ATE269325T1 - N-heterocyclyl-benzen oder -pyridin-sulfonamide zur verwendung als anti-thrombogene und antikoagulierende verbindungen - Google Patents
N-heterocyclyl-benzen oder -pyridin-sulfonamide zur verwendung als anti-thrombogene und antikoagulierende verbindungenInfo
- Publication number
- ATE269325T1 ATE269325T1 AT01919537T AT01919537T ATE269325T1 AT E269325 T1 ATE269325 T1 AT E269325T1 AT 01919537 T AT01919537 T AT 01919537T AT 01919537 T AT01919537 T AT 01919537T AT E269325 T1 ATE269325 T1 AT E269325T1
- Authority
- AT
- Austria
- Prior art keywords
- thrombogen
- heterocyclyl
- benzene
- anticoagulant compounds
- pyridine sulfonamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0003724A FR2806722B1 (fr) | 2000-03-23 | 2000-03-23 | Derives de n-(heterocyclylbutyl) benzene-ou pyridine sulfonamide, leur preparation et leur application en therapeutique |
| PCT/FR2001/000861 WO2001070736A1 (fr) | 2000-03-23 | 2001-03-22 | N-(heterocyclyl)benzene-ou pyridine sulfonamides comme agents antithrombotiques et anticoagulantes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE269325T1 true ATE269325T1 (de) | 2004-07-15 |
Family
ID=8848428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01919537T ATE269325T1 (de) | 2000-03-23 | 2001-03-22 | N-heterocyclyl-benzen oder -pyridin-sulfonamide zur verwendung als anti-thrombogene und antikoagulierende verbindungen |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6680329B2 (de) |
| EP (1) | EP1268469B1 (de) |
| JP (1) | JP2003528098A (de) |
| KR (1) | KR100791693B1 (de) |
| CN (1) | CN1183128C (de) |
| AR (1) | AR029900A1 (de) |
| AT (1) | ATE269325T1 (de) |
| AU (2) | AU2001246617B2 (de) |
| BG (1) | BG65863B1 (de) |
| BR (1) | BR0109385A (de) |
| CA (1) | CA2401637C (de) |
| DE (1) | DE60103868T2 (de) |
| DK (1) | DK1268469T3 (de) |
| EA (1) | EA004986B1 (de) |
| EE (1) | EE05084B1 (de) |
| ES (1) | ES2222358T3 (de) |
| FR (1) | FR2806722B1 (de) |
| HK (1) | HK1051537A1 (de) |
| HR (1) | HRP20020762B1 (de) |
| HU (1) | HUP0300695A2 (de) |
| IL (2) | IL151619A0 (de) |
| IS (1) | IS2304B (de) |
| ME (1) | MEP17408A (de) |
| MX (1) | MXPA02009276A (de) |
| NO (1) | NO324835B1 (de) |
| PL (1) | PL204660B1 (de) |
| PT (1) | PT1268469E (de) |
| RS (1) | RS50370B (de) |
| SI (1) | SI1268469T1 (de) |
| SK (1) | SK286687B6 (de) |
| TR (1) | TR200402343T4 (de) |
| TW (1) | TWI290141B (de) |
| UA (1) | UA71667C2 (de) |
| WO (1) | WO2001070736A1 (de) |
| ZA (1) | ZA200206996B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| DE60329415D1 (de) * | 2002-12-06 | 2009-11-05 | Purdue Research Foundation | Pyridine zur behandlung von verletztemsäugetiernervengewebe |
| US7750162B2 (en) | 2004-04-19 | 2010-07-06 | Daiso Co., Ltd. | Process for preparation of nonnatural amino acid and intermediate thereof |
| EP1739077A4 (de) * | 2004-04-19 | 2008-04-16 | Daiso Co Ltd | Verfahren zur herstellung von nicht-natürlichen aminosäuren und zwischenprodukte dafür |
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| US8586748B2 (en) * | 2008-04-09 | 2013-11-19 | Boehringer Ingelheim International Gmbh | 2-sulfonylamino-4-heteroaryl butyramide antagonists of CCR10 |
| EP2294051B1 (de) * | 2008-05-22 | 2014-08-13 | Boehringer Ingelheim International GmbH | Alphasubstituierte n-sulfonylgylcinamid-antagonisten von ccr10, zusammensetzungen damit und verfahren zu ihrer verwendung |
| ES2569983T3 (es) * | 2010-01-28 | 2016-05-13 | The Medicines Company (Leipzig) Gmbh | Inhibidores de serinproteasa de tipo tripsina y su preparación y uso |
| FR2981071B1 (fr) * | 2011-10-10 | 2014-02-07 | Centre Nat Rech Scient | Synthese versatile et stereospecifique d'acides amines gamma,delta-insatures par la reaction de wittig |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2727410B1 (fr) * | 1994-11-25 | 1996-12-20 | Synthelabo | Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese |
| FR2728570B1 (fr) * | 1994-12-23 | 1997-04-11 | Synthelabo | Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique |
| FR2756285B1 (fr) * | 1996-11-22 | 1998-12-18 | Synthelabo | Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique |
| FR2756220B1 (fr) * | 1996-11-27 | 1998-12-24 | Lorraine Laminage | Roue pour vehicule terrestre a moteur |
| FR2771094B1 (fr) * | 1997-11-19 | 2000-02-04 | Synthelabo | Derives de piperidine-2-carboxylate, leur preparation et leur application en therapeutique |
-
2000
- 2000-03-23 FR FR0003724A patent/FR2806722B1/fr not_active Expired - Fee Related
-
2001
- 2001-03-22 UA UA2002097272A patent/UA71667C2/uk unknown
- 2001-03-22 DK DK01919537T patent/DK1268469T3/da active
- 2001-03-22 EP EP01919537A patent/EP1268469B1/de not_active Expired - Lifetime
- 2001-03-22 MX MXPA02009276A patent/MXPA02009276A/es active IP Right Grant
- 2001-03-22 BR BR0109385-1A patent/BR0109385A/pt not_active Application Discontinuation
- 2001-03-22 HU HU0300695A patent/HUP0300695A2/hu unknown
- 2001-03-22 TR TR2004/02343T patent/TR200402343T4/xx unknown
- 2001-03-22 PT PT01919537T patent/PT1268469E/pt unknown
- 2001-03-22 IL IL15161901A patent/IL151619A0/xx unknown
- 2001-03-22 DE DE60103868T patent/DE60103868T2/de not_active Expired - Lifetime
- 2001-03-22 AU AU2001246617A patent/AU2001246617B2/en not_active Ceased
- 2001-03-22 SI SI200130152T patent/SI1268469T1/xx unknown
- 2001-03-22 PL PL364988A patent/PL204660B1/pl not_active IP Right Cessation
- 2001-03-22 TW TW090106733A patent/TWI290141B/zh active
- 2001-03-22 EE EEP200200540A patent/EE05084B1/xx not_active IP Right Cessation
- 2001-03-22 AU AU4661701A patent/AU4661701A/xx active Pending
- 2001-03-22 SK SK1351-2002A patent/SK286687B6/sk not_active IP Right Cessation
- 2001-03-22 EA EA200200838A patent/EA004986B1/ru not_active IP Right Cessation
- 2001-03-22 RS YUP-670/02A patent/RS50370B/sr unknown
- 2001-03-22 ME MEP-174/08A patent/MEP17408A/xx unknown
- 2001-03-22 AR ARP010101337A patent/AR029900A1/es active IP Right Grant
- 2001-03-22 WO PCT/FR2001/000861 patent/WO2001070736A1/fr active IP Right Grant
- 2001-03-22 JP JP2001568937A patent/JP2003528098A/ja not_active Ceased
- 2001-03-22 US US10/221,404 patent/US6680329B2/en not_active Expired - Fee Related
- 2001-03-22 ES ES01919537T patent/ES2222358T3/es not_active Expired - Lifetime
- 2001-03-22 CA CA002401637A patent/CA2401637C/en not_active Expired - Fee Related
- 2001-03-22 KR KR1020027012432A patent/KR100791693B1/ko not_active IP Right Cessation
- 2001-03-22 AT AT01919537T patent/ATE269325T1/de active
- 2001-03-22 CN CNB018084974A patent/CN1183128C/zh not_active Expired - Fee Related
-
2002
- 2002-08-30 ZA ZA200206996A patent/ZA200206996B/en unknown
- 2002-08-30 IS IS6535A patent/IS2304B/is unknown
- 2002-09-04 IL IL151619A patent/IL151619A/en not_active IP Right Cessation
- 2002-09-19 HR HR20020762A patent/HRP20020762B1/xx not_active IP Right Cessation
- 2002-09-19 NO NO20024496A patent/NO324835B1/no not_active IP Right Cessation
- 2002-09-20 BG BG107130A patent/BG65863B1/bg unknown
-
2003
- 2003-05-27 HK HK03103771A patent/HK1051537A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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