DK1280801T3 - Hydantoinholdige glucokinaseaktivatorer - Google Patents
Hydantoinholdige glucokinaseaktivatorerInfo
- Publication number
- DK1280801T3 DK1280801T3 DK01925563T DK01925563T DK1280801T3 DK 1280801 T3 DK1280801 T3 DK 1280801T3 DK 01925563 T DK01925563 T DK 01925563T DK 01925563 T DK01925563 T DK 01925563T DK 1280801 T3 DK1280801 T3 DK 1280801T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydantoin
- glucokinase activators
- containing glucokinase
- activators
- glucokinase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20149800P | 2000-05-03 | 2000-05-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1280801T3 true DK1280801T3 (da) | 2006-01-23 |
Family
ID=22746054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01925563T DK1280801T3 (da) | 2000-05-03 | 2001-04-23 | Hydantoinholdige glucokinaseaktivatorer |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6583288B2 (da) |
| EP (1) | EP1280801B1 (da) |
| JP (1) | JP3842131B2 (da) |
| KR (1) | KR100505312B1 (da) |
| CN (1) | CN1209361C (da) |
| AR (1) | AR034253A1 (da) |
| AT (1) | ATE304011T1 (da) |
| AU (2) | AU5227001A (da) |
| BR (1) | BR0110492A (da) |
| CA (1) | CA2407428C (da) |
| DE (1) | DE60113247T2 (da) |
| DK (1) | DK1280801T3 (da) |
| EC (1) | ECSP014055A (da) |
| ES (1) | ES2248309T3 (da) |
| MX (1) | MXPA02010746A (da) |
| PE (1) | PE20011313A1 (da) |
| PT (1) | PT1280801E (da) |
| UY (1) | UY26689A1 (da) |
| WO (1) | WO2001083478A2 (da) |
| ZA (1) | ZA200208370B (da) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2248309T3 (es) * | 2000-05-03 | 2006-03-16 | F. Hoffmann-La Roche Ag | Activadores de glucoquinasa conteniendo hidantoina. |
| US6482951B2 (en) * | 2000-12-13 | 2002-11-19 | Hoffmann-La Roche Inc. | Isoindolin-1-one glucokinase activators |
| SE0102299D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
| SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
| CZ2004747A3 (cs) | 2001-12-21 | 2004-11-10 | Novo Nordisk A/S | Deriváty amidů jako GK aktivátory |
| RU2340605C2 (ru) | 2002-06-27 | 2008-12-10 | Ново Нордиск А/С | Арилкарбонильные производные в качестве терапевтических средств |
| JP4881559B2 (ja) | 2002-06-27 | 2012-02-22 | ノボ・ノルデイスク・エー／エス | 治療薬としてのアリールカルボニル誘導体 |
| CA2498089A1 (en) | 2002-10-03 | 2004-06-17 | Novartis Ag | Substituted (thiazol-2-yl) -amide or sulfonamide as glycokinase activators useful in the treatment of type 2 diabetes |
| GB0226931D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
| MY141521A (en) * | 2002-12-12 | 2010-05-14 | Hoffmann La Roche | 5-substituted-six-membered heteroaromatic glucokinase activators |
| JP4621198B2 (ja) * | 2003-02-11 | 2011-01-26 | プロシディオン・リミテッド | トリ（シクロ）置換アミドグルコキナーゼ活性化化合物 |
| PL378117A1 (pl) | 2003-02-11 | 2006-03-06 | Prosidion Limited | Tricyklopodstawione związki amidowe |
| DK1723128T3 (da) * | 2004-01-06 | 2013-02-18 | Novo Nordisk As | Heteroarylurinstoffer og deres anvendelse som glucokinaseaktivatorer |
| CN1910166B (zh) * | 2004-01-06 | 2012-01-04 | 诺和诺德公司 | 杂芳基脲及其作为葡糖激酶活化剂的用途 |
| CA2560689C (en) | 2004-04-02 | 2011-03-01 | Novartis Ag | Sulfonamide-thiazolpyridine derivatives as glucokinase activators useful in the treatment of type 2 diabetes |
| CA2561157A1 (en) | 2004-04-02 | 2005-10-13 | Novartis Ag | Thiazolopyridine derivatives, pharmaceutical conditions containing them and methods of treating glucokinase mediated conditions |
| MX2007001846A (es) * | 2004-08-17 | 2007-03-28 | Hoffmann La Roche | Hidantoinas sustituidas. |
| CA2579717A1 (en) * | 2004-09-09 | 2006-03-23 | Merck & Co., Inc. | Tricyclic anilide spirolactam cgrp receptor antagonists |
| EP1797073B1 (en) * | 2004-09-13 | 2010-04-14 | Merck Sharp & Dohme Corp. | Bicyclic anilide spirolactam cgrp receptor antagonists |
| US7390798B2 (en) * | 2004-09-13 | 2008-06-24 | Merck & Co., Inc. | Carboxamide spirolactam CGRP receptor antagonists |
| TW200621766A (en) * | 2004-09-17 | 2006-07-01 | Hoffmann La Roche | Substituted hydantoins |
| CA2614518A1 (en) | 2005-07-08 | 2007-01-18 | Novo-Nordisk A/S | Dicycloalkyl urea glucokinase activators |
| WO2007015805A1 (en) | 2005-07-20 | 2007-02-08 | Eli Lilly And Company | 1-amino linked compounds |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| EP1931337B1 (en) | 2005-09-29 | 2013-10-23 | Sanofi | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
| GT200600428A (es) | 2005-09-30 | 2007-05-21 | Compuestos organicos | |
| GT200600429A (es) | 2005-09-30 | 2007-04-30 | Compuestos organicos | |
| JP5198280B2 (ja) | 2005-11-17 | 2013-05-15 | イーライ リリー アンド カンパニー | グルカゴン受容体アンタゴニスト、並びにその調製及び治療への使用 |
| EP1948614A2 (en) * | 2005-11-18 | 2008-07-30 | Takeda San Diego, Inc. | Glucokinase activators |
| FR2894962B1 (fr) * | 2005-12-20 | 2008-03-14 | Pharmamens Sarl | Hydantoines a action insulinotropique |
| US7612212B2 (en) * | 2006-02-22 | 2009-11-03 | Hoffmann-La Roche Inc. | Substituted hydantoins |
| WO2007104034A2 (en) * | 2006-03-08 | 2007-09-13 | Takeda San Diego, Inc. | Glucokinase activators |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| ATE522518T1 (de) | 2006-05-31 | 2011-09-15 | Takeda San Diego Inc | Indazol- und isoindolderivate als glucokinaseaktivierende stoffe |
| US20080107725A1 (en) * | 2006-10-13 | 2008-05-08 | Albano Antonio A | Pharmaceutical Solid Dosage Forms Comprising Amorphous Compounds Micro-Embedded in Ionic Water-Insoluble Polymers |
| JP5419706B2 (ja) * | 2006-12-20 | 2014-02-19 | タケダ カリフォルニア インコーポレイテッド | グルコキナーゼアクチベーター |
| TW200831081A (en) | 2006-12-25 | 2008-08-01 | Kyorin Seiyaku Kk | Glucokinase activator |
| KR20090121376A (ko) * | 2007-03-07 | 2009-11-25 | 교린 세이야꾸 가부시키 가이샤 | 글루코키나아제 활성화 물질 |
| CA2680307A1 (en) * | 2007-03-12 | 2008-09-18 | Merck & Co., Inc. | Monocyclic anilide spirolactam cgrp receptor antagonists |
| WO2008116107A2 (en) | 2007-03-21 | 2008-09-25 | Takeda San Diego, Inc. | Piperazine derivatives as glucokinase activators |
| MX2010001581A (es) * | 2007-08-16 | 2010-03-15 | Hoffmann La Roche | Hidantoinas substituidas. |
| BRPI0820696A2 (pt) | 2007-12-20 | 2019-09-24 | Hoffmann La Roche | hidantoínas substituídas como inibidores de cinase de mek |
| US8258134B2 (en) * | 2008-04-16 | 2012-09-04 | Hoffmann-La Roche Inc. | Pyridazinone glucokinase activators |
| NZ588462A (en) | 2008-04-28 | 2012-07-27 | Kyorin Seiyaku Kk | Cyclopentylacrylic acid amide derivative |
| EP2294053B1 (en) | 2008-05-16 | 2016-01-06 | Takeda California, Inc. | Glucokinase activators |
| EP2445908A1 (en) | 2009-06-22 | 2012-05-02 | Cadila Healthcare Limited | Disubstituted benzamide derivatives as glucokinase (gk) activators |
| DK2459554T3 (da) | 2009-07-31 | 2014-01-06 | Cadila Healthcare Ltd | Substituerede benzamidderivater som glucokinase (GK)-aktivatorer |
| CA2800498C (en) | 2010-03-31 | 2021-11-16 | The Scripps Research Institute | Reprogramming cells |
| ES2671881B1 (es) * | 2016-11-11 | 2019-03-25 | Consejo Superior Investigacion | Procedimiento de obtencion de polimeros con grupos isocianato |
| WO2019241089A1 (en) | 2018-06-12 | 2019-12-19 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202339A (en) * | 1987-08-28 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
| US6320050B1 (en) * | 1999-03-29 | 2001-11-20 | Hoffmann-La Roche Inc. | Heteroaromatic glucokinase activators |
| ES2248309T3 (es) * | 2000-05-03 | 2006-03-16 | F. Hoffmann-La Roche Ag | Activadores de glucoquinasa conteniendo hidantoina. |
-
2001
- 2001-04-23 ES ES01925563T patent/ES2248309T3/es not_active Expired - Lifetime
- 2001-04-23 AT AT01925563T patent/ATE304011T1/de not_active IP Right Cessation
- 2001-04-23 CA CA002407428A patent/CA2407428C/en not_active Expired - Fee Related
- 2001-04-23 WO PCT/EP2001/004555 patent/WO2001083478A2/en active IP Right Grant
- 2001-04-23 CN CNB018089135A patent/CN1209361C/zh not_active Expired - Fee Related
- 2001-04-23 DE DE60113247T patent/DE60113247T2/de not_active Expired - Lifetime
- 2001-04-23 DK DK01925563T patent/DK1280801T3/da active
- 2001-04-23 MX MXPA02010746A patent/MXPA02010746A/es active IP Right Grant
- 2001-04-23 PT PT01925563T patent/PT1280801E/pt unknown
- 2001-04-23 AU AU5227001A patent/AU5227001A/xx active Pending
- 2001-04-23 EP EP01925563A patent/EP1280801B1/en not_active Expired - Lifetime
- 2001-04-23 KR KR10-2002-7014735A patent/KR100505312B1/ko not_active IP Right Cessation
- 2001-04-23 JP JP2001580906A patent/JP3842131B2/ja not_active Expired - Fee Related
- 2001-04-23 AU AU2001252270A patent/AU2001252270B2/en not_active Ceased
- 2001-04-23 BR BR0110492-6A patent/BR0110492A/pt not_active Application Discontinuation
- 2001-04-26 US US09/843,466 patent/US6583288B2/en not_active Expired - Fee Related
- 2001-04-30 AR ARP010102036A patent/AR034253A1/es unknown
- 2001-04-30 PE PE2001000389A patent/PE20011313A1/es not_active Application Discontinuation
- 2001-05-02 UY UY26689A patent/UY26689A1/es not_active Application Discontinuation
- 2001-05-03 EC EC2001004055A patent/ECSP014055A/es unknown
-
2002
- 2002-10-17 ZA ZA200208370A patent/ZA200208370B/en unknown
-
2003
- 2003-06-04 US US10/454,041 patent/US6784298B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP014055A (es) | 2002-01-25 |
| DE60113247D1 (de) | 2005-10-13 |
| EP1280801B1 (en) | 2005-09-07 |
| AR034253A1 (es) | 2004-02-18 |
| CN1209361C (zh) | 2005-07-06 |
| CA2407428A1 (en) | 2001-11-08 |
| AU5227001A (en) | 2001-11-12 |
| UY26689A1 (es) | 2001-11-30 |
| JP3842131B2 (ja) | 2006-11-08 |
| MXPA02010746A (es) | 2003-03-10 |
| PT1280801E (pt) | 2005-11-30 |
| WO2001083478A2 (en) | 2001-11-08 |
| JP2003531905A (ja) | 2003-10-28 |
| PE20011313A1 (es) | 2001-12-28 |
| US20010056191A1 (en) | 2001-12-27 |
| KR100505312B1 (ko) | 2005-08-04 |
| BR0110492A (pt) | 2003-04-08 |
| CA2407428C (en) | 2010-02-02 |
| WO2001083478A3 (en) | 2002-05-16 |
| ATE304011T1 (de) | 2005-09-15 |
| US6784298B2 (en) | 2004-08-31 |
| KR20020093120A (ko) | 2002-12-12 |
| ES2248309T3 (es) | 2006-03-16 |
| US20030225286A1 (en) | 2003-12-04 |
| US6583288B2 (en) | 2003-06-24 |
| DE60113247T2 (de) | 2006-06-22 |
| ZA200208370B (en) | 2004-01-26 |
| AU2001252270B2 (en) | 2005-12-15 |
| EP1280801A2 (en) | 2003-02-05 |
| CN1427838A (zh) | 2003-07-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1280801T3 (da) | Hydantoinholdige glucokinaseaktivatorer | |
| DK1169312T3 (da) | Glucokinaseaktivatorer | |
| DK1242397T3 (da) | Trans-olefiniske glucokinaseaktivatorer | |
| DK1283830T3 (da) | Para-amin-substituerede phenylamidglucokinase-aktivatorer | |
| ATE297921T1 (de) | Tetrazolylphenyl-acetamide als glukokinaseaktivatoren | |
| DK1282611T3 (da) | Substituerede phenylacetatamider og anvendelse deraf som glucokinaseaktivatorer | |
| DE60126873D1 (de) | PLL-Schaltung | |
| DK1341774T3 (da) | Kondenserede heteroaromatiske glucokinase-aktivatorer | |
| DE50105915D1 (de) | Schutzhülle | |
| DE60000964T2 (de) | Glaskeramik | |
| DK1303496T3 (da) | Pyrimidinderivater | |
| DE60111792D1 (de) | Bohrwerkzeug | |
| DE60106829D1 (de) | Bohrwerkzeug | |
| NO20030276D0 (no) | Fremgangsmåte | |
| AR028336A1 (es) | 4-hidroxi-tetrahidropiridonas fenilsubstituidas | |
| NO20032291D0 (no) | Pyrimidinderivater | |
| AR028061A1 (es) | 2-enamino-cetonitrilos fenil-substituidos | |
| DE50113112D1 (de) | Schaltungsanordnung | |
| AR027931A1 (es) | Antitranspirantes | |
| AR027982A1 (es) | Aril- y heteroarilsulfonatos | |
| DE60143209D1 (de) | Zweiport-demodulationseinrichtung | |
| AT500246B8 (de) | Chokerring | |
| DE50115426D1 (de) | Schaltungsanordnung | |
| FR2817889B1 (fr) | Coffrage | |
| NO20012365L (no) | Rörpressforbindelse |