MA27467A1 - Quinolones anti-microbiens, leurs compositions et utilisations - Google Patents

Quinolones anti-microbiens, leurs compositions et utilisations

Info

Publication number
MA27467A1
MA27467A1 MA28065A MA28065A MA27467A1 MA 27467 A1 MA27467 A1 MA 27467A1 MA 28065 A MA28065 A MA 28065A MA 28065 A MA28065 A MA 28065A MA 27467 A1 MA27467 A1 MA 27467A1
Authority
MA
Morocco
Prior art keywords
microbial
quinolones
compositions
compounds
effective
Prior art date
Application number
MA28065A
Other languages
English (en)
Inventor
Benoit Ledoussal
Xiufeng Eric Hu
Ji-In Kim Almstead
Jeffrey Lyle Gray
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MA27467A1 publication Critical patent/MA27467A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Les composés de la formule suivante (I) sont efficaces en tant qu'agents anti-microbiens.
MA28065A 2002-07-31 2005-01-25 Quinolones anti-microbiens, leurs compositions et utilisations MA27467A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40001402P 2002-07-31 2002-07-31

Publications (1)

Publication Number Publication Date
MA27467A1 true MA27467A1 (fr) 2005-08-01

Family

ID=31715691

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28065A MA27467A1 (fr) 2002-07-31 2005-01-25 Quinolones anti-microbiens, leurs compositions et utilisations

Country Status (17)

Country Link
US (1) US6900224B2 (fr)
EP (1) EP1532137A2 (fr)
JP (1) JP2005536532A (fr)
KR (1) KR20050026074A (fr)
CN (1) CN1671690A (fr)
AU (1) AU2003259169A1 (fr)
BR (1) BR0313420A (fr)
CA (1) CA2493146A1 (fr)
IL (1) IL166041A0 (fr)
MA (1) MA27467A1 (fr)
MX (1) MXPA05001180A (fr)
NO (1) NO20051082L (fr)
NZ (1) NZ537203A (fr)
PL (1) PL375388A1 (fr)
RU (1) RU2005105337A (fr)
WO (1) WO2004014893A2 (fr)
ZA (1) ZA200500877B (fr)

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TR200001435T2 (tr) * 1997-09-15 2000-08-21 The Procter & Gamble Company Antimikrobiyal kuinolonlar, bunların bileşimleri ve kullanımları
ES2304989T3 (es) * 1999-12-28 2008-11-01 Teikoku Seiyaku Co., Ltd. Agente antiprurigonoso para uso externo.
BRPI0409105A (pt) * 2003-04-07 2006-04-25 Cylene Pharmaceuticals Inc análogos de quinobenzoxazina substituìdos
US7507727B2 (en) * 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
US7163948B2 (en) * 2003-04-07 2007-01-16 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydri-4ox9-1,8-naphthyridine analogs
US7354916B2 (en) * 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
BRPI0515319A (pt) * 2004-09-17 2008-07-22 Cylene Pharmaceuticals Inc análogos de quinolona
US7652134B2 (en) * 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
KR20110082635A (ko) * 2006-03-28 2011-07-19 워너 칠콧 컴퍼니 엘엘씨 퀴놀론 중간체를 제조하기 위한 커플링 방법
JP5097967B2 (ja) * 2006-03-28 2012-12-12 タイゲン バイオテクノロジー カンパニー，リミテッド リンゴ酸塩類、及び（３ｓ，５ｓ）−７−［３−アミノ−５−メチルーピペリジニル］−１−シクロプロピル−１，４−ジヒドロ−８−メトキシ−４−オキソ−３−キノリンカルボン酸の多形体類
US7528264B2 (en) 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
CN101595109B (zh) * 2006-11-20 2012-09-05 百时美施贵宝公司 作为二肽基肽酶ⅳ抑制剂的7，8-二氢-1，6-二氮杂萘-5（6h）-酮和相关二环化合物及方法
US8658183B2 (en) * 2007-08-09 2014-02-25 Taigen Biotechnology Company, Ltd. Antimicrobial parenteral formulation
WO2009046383A1 (fr) 2007-10-05 2009-04-09 Cylene Pharmaceuticals, Inc. Analogues de quinolone et procédés associés
KR20150006080A (ko) * 2008-07-01 2015-01-15 타이젠 바이오테크놀러지 컴퍼니 리미티드 항생제 내성 세균 감염의 치료
CN101618039B (zh) * 2008-07-02 2012-04-11 太景生物科技股份有限公司 肺炎的治疗药物
FR2936798B1 (fr) * 2008-10-03 2012-09-28 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.
FR2937034B1 (fr) * 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
FR2936951B1 (fr) * 2008-10-10 2010-12-03 Novexel Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments
CA2743700C (fr) * 2008-12-15 2016-07-12 Taigen Biotechnology Co., Ltd. Synthese stereoselective de derives de piperidine
CN102093260B (zh) * 2009-12-14 2014-03-05 太景生物科技股份有限公司 哌啶衍生物的立体有择合成
CN108601789A (zh) 2015-11-20 2018-09-28 生华生物科技股份有限公司 用于治疗癌症的四环喹诺酮类似物组合疗法
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
EP3394061B1 (fr) 2015-12-23 2020-03-11 Merck Sharp & Dohme Corp. Modulateurs allostériques 6,7-dihydro-5h-pyrrolo[3,4-b]pyridine-5-one du récepteur de l'acétylcholine muscarinique m4
WO2017107089A1 (fr) 2015-12-23 2017-06-29 Merck Sharp & Dohme Corp. Modulateurs allostériques 3-(1h-pyrazol-4-yl)pyridine du récepteur muscarinique m4 de l'acétylcholine
WO2018112843A1 (fr) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. Modulateurs allostériques d'éther hétéroarylpipéridine du récepteur muscarinique de l'acétylcholine m4
WO2018112842A1 (fr) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. Modulateurs allostériques d'éther hétéroarylpipéridine 6,6-fusionné du récepteur muscarinique de l'acétylcholine m4
WO2018112840A1 (fr) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. Modulateurs allostériques d'éther d'hétéroarylpipéridine 6, 5-fusionnés du récepteur muscarinique d'acétylcholine m4
WO2019000237A1 (fr) 2017-06-27 2019-01-03 Merck Sharp & Dohme Corp. Modulateurs allostériques de 3-(1h-pyrazol-4-yl)pyridine du récepteur muscarinique m4 de l'acétylcholine
WO2019000236A1 (fr) 2017-06-27 2019-01-03 Merck Sharp & Dohme Corp. Modulateurs allostériques de 3-(1h-pyrazol-4-yl)pyridine du récepteur muscarinique m4 de l'acétylcholine
WO2019000238A1 (fr) 2017-06-27 2019-01-03 Merck Sharp & Dohme Corp. Modulateurs allostériques de 5-(pyridin-3-yl)oxazole du récepteur muscarinique m4 de l'acétylcholine
WO2019168688A2 (fr) 2018-02-15 2019-09-06 Senhwa Biosciences, Inc. Analogues de quinolone, sels correspondants, compositions et procédé d'utilisation
CR20200502A (es) 2018-04-25 2020-12-22 Bayer Animal Health Gmbh Proceso para la hidrólisis de ésteres carboxílicos de quinolona

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE117685T1 (de) 1988-05-19 1995-02-15 Chugai Pharmaceutical Co Ltd Chinoloncarbonsäure-derivate.
DE69430581D1 (de) * 1993-10-14 2002-06-13 Abbott Lab Verbindungen des chinolizinon-typs
IL122296A0 (en) * 1995-06-06 1998-04-05 Abbott Lab Quinolizinone type compounds
KR100241673B1 (ko) * 1997-08-09 2000-03-02 김충섭 퀴놀리진 카르복실산 유도체
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
TR200001435T2 (tr) 1997-09-15 2000-08-21 The Procter & Gamble Company Antimikrobiyal kuinolonlar, bunların bileşimleri ve kullanımları
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
EA005585B1 (ru) * 2000-01-24 2005-04-28 Уорнер-Ламберт Компани 3-аминохиназолин-2,4-дионовые антибактериальные агенты
JP2004515548A (ja) 2000-12-14 2004-05-27 ザ プロクター アンド ギャンブル カンパニー 抗微生物キノロン

Also Published As

Publication number Publication date
NZ537203A (en) 2007-02-23
JP2005536532A (ja) 2005-12-02
WO2004014893A2 (fr) 2004-02-19
MXPA05001180A (es) 2005-05-16
EP1532137A2 (fr) 2005-05-25
RU2005105337A (ru) 2006-01-20
CA2493146A1 (fr) 2004-02-19
PL375388A1 (en) 2005-11-28
NO20051082L (no) 2005-04-29
WO2004014893A3 (fr) 2004-04-08
IL166041A0 (en) 2006-01-15
CN1671690A (zh) 2005-09-21
KR20050026074A (ko) 2005-03-14
US6900224B2 (en) 2005-05-31
ZA200500877B (en) 2006-02-20
AU2003259169A1 (en) 2004-02-25
US20040038975A1 (en) 2004-02-26
BR0313420A (pt) 2005-06-28

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