benzeno - ou piridina sulfonamidas como agentes antitrombóticos e anticoagulantesInfo
- Publication number
- BR0109385A BR0109385A BR0109385-1A BR0109385A BR0109385A BR 0109385 A BR0109385 A BR 0109385A BR 0109385 A BR0109385 A BR 0109385A BR 0109385 A BR0109385 A BR 0109385A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- optionally substituted
- represent
- pyridine
- anticoagulant agents
- Prior art date
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 title abstract 5
- 239000003146 anticoagulant agent Substances 0.000 title abstract 3
- 229940127090 anticoagulant agent Drugs 0.000 title abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 title abstract 2
- 230000002785 anti-thrombosis Effects 0.000 title 1
- 229960004676 antithrombotic agent Drugs 0.000 title 1
- DWJMBQYORXLGAE-UHFFFAOYSA-N pyridine-2-sulfonamide Chemical class NS(=O)(=O)C1=CC=CC=N1 DWJMBQYORXLGAE-UHFFFAOYSA-N 0.000 title 1
- -1 1,2,3,6-tetrahydropyridinyl group Chemical group 0.000 abstract 5
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 4
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000003386 piperidinyl group Chemical group 0.000 abstract 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0003724A FR2806722B1 (fr) | 2000-03-23 | 2000-03-23 | Derives de n-(heterocyclylbutyl) benzene-ou pyridine sulfonamide, leur preparation et leur application en therapeutique |
| PCT/FR2001/000861 WO2001070736A1 (fr) | 2000-03-23 | 2001-03-22 | N-(heterocyclyl)benzene-ou pyridine sulfonamides comme agents antithrombotiques et anticoagulantes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0109385A true BR0109385A (pt) | 2003-06-03 |
Family
ID=8848428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0109385-1A BR0109385A (pt) | 2000-03-23 | 2001-03-22 | N-(heterociclil) benzeno - ou piridina sulfonamidas como agentes antitrombóticos e anticoagulantes |
Country Status (34)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2508165C (en) * | 2002-12-06 | 2014-05-06 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| US7750162B2 (en) | 2004-04-19 | 2010-07-06 | Daiso Co., Ltd. | Process for preparation of nonnatural amino acid and intermediate thereof |
| EP1739077A4 (en) * | 2004-04-19 | 2008-04-16 | Daiso Co Ltd | PROCESS FOR THE PRODUCTION OF NON-NATURAL AMINO ACIDS AND INTERMEDIATES THEREFOR |
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| US8586748B2 (en) * | 2008-04-09 | 2013-11-19 | Boehringer Ingelheim International Gmbh | 2-sulfonylamino-4-heteroaryl butyramide antagonists of CCR10 |
| EP2294051B1 (en) * | 2008-05-22 | 2014-08-13 | Boehringer Ingelheim International GmbH | Alpha-substituted n-sulfonyl gylcine amides antagonists of ccr10, compositions containing the same and methods for using them |
| EA022121B1 (ru) * | 2010-01-28 | 2015-11-30 | Зе Медисинс Компани (Лейпциг) Гмбх | Ингибиторы трипсиноподобных сериновых протеаз, их получение и применение |
| FR2981071B1 (fr) * | 2011-10-10 | 2014-02-07 | Centre Nat Rech Scient | Synthese versatile et stereospecifique d'acides amines gamma,delta-insatures par la reaction de wittig |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2727410B1 (fr) * | 1994-11-25 | 1996-12-20 | Synthelabo | Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese |
| FR2728570B1 (fr) * | 1994-12-23 | 1997-04-11 | Synthelabo | Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique |
| FR2756285B1 (fr) * | 1996-11-22 | 1998-12-18 | Synthelabo | Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique |
| FR2756220B1 (fr) * | 1996-11-27 | 1998-12-24 | Lorraine Laminage | Roue pour vehicule terrestre a moteur |
| FR2771094B1 (fr) * | 1997-11-19 | 2000-02-04 | Synthelabo | Derives de piperidine-2-carboxylate, leur preparation et leur application en therapeutique |
-
2000
- 2000-03-23 FR FR0003724A patent/FR2806722B1/fr not_active Expired - Fee Related
-
2001
- 2001-03-22 SI SI200130152T patent/SI1268469T1/xx unknown
- 2001-03-22 AU AU2001246617A patent/AU2001246617B2/en not_active Ceased
- 2001-03-22 UA UA2002097272A patent/UA71667C2/uk unknown
- 2001-03-22 PT PT01919537T patent/PT1268469E/pt unknown
- 2001-03-22 US US10/221,404 patent/US6680329B2/en not_active Expired - Fee Related
- 2001-03-22 KR KR1020027012432A patent/KR100791693B1/ko not_active Expired - Fee Related
- 2001-03-22 ME MEP-174/08A patent/MEP17408A/xx unknown
- 2001-03-22 EE EEP200200540A patent/EE05084B1/xx not_active IP Right Cessation
- 2001-03-22 ES ES01919537T patent/ES2222358T3/es not_active Expired - Lifetime
- 2001-03-22 TR TR2004/02343T patent/TR200402343T4/xx unknown
- 2001-03-22 PL PL364988A patent/PL204660B1/pl not_active IP Right Cessation
- 2001-03-22 JP JP2001568937A patent/JP2003528098A/ja not_active Ceased
- 2001-03-22 TW TW090106733A patent/TWI290141B/zh active
- 2001-03-22 BR BR0109385-1A patent/BR0109385A/pt not_active Application Discontinuation
- 2001-03-22 MX MXPA02009276A patent/MXPA02009276A/es active IP Right Grant
- 2001-03-22 DK DK01919537T patent/DK1268469T3/da active
- 2001-03-22 WO PCT/FR2001/000861 patent/WO2001070736A1/fr not_active Ceased
- 2001-03-22 IL IL15161901A patent/IL151619A0/xx unknown
- 2001-03-22 CN CNB018084974A patent/CN1183128C/zh not_active Expired - Fee Related
- 2001-03-22 AT AT01919537T patent/ATE269325T1/de active
- 2001-03-22 CA CA002401637A patent/CA2401637C/en not_active Expired - Fee Related
- 2001-03-22 DE DE60103868T patent/DE60103868T2/de not_active Expired - Lifetime
- 2001-03-22 HR HR20020762A patent/HRP20020762B1/xx not_active IP Right Cessation
- 2001-03-22 HU HU0300695A patent/HUP0300695A2/hu unknown
- 2001-03-22 AR ARP010101337A patent/AR029900A1/es active IP Right Grant
- 2001-03-22 EA EA200200838A patent/EA004986B1/ru not_active IP Right Cessation
- 2001-03-22 RS YUP-670/02A patent/RS50370B/sr unknown
- 2001-03-22 EP EP01919537A patent/EP1268469B1/fr not_active Expired - Lifetime
- 2001-03-22 SK SK1351-2002A patent/SK286687B6/sk not_active IP Right Cessation
- 2001-03-22 AU AU4661701A patent/AU4661701A/xx active Pending
-
2002
- 2002-08-30 IS IS6535A patent/IS2304B/is unknown
- 2002-08-30 ZA ZA200206996A patent/ZA200206996B/en unknown
- 2002-09-04 IL IL151619A patent/IL151619A/en not_active IP Right Cessation
- 2002-09-19 NO NO20024496A patent/NO324835B1/no not_active IP Right Cessation
- 2002-09-20 BG BG107130A patent/BG65863B1/bg unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0211995A (pt) | Preparados de combinação de derivados de propanolamina substituìdos por arila com outras substâncias ativas e sua aplicação | |
| BR0114870A (pt) | Tratamento de tumores estromais gastrointestinais | |
| BR0108893A (pt) | Composição farmacêutica, composto e processo de preparação de compostos | |
| BR0212031A (pt) | Preparados de combinação de derivados de 1,1-dióxido de 1-4-benzotiepina com outras substâncias ativas e seu emprego | |
| MA27467A1 (fr) | Quinolones anti-microbiens, leurs compositions et utilisations | |
| BR0109385A (pt) | N-(heterociclil) benzeno - ou piridina sulfonamidas como agentes antitrombóticos e anticoagulantes | |
| DE60234812D1 (de) | Arzneipräparat, das als wirkstoff 5-methyl-1-phenyl-2-(1h)-pyridon enthält | |
| BRPI0112986B8 (pt) | compostos azabicíclicos, processo para a sua preparação, bem como composições farmacêuticas compreendendo os ditos compostos | |
| BR9800884A (pt) | Aplicação de derivados de pirimidina para a prevenção do câncer, por si só ou em combinação com outras medidas terapêuticas. | |
| BR9901111A (pt) | Corantes contendo derivados de diamino-benzeno bem como derivados de diamino-benzeno | |
| MA30717B1 (fr) | Derives de pyridin-3-yle en tant qu'agents immunomodulateurs | |
| BR9917144A (pt) | Composições para lavagem de louçacompreendendo alquilbenzeno sulfonatosmodificados | |
| BR0107811A (pt) | Composição herbicida | |
| AR051288A1 (es) | Derivados de pirazol condensado, su preparacion y su aplicacion terapeutica | |
| ATE286027T1 (de) | Fluorpyrazol-biphenylamide als fungizide | |
| LV10104A (lv) | Pirimidin-4'-tionukleozids | |
| BR0011700A (pt) | Dinitrilas de ácido arilmalÈnico substituìdo como intermediários para a preparação de herbicidas | |
| ES2160649T3 (es) | Nuevos compuestos lactamicos y procedimientos para su preparacion. | |
| DE60112960D1 (de) | Kondensierte pyridoindolderivate | |
| ES2099149T3 (es) | Oxidos de picolina. | |
| DE60121048D1 (de) | PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE | |
| BR9916320A (pt) | Bisamido polibiguanidas e uso das mesmas para desinfetar lentes de contato e preservar composições farmacêuticas | |
| ATE523498T1 (de) | Hiv-inhibierende 2-(4- cyanophenylamino)pyrimidinderivate | |
| BR0205398A (pt) | Derivados de 1,3-dihidroxibenzeno e agentes para tingimento contendo estes compostos | |
| WO2003013499A3 (en) | Drugs for vasculopaties |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |